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Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G‑Quadruplex and Downregulate MYC

Journal of the American Chemical Society, 2019-07, Vol.141 (28), p.11059-11070

2019

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Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors

Molecular cancer therapeutics, 2018-08, Vol.17 (8), p.1694-1704

2018

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Synthesis of Benzo[1,6]naphthyridinones Using the Catellani Reaction

Organic letters, 2018-09, Vol.20 (17), p.5228-5232

2018

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Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400)

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4890-4899

2016

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Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl–DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl–DNA Phosphodiesterase 2 (Tdp2)

Journal of medicinal chemistry, 2017-04, Vol.60 (8), p.3275-3288

2017

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Design and Synthesis of Chlorinated and Fluorinated 7‑Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5364-5376

2017

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Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors

PloS one, 2012-11, Vol.7 (11), p.e49284

2012

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Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[c]pyrrolo[2,3‑h][1,6]naphthyridin-5-one (BPN) Series

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10440-10462

2018

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Analyzing the Influence of eWOM on Customer Perception of Value and Brand Love in Hospitality Enterprise

Sustainability, 2023-04, Vol.15 (9), p.7286

2023

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Synthesis of indolo[4,3-bc]phenanthridine-6,11(2H,12H)-diones using the schiff base-homophthalic anhydride cyclization reaction

Synthetic communications, 2016-01, Vol.46 (23), p.1902-1908

2016

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Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitors

Organic & biomolecular chemistry, 2017-12, Vol.16 (1), p.108-118

2017

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Isolation and characterization of Salmonella Enteritidis and Salmonella Typhimurium from chicken meat in Egypt

Journal of infection in developing countries, 2017-04, Vol.11 (4), p.314-319

2017

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Service Value and Repurchase Intention in the Egyptian Fast-Food Restaurants: Toward a New Measurement Model

International journal of environmental research and public health, 2022-11, Vol.19 (23), p.15779

2022

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Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology

Journal of nanomaterials, 2022, Vol.2022 (1)

2022

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Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.14466-14477

2024

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Discovery of 5‑Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors

ACS medicinal chemistry letters, 2023-12, Vol.14 (12), p.1673-1681

2023

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Design, synthesis and molecular modeling study of certain 4-Methylbenzenesulfonamides with CDK2 inhibitory activity as anticancer and radio-sensitizing agents

Bioorganic chemistry, 2018-10, Vol.80, p.276-287

2018

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Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors

European journal of medicinal chemistry, 2013-03, Vol.61, p.122-131

2013

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Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitorsElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob02386c

2017-12

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Abstract 2662: Indenoisoquinoline topoisomerase I inhibitors target the DNA G-quadruplex formed in the c-Myc promoter and cause MYC downregulation

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2662-2662

2018

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UNDERSTANDING THE INFLUENCE OF FOOD VALUE ON FAST-FOOD CUSTOMER BEHAVIOR: A STUDY ON THE MEDIATING ROLE OF BLOGGER REVIEWS AND MODERATING EFFECT OF CONTENT CREDIBILITY

GeoJournal of tourism and geosites, 2024-01, Vol.52 (1), p.9-19

2024

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CPAP for acute cardiogenic pulmonary oedema from out-of-hospital to cardiac intensive care unit: a randomised multicentre study

Intensive care medicine, 2011-09, Vol.37 (9), p.1501-1509

2011

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Design, Synthesis and Biological Evaluation of Some Topoisomerase Type 1 Poisons, Cox-2 Selective Agents, and Protein Kinase Inhibitors

Elsayed, Mohamed S. A

2018

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Structure-based predictive model for some benzimidazole inhibitors of hepatitis C virus NS5B polymerase

Medicinal chemistry research, 2013-04, Vol.22 (4), p.1866-1883

2013

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Supramolecular Self‐Assembled Nanospheres for Enzyme Encapsulation Based on Cyclodextrin

Journal of chemistry, 2024-01, Vol.2024 (1)

2024

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Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G‑Quadruplex and Downregulate MYC

Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors

Synthesis of Benzo[1,6]naphthyridinones Using the Catellani Reaction

Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400)

Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl–DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl–DNA Phosphodiesterase 2 (Tdp2)

Design and Synthesis of Chlorinated and Fluorinated 7‑Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I

Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors

Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[c]pyrrolo[2,3‑h][1,6]naphthyridin-5-one (BPN) Series

Analyzing the Influence of eWOM on Customer Perception of Value and Brand Love in Hospitality Enterprise

Synthesis of indolo[4,3-bc]phenanthridine-6,11(2H,12H)-diones using the schiff base-homophthalic anhydride cyclization reaction

Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitors

Isolation and characterization of Salmonella Enteritidis and Salmonella Typhimurium from chicken meat in Egypt

Service Value and Repurchase Intention in the Egyptian Fast-Food Restaurants: Toward a New Measurement Model

Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology

Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy

Discovery of 5‑Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors

Design, synthesis and molecular modeling study of certain 4-Methylbenzenesulfonamides with CDK2 inhibitory activity as anticancer and radio-sensitizing agents

Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors

Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitorsElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob02386c

Abstract 2662: Indenoisoquinoline topoisomerase I inhibitors target the DNA G-quadruplex formed in the c-Myc promoter and cause MYC downregulation

UNDERSTANDING THE INFLUENCE OF FOOD VALUE ON FAST-FOOD CUSTOMER BEHAVIOR: A STUDY ON THE MEDIATING ROLE OF BLOGGER REVIEWS AND MODERATING EFFECT OF CONTENT CREDIBILITY

CPAP for acute cardiogenic pulmonary oedema from out-of-hospital to cardiac intensive care unit: a randomised multicentre study

Design, Synthesis and Biological Evaluation of Some Topoisomerase Type 1 Poisons, Cox-2 Selective Agents, and Protein Kinase Inhibitors

Structure-based predictive model for some benzimidazole inhibitors of hepatitis C virus NS5B polymerase

Supramolecular Self‐Assembled Nanospheres for Enzyme Encapsulation Based on Cyclodextrin

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