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BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Journal of medicinal chemistry, 2000-09, Vol.43 (19), p.3482-3486

2000

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Systematic Structure-Based Design and Stereoselective Synthesis of Novel Multisubstituted Cyclopentane Derivatives with Potent Antiinfluenza Activity

Journal of medicinal chemistry, 2001-12, Vol.44 (25), p.4379-4392

2001

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Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

Journal of medicinal chemistry, 1985-07, Vol.28 (7), p.876-892

1985

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An Improved Synthesis of 7-Substituted Pyrrolo[3,2- d ]pyrimidines

Journal of organic chemistry, 1997-11, Vol.62 (23), p.8071-8075

1997

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Synthesis and Biological Activity of a Novel Class of Purine Nucleoside Phosphorylase Inhibitors

Nucleosides, nucleotides & nucleic acids, 2000-01, Vol.19 (1-2), p.379-404

2000

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Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogs

Journal of medicinal chemistry, 1989-08, Vol.32 (8), p.1686-1700

1989

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Isobenzofurans as conformationally constrained miconazole analogs with improved antifungal potency

Journal of medicinal chemistry, 1992-10, Vol.35 (22), p.4221-4229

1992

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Antiulcer agents. 3. Structure-activity-toxicity relationships of substituted imidazo[1,2-a]pyridines and a related imidazo[1,2-a]pyrazine

Journal of medicinal chemistry, 1987-11, Vol.30 (11), p.2047-2051

1987

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Antiulcer agents. 2. Gastric antisecretory, cytoprotective, and metabolic properties of substituted imidazo[1,2-a]pyridines and analogs

Journal of medicinal chemistry, 1987-11, Vol.30 (11), p.2031-2046

1987

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The Rearrangement of Aryl Thiohydrazonates

Canadian journal of chemistry, 1975-05, Vol.53 (10), p.1484-1490

1975

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Hydrazides and thiohydrazides as sources of condensed oxadiazines and thiadiazines, including novel azo derivatives based on dithizone

Journal of organic chemistry, 1980-08, Vol.45 (18), p.3677-3681

1980

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Central nervous system activity of 7-substituted 1-azaphenoxathiin analogs and their oxidation products

Journal of medicinal chemistry, 1980-03, Vol.23 (3), p.333-335

1980

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Synthesis of some 5-phenylhexahydroazepino[4,5-b]indoles as potential neuroleptic agents

Journal of medicinal chemistry, 1980-11, Vol.23 (11), p.1268-1269

1980

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A short, facile synthesis of 2-amino-1,5-dihydro-4H-pyrrolo[3,2- d]-pyrimidin-4-one (9-Deazaguanine)

Tetrahedron letters, 1996-06, Vol.37 (25), p.4339-4340

1996

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Cyclization of Some 2,3,5,6-Tetrafluorophenylhydrazine Derivatives. Use of Nuclear Overhauser Effect Measurements in Structural Assignment

Canadian journal of chemistry, 1975-09, Vol.53 (17), p.2534-2536

1975

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New syntheses of 7-substituted-2-aminothieno- and furo[3,2-d]pyrimidines

Journal of heterocyclic chemistry, 1999-03, Vol.36 (2), p.423-427

1999

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Mesoionic compounds. XXXVIII. The anhydro-2-aryl-1,3-dithiolium hydroxide system

Journal of organic chemistry, 1976-05, Vol.41 (10), p.1724-1728

1976

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Synthesis of pyrrolo[3,2-d]pyrimidines (9-deazaguanines) by reductive cyclodeamination reactions

Tetrahedron letters, 1996-08, Vol.37 (33), p.5829-5830

1996

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Unusual reaction of 4-mercapto-1,2,3-benzotriazine with N-(2,4-dibromophenyl)benzohydrazonyl bromide

Journal of organic chemistry, 1975-07, Vol.40 (14), p.2131-2131

1975

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trans-Reduction of 5-phenyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole. X-Ray crystallographic study of the geometry of an intermolecular N–H ⋯ phenyl hydrogen bond

