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Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49164-49170

2003

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Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.11979-11984

2003

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A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties

Antimicrobial Agents and Chemotherapy, 2004-10, Vol.48 (10), p.3944-3953

2004

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Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

Journal of medicinal chemistry, 2004-10, Vol.47 (21), p.5284-5297

2004

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Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

Journal of medicinal chemistry, 2004-04, Vol.47 (9), p.2283-2295

2004

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Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5864-5868

2009

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Inhibitory Effect of 2′-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

Antimicrobial Agents and Chemotherapy, 2005-05, Vol.49 (5), p.2050-2058

2005

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Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.571-575

2010

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Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.2177-2180

2013

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Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3703-3707

2010

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Substituted 1,8-Naphthyridin-2(1H)-ones Are Superior to Thymine in the Recognition of Adenine in Duplex as Well as Triplex Structures

Journal of the American Chemical Society, 2002-04, Vol.124 (13), p.3254-3262

2002

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Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing

Nucleic acids research, 2004, Vol.32 (9), p.2695

2004

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Synthesis and Evaluation of S-Acyl-2-thioethyl Esters of Modified Nucleoside 5‘-Monophosphates as Inhibitors of Hepatitis C Virus RNA Replication

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.1199-1210

2005

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Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6741-6749

2005

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1,8-Naphthyridin-2(1H)-ones − Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs)

European journal of organic chemistry, 2001-05, Vol.2001 (9), p.1781-1790

2001

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A Novel Peptide Nucleic Acid Monomer for Recognition of Thymine in Triple-Helix Structures

Journal of the American Chemical Society, 1997-11, Vol.119 (45), p.11116-11117

1997

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1,8-Naphthyridin-2,7-( 1,8H)-dione is an effective mimic of protonated cytosine in peptide nucleic acid triplex recognition systems

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3121-3124

2002

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Synthesis and biological evaluation of 5R- and 5S-methyl substituted d- and l-configuration 1,3-dioxolane nucleoside analogs

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (23), p.6237-6247

2004

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The first example of a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine

Perkin 1 : an international journal of organic and bio-organic chemistry, 2001 (14), p.1656-1661

2001

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A high‐throughput fluorescence polarization assay for the determination of Kd for soluble epoxide hydrolase inhibitors

The FASEB journal, 2008-03, Vol.22 (S1)

2008

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Inhibition of Hepatitis C Virus RNA Replication by 2â²-Modified Nucleoside Analogs

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.11979

2003

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Preparation of oligodeoxyribonucleoside phosphoro-dithioates by a triester method

Nucleic acids research, 1994-05, Vol.22 (10), p.1797-1804

1994

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New solid phase synthesis of oligodeoxythymidine phosphorodithioates by a modified HObt-method

Tetrahedron letters, 1995-08, Vol.36 (34), p.6127-6130

1995

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ChemInform Abstract: Peptide Nucleic Acids: Potential as Antisense and Antigene Drugs

ChemInform, 2000-04, Vol.31 (15), p.no-no

2000

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Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro

Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs

A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties

Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase

Inhibitory Effect of 2′-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase

Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists

Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method

Substituted 1,8-Naphthyridin-2(1H)-ones Are Superior to Thymine in the Recognition of Adenine in Duplex as Well as Triplex Structures

Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing

Synthesis and Evaluation of S-Acyl-2-thioethyl Esters of Modified Nucleoside 5‘-Monophosphates as Inhibitors of Hepatitis C Virus RNA Replication

Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

1,8-Naphthyridin-2(1H)-ones − Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs)

A Novel Peptide Nucleic Acid Monomer for Recognition of Thymine in Triple-Helix Structures

1,8-Naphthyridin-2,7-( 1,8H)-dione is an effective mimic of protonated cytosine in peptide nucleic acid triplex recognition systems

Synthesis and biological evaluation of 5R- and 5S-methyl substituted d- and l-configuration 1,3-dioxolane nucleoside analogs

The first example of a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine

A high‐throughput fluorescence polarization assay for the determination of Kd for soluble epoxide hydrolase inhibitors

Inhibition of Hepatitis C Virus RNA Replication by 2â²-Modified Nucleoside Analogs

Preparation of oligodeoxyribonucleoside phosphoro-dithioates by a triester method

New solid phase synthesis of oligodeoxythymidine phosphorodithioates by a modified HObt-method

ChemInform Abstract: Peptide Nucleic Acids: Potential as Antisense and Antigene Drugs

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