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Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia

PloS one, 2011-06, Vol.6 (6), p.e20656

2011

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Host Metabolism Regulates Intracellular Growth of Trypanosoma cruzi

Cell host & microbe, 2013-01, Vol.13 (1), p.108-117

2013

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A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit

PLoS neglected tropical diseases, 2011-07, Vol.5 (7), p.e1253

2011

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The Trypanosoma cruzi protease cruzain mediates immune evasion

PLoS pathogens, 2011-09, Vol.7 (9), p.e1002139-e1002139

2011

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A Cysteine Protease Inhibitor Cures Chagas' Disease in an Immunodeficient-Mouse Model of Infection

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3932-3939

2007

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Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3326-3334

2010

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Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51

PLoS neglected tropical diseases, 2012-07, Vol.6 (7), p.e1736-e1736

2012

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A Nonazole CYP51 Inhibitor Cures Chagas’ Disease in a Mouse Model of Acute Infection

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2480-2488

2010

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A Contiguous Compartment Functions as Endoplasmic Reticulum and Endosome/Lysosome in Giardia lamblia

Eukaryotic Cell, 2009-11, Vol.8 (11), p.1665-1676

2009

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Cathepsin Cs Are Key for the Intracellular Survival of the Protozoan Parasite, Toxoplasma gondii

The Journal of biological chemistry, 2007-02, Vol.282 (7), p.4994-5003

2007

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Mining a cathepsin inhibitor library for new antiparasitic drug leads

PLoS neglected tropical diseases, 2011-05, Vol.5 (5), p.e1023-e1023

2011

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Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1763-1773

2010

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Liver Cytochrome P450 3A Ubiquitination in Vivo by gp78/Autocrine Motility Factor Receptor and C Terminus of Hsp70-interacting Protein (CHIP) E3 Ubiquitin Ligases: PHYSIOLOGICAL AND PHARMACOLOGICAL RELEVANCE

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35866-35877

2010

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Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol

The Journal of biological chemistry, 2011-02, Vol.286 (5), p.3815-3828

2011

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

The Journal of experimental medicine, 1998-08, Vol.188 (4), p.725-734

1998

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Diversity-Oriented Synthesis Yields a New Drug Lead for Treatment of Chagas Disease

ACS medicinal chemistry letters, 2014-02, Vol.5 (2), p.149-153

2014

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Cysteine protease inhibitors as chemotherapy for parasitic infections

Bioorganic & medicinal chemistry, 1999-04, Vol.7 (4), p.639-644

1999

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Liver Cytochrome P450 3A Endoplasmic Reticulum-associated Degradation

The Journal of biological chemistry, 2011-02, Vol.286 (5), p.3815-3828

2011

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Development of α-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease

Bioorganic & medicinal chemistry, 2005-03, Vol.13 (6), p.2141-2156

2005

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Cysteine Protease Inhibitors as Chemotherapy: Lessons from a Parasite Target

Proceedings of the National Academy of Sciences - PNAS, 1999-09, Vol.96 (20), p.11015-11022

1999

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Cell Biology of Pathogenic Protozoa and Their Interaction with Host Cells

BioMed research international, 2014-01, Vol.2014 (2014), p.1-2

2014

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Liver Cytochrome P450 3A Ubiquitination in Vivo by gp78/Autocrine Motility Factor Receptor and C Terminus of Hsp70-interacting Protein (CHIP) E3 Ubiquitin Ligases

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35866-35877

2010

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Biolistic transformation of Schistosoma mansoni: Studies with modified reporter-gene constructs containing regulatory regions of protease genes

Molecular and biochemical parasitology, 2010-03, Vol.170 (1), p.37-40

2010

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Drugs targeting parasite lysosomes

Current pharmaceutical design, 2008-03, Vol.14 (9), p.889-900

2008

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Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2759-2762

2001

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Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia

Host Metabolism Regulates Intracellular Growth of Trypanosoma cruzi

A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit

The Trypanosoma cruzi protease cruzain mediates immune evasion

A Cysteine Protease Inhibitor Cures Chagas' Disease in an Immunodeficient-Mouse Model of Infection

Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51

A Nonazole CYP51 Inhibitor Cures Chagas’ Disease in a Mouse Model of Acute Infection

A Contiguous Compartment Functions as Endoplasmic Reticulum and Endosome/Lysosome in Giardia lamblia

Cathepsin Cs Are Key for the Intracellular Survival of the Protozoan Parasite, Toxoplasma gondii

Mining a cathepsin inhibitor library for new antiparasitic drug leads

Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy

Liver Cytochrome P450 3A Ubiquitination in Vivo by gp78/Autocrine Motility Factor Receptor and C Terminus of Hsp70-interacting Protein (CHIP) E3 Ubiquitin Ligases: PHYSIOLOGICAL AND PHARMACOLOGICAL RELEVANCE

Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

Diversity-Oriented Synthesis Yields a New Drug Lead for Treatment of Chagas Disease

Cysteine protease inhibitors as chemotherapy for parasitic infections

Liver Cytochrome P450 3A Endoplasmic Reticulum-associated Degradation

Development of α-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease

Cysteine Protease Inhibitors as Chemotherapy: Lessons from a Parasite Target

Cell Biology of Pathogenic Protozoa and Their Interaction with Host Cells

Liver Cytochrome P450 3A Ubiquitination in Vivo by gp78/Autocrine Motility Factor Receptor and C Terminus of Hsp70-interacting Protein (CHIP) E3 Ubiquitin Ligases

Biolistic transformation of Schistosoma mansoni: Studies with modified reporter-gene constructs containing regulatory regions of protease genes

Drugs targeting parasite lysosomes

Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

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