J. Chem. Soc., Perkin Trans. 2, 1983 (9), p.1599-1603

1983

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Reaction of dehydrodithizone with benzyne and diphenylcyclopropenethione. Isolation of N-(1,2-diphenyldiazonia)-1,3-benzothiazole-2-aminate and the formation of 2-phenylazo-4,6,7-triphenyl-4H-1,3,4-thiadiazepine-5-thione

Journal of the Chemical Society, Perkin Transactions 1, 1981, p.2692

1981

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Acylation of N′-arylbenzothiohydrazides and of their N′-acyl-derivatives; 2-acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes and related compounds

J. Chem. Soc., Perkin Trans. 1, 1981, p.2948-2951

1981

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Synthesis of 1H-4,1,2-benzothiadiazines from substituted N-acetyl-N-aryl-N′-thioaroylhydrazines

J. Chem. Soc., Perkin Trans. 1, 1975 (14), p.1386-1390

1975

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Reactions of benzothiohydrazide as a bidentate nucleophile

Journal of heterocyclic chemistry, 1981-06, Vol.18 (4), p.799-800

Elliott, Arthur J.

1981

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On the reaction of 2-aminopyridines with alpha-halocarbonyl compounds

Journal of heterocyclic chemistry, 1982-11, Vol.19 (6), p.1437-1440

1982

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BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Systematic Structure-Based Design and Stereoselective Synthesis of Novel Multisubstituted Cyclopentane Derivatives with Potent Antiinfluenza Activity

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

An Improved Synthesis of 7-Substituted Pyrrolo[3,2- d ]pyrimidines

Synthesis and Biological Activity of a Novel Class of Purine Nucleoside Phosphorylase Inhibitors

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogs

Isobenzofurans as conformationally constrained miconazole analogs with improved antifungal potency

Antiulcer agents. 3. Structure-activity-toxicity relationships of substituted imidazo[1,2-a]pyridines and a related imidazo[1,2-a]pyrazine

Antiulcer agents. 2. Gastric antisecretory, cytoprotective, and metabolic properties of substituted imidazo[1,2-a]pyridines and analogs

The Rearrangement of Aryl Thiohydrazonates

Hydrazides and thiohydrazides as sources of condensed oxadiazines and thiadiazines, including novel azo derivatives based on dithizone

Central nervous system activity of 7-substituted 1-azaphenoxathiin analogs and their oxidation products

Synthesis of some 5-phenylhexahydroazepino[4,5-b]indoles as potential neuroleptic agents

A short, facile synthesis of 2-amino-1,5-dihydro-4H-pyrrolo[3,2- d]-pyrimidin-4-one (9-Deazaguanine)

Cyclization of Some 2,3,5,6-Tetrafluorophenylhydrazine Derivatives. Use of Nuclear Overhauser Effect Measurements in Structural Assignment

New syntheses of 7-substituted-2-aminothieno- and furo[3,2-d]pyrimidines

Mesoionic compounds. XXXVIII. The anhydro-2-aryl-1,3-dithiolium hydroxide system

Synthesis of pyrrolo[3,2-d]pyrimidines (9-deazaguanines) by reductive cyclodeamination reactions

Unusual reaction of 4-mercapto-1,2,3-benzotriazine with N-(2,4-dibromophenyl)benzohydrazonyl bromide

trans-Reduction of 5-phenyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole. X-Ray crystallographic study of the geometry of an intermolecular N–H ⋯ phenyl hydrogen bond

Reaction of dehydrodithizone with benzyne and diphenylcyclopropenethione. Isolation of N-(1,2-diphenyldiazonia)-1,3-benzothiazole-2-aminate and the formation of 2-phenylazo-4,6,7-triphenyl-4H-1,3,4-thiadiazepine-5-thione

Acylation of N′-arylbenzothiohydrazides and of their N′-acyl-derivatives; 2-acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes and related compounds

Synthesis of 1H-4,1,2-benzothiadiazines from substituted N-acetyl-N-aryl-N′-thioaroylhydrazines

Reactions of benzothiohydrazide as a bidentate nucleophile

On the reaction of 2-aminopyridines with alpha-halocarbonyl compounds

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