UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Structural insights into the functional diversity of the CDK–cyclin family

Open biology, 2018-09, Vol.8 (9)

2018

Volltextzugriff (PDF)

The Structural Basis for Control of Eukaryotic Protein Kinases

Annual review of biochemistry, 2012-01, Vol.81 (1), p.587-613

2012

Volltextzugriff (PDF)

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK

Nature communications, 2015-04, Vol.6 (1), p.6769-6769, Article 6769

2015

Volltextzugriff (PDF)

Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation

Cell reports (Cambridge), 2023-03, Vol.42 (3), p.112139-112139, Article 112139

2023

Volltextzugriff (PDF)

Chatterboxes: the structural and functional diversity of cyclins

Seminars in cell & developmental biology, 2020-11, Vol.107, p.4-20

2020

Volltextzugriff (PDF)

FragLitesMinimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3741-3752

2019

Volltextzugriff (PDF)

Cryo-EM structure of the CDK2-cyclin A-CDC25A complex

Nature communications, 2024-08, Vol.15 (1), p.6807-14, Article 6807

2024

Volltextzugriff (PDF)

Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition

Cell chemical biology, 2019-01, Vol.26 (1), p.121-130.e5

2019

Volltextzugriff (PDF)

Structure-based discovery of cyclin-dependent protein kinase inhibitors

Essays in biochemistry, 2017-11, Vol.61 (5), p.439-452

2017

Volltextzugriff (PDF)

Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1

Scientific reports, 2023-07, Vol.13 (1), p.10718-10718, Article 10718

2023

Volltextzugriff (PDF)

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK‑2 Selectivity of 6‑Substituted 2‑Arylaminopurines

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.1746-1767

2017

Volltextzugriff (PDF)

Protein Kinase Inhibitors: Insights into Drug Design from Structure

Science (American Association for the Advancement of Science), 2004-03, Vol.303 (5665), p.1800-1805

2004

Volltextzugriff (PDF)

Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1386-1398

2017

Volltextzugriff (PDF)

Substituted 4‑(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X‑ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.640-659

2013

Volltextzugriff (PDF)

Emerging approaches to CDK inhibitor development, a structural perspective

RSC chemical biology, 2023-02, Vol.4 (2), p.146-164

2023

Volltextzugriff (PDF)

Recent developments in cyclin-dependent kinase biochemical and structural studies

Biochimica et biophysica acta, 2010-03, Vol.1804 (3), p.511-519

2010

Volltextzugriff (PDF)

Structural characterization of the cyclin-dependent protein kinase family

Biochemical Society transactions, 2013-08, Vol.41 (4), p.1008-1016

2013

Volltextzugriff (PDF)

Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLitesHalogenated Probes of Druglike and Peptide-like Molecular Interactions

Journal of medicinal chemistry, 2022-11, Vol.65 (22), p.15416-15432

2022

Volltextzugriff (PDF)

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4071-4088

2021

Volltextzugriff (PDF)

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.737-751

2008

Volltextzugriff (PDF)

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Journal of medicinal chemistry, 2011-03, Vol.54 (5), p.1233-1243

2011

Volltextzugriff (PDF)

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation

Journal of molecular biology, 2021-03, Vol.433 (5), p.166795-166795, Article 166795

2021

Volltextzugriff (PDF)

A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway

Cell, 2014-05, Vol.157 (5), p.1130-1145

2014

Volltextzugriff (PDF)

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

Cancer cell, 2013-05, Vol.23 (5), p.618-633

2013

Volltextzugriff (PDF)

The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b

Structure (London), 2012-10, Vol.20 (10), p.1788-1795

2012

Volltextzugriff (PDF)

1 – 25 von 136

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(123)
Mit Volltextzugriff
(125)

Publikationsform

Sprache

Englisch
(136)
Japanisch
(19)

Erscheinungsjahr

n.n

Thema

Science & Technology
(98)
Life Sciences & Biomedicine
(79)
Humans
(62)
Models, Molecular
(46)
Biochemistry & Molecular Biology
(39)
Crystallography, X-Ray
(38)
Structure-Activity Relationship
(30)
Animals
(29)
Pharmacology & Pharmacy
(27)
Protein Binding
(23)
Binding Sites
(22)
Chemistry, Medicinal
(22)
Cyclin-Dependent Kinase 2
(21)
Physical Sciences
(20)
Cell Biology
(19)
Chemistry
(19)
Drug Design
(19)
Antineoplastic Agents - Pharmacology
(18)
Cell Cycle
(18)
Cyclin-Dependent Kinases - Metabolism
(18)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Structural insights into the functional diversity of the CDK–cyclin family

The Structural Basis for Control of Eukaryotic Protein Kinases

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK

Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation

Chatterboxes: the structural and functional diversity of cyclins

FragLitesMinimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation

Cryo-EM structure of the CDK2-cyclin A-CDC25A complex

Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition

Structure-based discovery of cyclin-dependent protein kinase inhibitors

Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK‑2 Selectivity of 6‑Substituted 2‑Arylaminopurines

Protein Kinase Inhibitors: Insights into Drug Design from Structure

Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System

Substituted 4‑(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X‑ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities

Emerging approaches to CDK inhibitor development, a structural perspective

Recent developments in cyclin-dependent kinase biochemical and structural studies

Structural characterization of the cyclin-dependent protein kinase family

Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLitesHalogenated Probes of Druglike and Peptide-like Molecular Interactions

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation

A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b

Suchergebnisse filtern