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A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCG-refractory and BCG-intolerant patients

Drug design, development and therapy, 2010-11, Vol.4 (default), p.313-320

2010

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A phase I clinical study of VB4-845: Weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck

Drug design, development and therapy, 2008, Vol.2, p.105

Spearman, Maureen

2008

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A Phase II Study of Oportuzumab Monatox: An Immunotoxin Therapy for Patients with Noninvasive Urothelial Carcinoma In Situ Previously Treated with Bacillus Calmette-Guérin

The Journal of urology, 2012-11, Vol.188 (5), p.1712-1718

2012

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Trastuzumab-deBouganin Conjugate Overcomes Multiple Mechanisms of T-DM1 Drug Resistance

Journal of immunotherapy (1997), 2016-04, Vol.39 (3), p.117-126

2016

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Abstract 2961: deBouganin conjugated to trastuzumab overcomes multiple mechanisms of T-DM1 drug resistance

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2961-2961

2016

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Engineering and biological characterization of VB6-845, an anti-EpCAM immunotoxin containing a T-cell epitope-depleted variant of the plant toxin bouganin

Journal of immunotherapy, 2009-07, Vol.32 (6), p.574-584

2009

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HA receptors: Regulators of signalling to the cytoskeleton

Journal of cellular biochemistry, 1996-06, Vol.61 (4), p.569-577

1996

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Abstract 2963: VB7-756: a Her2-specific diabody armed with deBouganin, a plant toxin with a distinct MOA

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2963-2963

2016

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The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains

Gene, 1996, Vol.174 (2), p.299-306

1996

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Preclinical evaluation of VB6-845: an anti-EpCAM immunotoxin with reduced immunogenic potential

Cancer biotherapy & radiopharmaceuticals, 2012-11, Vol.27 (9), p.582-592

2012

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Characterization of the murine gene encoding the hyaluronan receptor RHAMM

Gene, 1995-10, Vol.163 (2), p.233-238

1995

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Development of a GMP Phase III purification process for VB4-845, an immunotoxin expressed in E. coli using high cell density fermentation

Protein expression and purification, 2011-07, Vol.78 (1), p.27-37

2011

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A targeted proteomic approach for the identification of tumor-associated membrane antigens using the ProteomeLab ™ PF-2D in tandem with mass spectrometry

Biochemical and biophysical research communications, 2006-09, Vol.348 (3), p.1055-1062

2006

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Preclinical assessment of an anti-EpCAM immunotoxin: locoregional delivery provides a safer alternative to systemic administration

Cancer biotherapy & radiopharmaceuticals, 2009-08, Vol.24 (4), p.477-487

2009

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Primary structure of a C-hordein gene from barley

Carlsberg research communications, 1988, Vol.53 (4), p.247-258

ENTWISTLE, J

1988

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1575: A Phase I/II Study of Vicinium™ Given by Intravesical Administration in Patients with Superficial Transitional Cell Carcinoma of the Bladder: Phase I Final Results

The Journal of urology, 2007-04, Vol.177 (4), p.521-521

2007

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A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCGrefractory and BCG-intolerant patients

Drug design, development and therapy, 2010-11, Vol.4, p.313-320

2010

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A phase I clinical study of VB4-845: weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck

Drug design, development and therapy, 2009-02, Vol.2, p.105-114

2009

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Amber codon suppression: the in vivo and in vitro analysis of two C-hordein genes from barley

Plant molecular biology, 1991-12, Vol.17 (6), p.1217-1231

1991

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Transforming Growth Factor-Î²1 Stimulates Multiple Protein Interactions at a Unique cis-Element in the 3â²-Untranslated Region of the Hyaluronan Receptor RHAMM mRNA

The Journal of biological chemistry, 1996-06, Vol.271 (25), p.15279

1996

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Transforming Growth Factor-β1 Stimulates Multiple Protein Interactions at a Unique -Element in the 3′-Untranslated Region of the Hyaluronan Receptor RHAMM mRNA

The Journal of biological chemistry, 1996-06, Vol.271 (25), p.15279-15284

1996

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Preclinical Safety Evaluation of Immunotoxins

Preclinical Safety Evaluation of Biopharmaceuticals, 2008, p.649-667

2008

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A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCG-refractory and BCG-intolerant patients

A phase I clinical study of VB4-845: Weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck

A Phase II Study of Oportuzumab Monatox: An Immunotoxin Therapy for Patients with Noninvasive Urothelial Carcinoma In Situ Previously Treated with Bacillus Calmette-Guérin

Trastuzumab-deBouganin Conjugate Overcomes Multiple Mechanisms of T-DM1 Drug Resistance

Abstract 2961: deBouganin conjugated to trastuzumab overcomes multiple mechanisms of T-DM1 drug resistance

Engineering and biological characterization of VB6-845, an anti-EpCAM immunotoxin containing a T-cell epitope-depleted variant of the plant toxin bouganin

HA receptors: Regulators of signalling to the cytoskeleton

Abstract 2963: VB7-756: a Her2-specific diabody armed with deBouganin, a plant toxin with a distinct MOA

The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains

Preclinical evaluation of VB6-845: an anti-EpCAM immunotoxin with reduced immunogenic potential

Characterization of the murine gene encoding the hyaluronan receptor RHAMM

Development of a GMP Phase III purification process for VB4-845, an immunotoxin expressed in E. coli using high cell density fermentation

A targeted proteomic approach for the identification of tumor-associated membrane antigens using the ProteomeLab ™ PF-2D in tandem with mass spectrometry

Preclinical assessment of an anti-EpCAM immunotoxin: locoregional delivery provides a safer alternative to systemic administration

Primary structure of a C-hordein gene from barley

1575: A Phase I/II Study of Vicinium™ Given by Intravesical Administration in Patients with Superficial Transitional Cell Carcinoma of the Bladder: Phase I Final Results

A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCGrefractory and BCG-intolerant patients

A phase I clinical study of VB4-845: weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck

Amber codon suppression: the in vivo and in vitro analysis of two C-hordein genes from barley

Transforming Growth Factor-Î²1 Stimulates Multiple Protein Interactions at a Unique cis-Element in the 3â²-Untranslated Region of the Hyaluronan Receptor RHAMM mRNA

Transforming Growth Factor-β1 Stimulates Multiple Protein Interactions at a Unique -Element in the 3′-Untranslated Region of the Hyaluronan Receptor RHAMM mRNA

Preclinical Safety Evaluation of Immunotoxins

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