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Aged‐senescent cells contribute to impaired heart regeneration

Aging cell, 2019-06, Vol.18 (3), p.e12931-n/a

2019

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First evidence that senolytics are effective at decreasing senescent cells in humans

EBioMedicine, 2020-06, Vol.56, p.102473-102473, Article 102473

Ellison-Hughes, Georgina M.

2020

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Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age

Diabetes (New York, N.Y.), 2022-05, Vol.71 (5), p.1081-1098

2022

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Transplantation of Skeletal Muscle-Derived Sca-1 + /PW1 + /Pax7 - Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction

Cells (Basel, Switzerland), 2022-12, Vol.11 (24), p.4050

2022

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Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease

Cells (Basel, Switzerland), 2020-06, Vol.9 (6), p.1558

2020

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Imatinib Mesylate Induces Necroptotic Cell Death and Impairs Autophagic Flux in Human Cardiac Progenitor Cells

International journal of molecular sciences, 2022-10, Vol.23 (19), p.11812

2022

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Vascular Manifestations of COVID-19 - Thromboembolism and Microvascular Dysfunction

Frontiers in cardiovascular medicine, 2020-10, Vol.7, p.598400

2020

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Senescent Cells: A Therapeutic Target in Cardiovascular Diseases

Cells (Basel, Switzerland), 2023-05, Vol.12 (9), p.1296

2023

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Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells

Scientific reports, 2022-06, Vol.12 (1), p.10132-10132, Article 10132

2022

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c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

Cell death & disease, 2019-06, Vol.10 (6), p.436, Article 436

2019

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Cardiac Stem Cells for Myocardial Regeneration: They Are Not Alone

Frontiers in cardiovascular medicine, 2017-07, Vol.4, p.47-47

2017

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Correction: c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

Cell death & disease, 2023-04, Vol.14 (4), p.266-266, Article 266

2023

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The Role of MSC Therapy in Attenuating the Damaging Effects of the Cytokine Storm Induced by COVID-19 on the Heart and Cardiovascular System

Frontiers in cardiovascular medicine, 2020-12, Vol.7, p.602183

2020

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A protocol for extracting immunolabeled murine cardiomyocytes of high-quality RNA by laser capture microdissection

STAR protocols, 2022-03, Vol.3 (1), p.101231-101231, Article 101231

2022

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Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery

Pharmacology & therapeutics (Oxford), 2017-03, Vol.171, p.1-12

2017

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Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo

Stem cell research & therapy, 2017-07, Vol.8 (1), p.158-158, Article 158

2017

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Targeting Cell Senescence to Improve Cardiac Regeneration

Texas Heart Institute journal, 2023-10, Vol.50 (5)

Ellison-Hughes, Georgina M.

2023

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Correction: Ruchaya et al. Transplantation of Skeletal Muscle-Derived Sca-1 + /PW1 + /Pax7 - Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction. Cells 2022 , 11 , 4050

Cells (Basel, Switzerland), 2024-05, Vol.13 (11), p.895

2024

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Senescent cells: targeting and therapeutic potential of senolytics in age-related diseases with a particular focus on the heart

Expert opinion on therapeutic targets, 2020-09, Vol.24 (9), p.819-823

Ellison-Hughes, Georgina M.

2020

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Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

Cell death and differentiation, 2017-12, Vol.24 (12), p.2101-2116

2017

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Editorial commentary: The cardiac regeneration interchange

Trends in cardiovascular medicine, 2020-08, Vol.30 (6), p.344-345

2020

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A Mouse Model of Dilated Cardiomyopathy Produced by Isoproterenol Acute Exposure Followed by 5-Fluorouracil Administration

Journal of cardiovascular development and disease, 2023-05, Vol.10 (6), p.225

2023

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Human primary skeletal muscle‐derived myoblasts and fibroblasts reveal different senescent phenotypes

JCSM rapid communications, 2022-07, Vol.5 (2), p.226-238

2022

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Atrial myxomas arise from multipotent cardiac stem cells

European heart journal, 2020-12, Vol.41 (45), p.4332-4345

2020

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Transplantation of Allogeneic PW1pos /Pax7neg Interstitial Cells Enhance Endogenous Repair of Injured Porcine Skeletal Muscle

JACC. Basic to translational science, 2017-12, Vol.2 (6), p.717-736

2017

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Aged‐senescent cells contribute to impaired heart regeneration

First evidence that senolytics are effective at decreasing senescent cells in humans

Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age

Transplantation of Skeletal Muscle-Derived Sca-1 + /PW1 + /Pax7 - Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction

Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease

Imatinib Mesylate Induces Necroptotic Cell Death and Impairs Autophagic Flux in Human Cardiac Progenitor Cells

Vascular Manifestations of COVID-19 - Thromboembolism and Microvascular Dysfunction

Senescent Cells: A Therapeutic Target in Cardiovascular Diseases

Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells

c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

Cardiac Stem Cells for Myocardial Regeneration: They Are Not Alone

Correction: c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

The Role of MSC Therapy in Attenuating the Damaging Effects of the Cytokine Storm Induced by COVID-19 on the Heart and Cardiovascular System

A protocol for extracting immunolabeled murine cardiomyocytes of high-quality RNA by laser capture microdissection

Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery

Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo

Targeting Cell Senescence to Improve Cardiac Regeneration

Correction: Ruchaya et al. Transplantation of Skeletal Muscle-Derived Sca-1 + /PW1 + /Pax7 - Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction. Cells 2022 , 11 , 4050

Senescent cells: targeting and therapeutic potential of senolytics in age-related diseases with a particular focus on the heart

Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

Editorial commentary: The cardiac regeneration interchange

A Mouse Model of Dilated Cardiomyopathy Produced by Isoproterenol Acute Exposure Followed by 5-Fluorouracil Administration

Human primary skeletal muscle‐derived myoblasts and fibroblasts reveal different senescent phenotypes

Atrial myxomas arise from multipotent cardiac stem cells

Transplantation of Allogeneic PW1pos /Pax7neg Interstitial Cells Enhance Endogenous Repair of Injured Porcine Skeletal Muscle

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