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Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile

Journal of organic chemistry, 2012-05, Vol.77 (10), p.4732-4739

2012

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Synthesis and structural–activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4405-4409

2004

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3-Aminoquinazolinediones as a New Class of Antibacterial Agents Demonstrating Excellent Antibacterial Activity Against Wild-Type and Multidrug Resistant Organisms

Journal of medicinal chemistry, 2006-11, Vol.49 (22), p.6435-6438

2006

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Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3392-3397

2012

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Hydrozirconation-transmetalation. A mild, direct route to higher order vinylic cuprates from monosubstituted acetylenes

Journal of the American Chemical Society, 1990-09, Vol.112 (20), p.7440-7441

1990

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Structure–activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1312-1320

2007

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New methodology for conjugate additions of allylic ligands to .alpha.,.beta.-unsaturated ketones: synthetic and spectroscopic studies

Journal of the American Chemical Society, 1990-05, Vol.112 (11), p.4404-4410

1990

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Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones

Bioorganic & medicinal chemistry letters, 2008-09, Vol.18 (18), p.5087-5090

2008

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5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.843-858

2000

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Ligand exchange between cyanocuprates and allylic stannanes: a novel, direct route to allylic cuprates possessing remarkable reactivity and stability

Journal of the American Chemical Society, 1990-05, Vol.112 (10), p.4063-4064

1990

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Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3707-3711

1997

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4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3781-3792

1997

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Transmetalation reactions of higher order cyanocuprates: Direct formation of trialkyltin cuprates from tin hydrides which bypasses organolithium intermediates

Tetrahedron letters, 1989, Vol.30 (16), p.2065-2068

1989

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On the composition of Yamamoto's reagent: "RCu.cntdot.BF3"

Journal of the American Chemical Society, 1990-07, Vol.112 (15), p.5869-5871

1990

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Higher order cyanocuprates R2Cu(CN)Li2: discrete reagents or lower order lithium cyanide (LiCN) modified Gilman cuprates?

Journal of the American Chemical Society, 1990-05, Vol.112 (10), p.4032-4034

1990

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Synthesis of the novel antibacterial 6,8-dihydroxy-7-propyl-9H-pyrrolo[1,2-b][1,3]-benzoxazin-9-one

Tetrahedron letters, 2000-05, Vol.41 (21), p.4061-4064

2000

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Fine tuning the silicon-tin bond: transmetalations forming either trialkylstannyl or trialkylsilyl higher order cyanocuprates

Journal of organic chemistry, 1989-10, Vol.54 (21), p.4975-4977

1989

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Effects of boron trifluoride etherate on higher order organocuprate reactions: substrate activation or cuprate modification?

Journal of the American Chemical Society, 1988-07, Vol.110 (14), p.4834-4835

1988

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Understanding allylic organocuprates: .sigma.- or .pi.-bound reagents?

Journal of organic chemistry, 1989-10, Vol.54 (21), p.4977-4979

1989

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A facile synthesis of substituted 3-amino-1H-quinazoline-2,4-diones

Journal of heterocyclic chemistry, 2005-05, Vol.42 (4), p.669-674

2005

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Unexpected affects of Me3Si-X on reactions of higher order cyanocuprates

Tetrahedron letters, 1988, Vol.29 (51), p.6677-6680

1988

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Higher order cyanocuprates R2Cu(CN)Li2 : discrete reagents or lower order LiCN-modified gilman cuprates ?

Journal of the American Chemical Society, 1990-05, Vol.112 (10), p.4032-4034

1990

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Effects of gengenions on organocuprate reactivity/selectivity: Higher order, mixed lithio- [formula omitted] cyanocuprates

Tetrahedron letters, 1988, Vol.29 (8), p.893-896

1988

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A facile synthesis of substituted 3-amino-1 H -quinazoline-2,4-diones

Journal of heterocyclic chemistry, 2005-05, Vol.42 (4), p.669-674

2005

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Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2217-2222

1999

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Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile

Synthesis and structural–activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents

3-Aminoquinazolinediones as a New Class of Antibacterial Agents Demonstrating Excellent Antibacterial Activity Against Wild-Type and Multidrug Resistant Organisms

Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring

Hydrozirconation-transmetalation. A mild, direct route to higher order vinylic cuprates from monosubstituted acetylenes

Structure–activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors

New methodology for conjugate additions of allylic ligands to .alpha.,.beta.-unsaturated ketones: synthetic and spectroscopic studies

Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones

5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

Ligand exchange between cyanocuprates and allylic stannanes: a novel, direct route to allylic cuprates possessing remarkable reactivity and stability

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Transmetalation reactions of higher order cyanocuprates: Direct formation of trialkyltin cuprates from tin hydrides which bypasses organolithium intermediates

On the composition of Yamamoto's reagent: "RCu.cntdot.BF3"

Higher order cyanocuprates R2Cu(CN)Li2: discrete reagents or lower order lithium cyanide (LiCN) modified Gilman cuprates?

Synthesis of the novel antibacterial 6,8-dihydroxy-7-propyl-9H-pyrrolo[1,2-b][1,3]-benzoxazin-9-one

Fine tuning the silicon-tin bond: transmetalations forming either trialkylstannyl or trialkylsilyl higher order cyanocuprates

Effects of boron trifluoride etherate on higher order organocuprate reactions: substrate activation or cuprate modification?

Understanding allylic organocuprates: .sigma.- or .pi.-bound reagents?

A facile synthesis of substituted 3-amino-1H-quinazoline-2,4-diones

Unexpected affects of Me3Si-X on reactions of higher order cyanocuprates

Higher order cyanocuprates R2Cu(CN)Li2 : discrete reagents or lower order LiCN-modified gilman cuprates ?

Effects of gengenions on organocuprate reactivity/selectivity: Higher order, mixed lithio- [formula omitted] cyanocuprates

A facile synthesis of substituted 3-amino-1 H -quinazoline-2,4-diones

Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

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