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Enantioselective Synthesis of the Pyrroloquinoline Core of the Martinellines

Organic letters, 2000-05, Vol.2 (10), p.1395-1397

2000

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Synthesis of 3-Methoxycarbonylmethyl Derivatives of Dihydroquinolone and Dihydrochromenone

Journal of organic chemistry, 2001-03, Vol.66 (6), p.2175-2177

2001

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Thienopyrimidine-based P2Y12 platelet aggregation inhibitors

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5919-5923

2009

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Asymmetric Synthesis of Cis-Fused Bicyclic Pyrrolidines and Pyrrolidinones via Chiral Polycyclic Lactams

Journal of organic chemistry, 1996-08, Vol.61 (17), p.5813-5817

1996

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Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: total synthesis of (+)-macbecin

Journal of organic chemistry, 1993, Vol.58 (2), p.471-485

1993

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Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4657-4663

2009

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Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6148-6156

2009

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Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (4), p.1388-1394

2010

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Isochroman-6-carboxamides as Highly Selective 5-HT1D Agonists: Potential New Treatment for Migraine without Cardiovascular Side Effects

Journal of medicinal chemistry, 1998-06, Vol.41 (13), p.2180-2183

1998

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2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: New templates for 5-HT2C agonists

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (14), p.2369-2372

2003

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Structure-Activity Relationships in the 8-Amino-6,7,8,9-tetrahydro-3H-benz[e]indole Ring System. Part 2: Effect of 8-Amino Nitrogen Substitution on Serotonin Receptor Binding and Pharmacology

Journal of medicinal chemistry, 1995-06, Vol.38 (12), p.2217-2230

1995

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Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y 12 Antagonists for Inhibition of Platelet Aggregation

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.2010-2037

2010

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5-HT1D Receptor Agonist Properties of Novel 2-[5-[[(Trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and Their Use as Synthetic Intermediates

Journal of medicinal chemistry, 1996-11, Vol.39 (24), p.4717-4726

1996

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Asymmetric synthesis of macbecin I

Journal of organic chemistry, 1992-02, Vol.57 (4), p.1067-1069

1992

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The synthesis of (+)-and(−)-flesinoxan: Application of enzymatic resolution methodology

Tetrahedron letters, 1992-10, Vol.33 (42), p.6287-6290

1992

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Enzymatic resolution of 2-Hydroxymethyl-1,4-benzodioxanes

Tetrahedron letters, 1992-10, Vol.33 (42), p.6283-6286

1992

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Overview: The Search for 5-HT1A Antagonists

Expert opinion on therapeutic patents, 1993-09, Vol.3 (9), p.1325-1333

Ennis, Michael D

1993

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Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y12 Antagonists for Inhibition of Platelet Aggregation

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.2010-2037

2010

Volltextzugriff (PDF)

Thienopyrimidine-based P2Y sub(12) platelet aggregation inhibitors

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5919-5923

2009

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Differential pharmacology between the guinea‐pig and the gorilla 5‐HT 1D receptor as probed with isochromans (5‐HT 1D ‐selective ligands)

British journal of pharmacology, 2009-01, Vol.127 (2), p.468-472

2009

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Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y 12 antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (4), p.1388-1394

2010

Volltextzugriff (PDF)

Thienopyrimidine-based P2Y 12 platelet aggregation inhibitors

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (20), p.5919-5923

2009

Volltextzugriff (PDF)

Piperazinyl-glutamate-pyrimidines as potent P2Y sub(12) antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6148-6156

2009

Volltextzugriff (PDF)

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y sub(12) antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4657-4663

2009

Volltextzugriff (PDF)

Structure-Activity Relationships in the 8-Amino-6,7,8,9-tetrahydro-3H-benz[e]indole Ring System. Part 1: Effects of Substituents in the Aromatic System on Serotonin and Dopamine Receptor Subtypes

Journal of medicinal chemistry, 1995-06, Vol.38 (12), p.2202-2216

1995

Volltextzugriff (PDF)

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Enantioselective Synthesis of the Pyrroloquinoline Core of the Martinellines

Synthesis of 3-Methoxycarbonylmethyl Derivatives of Dihydroquinolone and Dihydrochromenone

Thienopyrimidine-based P2Y12 platelet aggregation inhibitors

Asymmetric Synthesis of Cis-Fused Bicyclic Pyrrolidines and Pyrrolidinones via Chiral Polycyclic Lactams

Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: total synthesis of (+)-macbecin

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation

Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Isochroman-6-carboxamides as Highly Selective 5-HT1D Agonists: Potential New Treatment for Migraine without Cardiovascular Side Effects

2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: New templates for 5-HT2C agonists

Structure-Activity Relationships in the 8-Amino-6,7,8,9-tetrahydro-3H-benz[e]indole Ring System. Part 2: Effect of 8-Amino Nitrogen Substitution on Serotonin Receptor Binding and Pharmacology

Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y 12 Antagonists for Inhibition of Platelet Aggregation

5-HT1D Receptor Agonist Properties of Novel 2-[5-[[(Trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and Their Use as Synthetic Intermediates

Asymmetric synthesis of macbecin I

The synthesis of (+)-and(−)-flesinoxan: Application of enzymatic resolution methodology

Enzymatic resolution of 2-Hydroxymethyl-1,4-benzodioxanes

Overview: The Search for 5-HT1A Antagonists

Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y12 Antagonists for Inhibition of Platelet Aggregation

Thienopyrimidine-based P2Y sub(12) platelet aggregation inhibitors

Differential pharmacology between the guinea‐pig and the gorilla 5‐HT 1D receptor as probed with isochromans (5‐HT 1D ‐selective ligands)

Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y 12 antagonists for inhibition of platelet aggregation

Thienopyrimidine-based P2Y 12 platelet aggregation inhibitors

Piperazinyl-glutamate-pyrimidines as potent P2Y sub(12) antagonists for inhibition of platelet aggregation

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y sub(12) antagonists for inhibition of platelet aggregation

Structure-Activity Relationships in the 8-Amino-6,7,8,9-tetrahydro-3H-benz[e]indole Ring System. Part 1: Effects of Substituents in the Aromatic System on Serotonin and Dopamine Receptor Subtypes

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