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AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease

Human molecular genetics, 2013-05, Vol.22 (10), p.2083-2096

2013

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Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation

Cellular and molecular life sciences : CMLS, 2008-01, Vol.65 (1), p.80-88

2008

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Synphilin Isoforms and the Search for a Cellular Model of Lewy Body Formation in Parkinson's Disease

Cell cycle (Georgetown, Tex.), 2006-09, Vol.5 (18), p.2082-2086

2006

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Huntingtin-Associated Protein 1 (HAP1) Binds to a Trio-Like Polypeptide, with a rac1 Guanine Nucleotide Exchange Factor Domain

Human molecular genetics, 1997-09, Vol.6 (9), p.1519-1525

1997

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Mutation analysis of the seven in absentia homolog 1 (SIAH1) gene in Parkinson's disease

Journal of Neural Transmission, 2006-12, Vol.113 (12), p.1903-1908

2006

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Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation

The Journal of neuroscience, 2005-02, Vol.25 (8), p.2002-2009

2005

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Ubiquitylation of Synphilin-1 and α-Synuclein by SIAH and Its Presence in Cellular Inclusions and Lewy Bodies Imply a Role in Parkinson's Disease

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (15), p.5500-5505

2004

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Pharmacological differentiation between intracellular calcium pump isoforms

Molecular pharmacology, 1996-11, Vol.50 (5), p.1243-1252

1996

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Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

Human molecular genetics, 2001-04, Vol.10 (9), p.919-926

2001

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Genetic Analysis of Synphilin-1 in Familial Parkinson's Disease

Neurobiology of disease, 2001-04, Vol.8 (2), p.317-323

2001

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Synphilin-1 is present in Lewy bodies in Parkinson's disease

Annals of neurology, 2000-04, Vol.47 (4), p.521-523

2000

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Human serine racemase: moleular cloning, genomic organization and functional analysis

Gene, 2000-10, Vol.256 (1), p.183-188

2000

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Glycogen Synthase Kinase 3 beta Modulates Synphilin-1 Ubiquitylation and Cellular Inclusion Formation by SIAH: Implications for Proteasomal Function and Lewy Body Formation

The Journal of biological chemistry, 2005-12, Vol.280 (52), p.42877-42886

2005

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Synphilin-1A: An Aggregation-Prone Isoform of Synphilin-1 That Causes Neuronal Death and Is Present in Aggregates from α-Synucleinopathy Patients

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (15), p.5917-5922

2006

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Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions

Nature genetics, 1999-05, Vol.22 (1), p.110-114

1999

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Pathogenesis of neurodegenerative diseases associated with expanded glutamine repeats: new answers, new questions

Progress in brain research, 1998, Vol.117, p.397

1998

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proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease

The FASEB journal, 2007-06, Vol.21 (8), p.1759-1767

2007

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Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

Human molecular genetics, 2003-06, Vol.12 (11), p.1223-1231

2003

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Synphilin-1 Is Developmentally Localized to Synaptic Terminals, and Its Association with Synaptic Vesicles Is Modulated by α-Synuclein

The Journal of biological chemistry, 2002-06, Vol.277 (26), p.23927-23933

2002

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Inhibition of creatine kinase by S-nitrosoglutathione

FEBS letters, 1996-09, Vol.392 (3), p.274-276

1996

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Human huntingtin-associated protein (HAP-1) gene: genomic organisation and an intragenic polymorphism

Gene, 2000-08, Vol.254 (1), p.181-187

2000

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Immunocytochemical localization of synphilin-1, an α-synuclein-associated protein, in neurodegenerative disorders

Acta neuropathologica, 2002-03, Vol.103 (3), p.209-214

2002

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Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap1

Mammalian genome, 1998-07, Vol.9 (7), p.565-570

1998

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A New Strategy to Decrease N-Methyl-D-Aspartate (NMDA) Receptor Coactivation: Inhibition of D-Serine Synthesis by Converting Serine Racemase into an Eliminase

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.5294-5299

2001

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Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

Neurobiology of disease, 2005-11, Vol.20 (2), p.401-411

2005

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AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease

Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation

Synphilin Isoforms and the Search for a Cellular Model of Lewy Body Formation in Parkinson's Disease

Huntingtin-Associated Protein 1 (HAP1) Binds to a Trio-Like Polypeptide, with a rac1 Guanine Nucleotide Exchange Factor Domain

Mutation analysis of the seven in absentia homolog 1 (SIAH1) gene in Parkinson's disease

Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation

Ubiquitylation of Synphilin-1 and α-Synuclein by SIAH and Its Presence in Cellular Inclusions and Lewy Bodies Imply a Role in Parkinson's Disease

Pharmacological differentiation between intracellular calcium pump isoforms

Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

Genetic Analysis of Synphilin-1 in Familial Parkinson's Disease

Synphilin-1 is present in Lewy bodies in Parkinson's disease

Human serine racemase: moleular cloning, genomic organization and functional analysis

Glycogen Synthase Kinase 3 beta Modulates Synphilin-1 Ubiquitylation and Cellular Inclusion Formation by SIAH: Implications for Proteasomal Function and Lewy Body Formation

Synphilin-1A: An Aggregation-Prone Isoform of Synphilin-1 That Causes Neuronal Death and Is Present in Aggregates from α-Synucleinopathy Patients

Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions

Pathogenesis of neurodegenerative diseases associated with expanded glutamine repeats: new answers, new questions

proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease

Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

Synphilin-1 Is Developmentally Localized to Synaptic Terminals, and Its Association with Synaptic Vesicles Is Modulated by α-Synuclein

Inhibition of creatine kinase by S-nitrosoglutathione

Human huntingtin-associated protein (HAP-1) gene: genomic organisation and an intragenic polymorphism

Immunocytochemical localization of synphilin-1, an α-synuclein-associated protein, in neurodegenerative disorders

Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap1

A New Strategy to Decrease N-Methyl-D-Aspartate (NMDA) Receptor Coactivation: Inhibition of D-Serine Synthesis by Converting Serine Racemase into an Eliminase

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

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