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Liver Hypertrophy: A Review of Adaptive (Adverse and Non-adverse) Changes—Conclusions from the 3rd International ESTP Expert Workshop

Toxicologic pathology, 2012-10, Vol.40 (7), p.971-994

2012

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Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis

Human & experimental toxicology, 1994-11, Vol.13 (2_suppl), p.S1-S117

1994

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Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats

Toxicology (Amsterdam), 2003-02, Vol.183 (1), p.117-131

2003

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Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

Biochemical journal, 2002-07, Vol.365 (Pt 2), p.405-416

2002

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Biochemical mechanisms of induction of hepatic peroxisome proliferation

Annual review of pharmacology and toxicology, 1989-01, Vol.29 (1), p.145-163

1989

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The effect of chlorinated paraffins on hepatic enzymes and thyroid hormones

Toxicology (Amsterdam), 1993-01, Vol.77 (1), p.81-90

1993

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Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes

Toxicology (Amsterdam), 2005-06, Vol.210 (2), p.147-157

2005

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A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey ( Macaca fascicularis), human, mouse, rat and hamster liver microsomes

Biochemical pharmacology, 1994-03, Vol.47 (5), p.763-773

1994

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Peroxisome Proliferation due to Di(2-Ethylhexyl) Phthalate (DEHP): Species Differences and Possible Mechanisms

Environmental health perspectives, 1986-12, Vol.70, p.211-219

1986

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Species-specific induction of cytochrome P-450 4A RNAs : PCR cloning to partial guinea-pig, human and mouse CYP4A cDNAs

Biochemical journal, 1993-08, Vol.294 (1), p.173-180

1993

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Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

Biochemical journal, 2003-07, Vol.373 (Pt 2), p.559-569

2003

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Localization and differential induction of cytochrome P450IVA and acyl-CoA oxidase in rat liver

Biochemical journal, 1991-04, Vol.275 (1), p.247-252

1991

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Prediction of Rodent Nongenotoxic Carcinogenesis: Evaluation of Biochemical and Tissue Changes in Rodents Following Exposure to Nine Nongenotoxic NTP Carcinogens

Environmental health perspectives, 2002-04, Vol.110 (4), p.363-375

2002

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The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate

Carcinogenesis (New York), 1998-09, Vol.19 (9), p.1521-1527

1998

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Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

Critical reviews in toxicology, 2014-01, Vol.44 (1), p.64-82

2014

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Dose-dependent acinar induction of cytochromes P450 in rat liver : evidence for a differential mechanism of induction of P450IA1 by β-naphthoflavone and dioxin

Biochemical journal, 1991-07, Vol.277 (2), p.577-580

1991

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The peroxisome proliferators are hepatocyte mitogens in chemically-defined media : glucocorticoid-induced PPARα is linked to peroxisome proliferator mitogenesis

Carcinogenesis (New York), 1998-05, Vol.19 (5), p.925-931

1998

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Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators

Biochemical journal, 1991-11, Vol.280 ( Pt 1) (1), p.249-253

1991

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Evaluation of phenobarbital/β-naphthoflavone as an alternative S9-induction regime to Aroclor 1254 in the rat for use in in vitro genotoxicity assays

Mutagenesis, 1995-11, Vol.10 (6), p.517-522

1995

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Induction of cytochrome P-450 in cultured rat hepatocytes. The heterogeneous localization of specific isoenzymes using immunocytochemistry

Biochemical journal, 1989-08, Vol.262 (1), p.151-158

1989

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Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators

Carcinogenesis (New York), 1987-09, Vol.8 (9), p.1213-1218

1987

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Identification of the proximate peroxisome proliferator(S) derived from DI (2-ethylhexyl) adipate and species differences in response

Biochemical pharmacology, 1992-05, Vol.43 (10), p.2129-2134

1992

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Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

Biochemical pharmacology, 1985-09, Vol.34 (18), p.3337-3345

1985

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Peroxisome proliferation due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid

Archives of toxicology, 1992-05, Vol.66 (5), p.321-326

1992

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Placental transfer of the hypolipidemic drug, clofibrate, induces CYP4A expression in 18.5-day fetal rats

Drug metabolism and disposition, 1996-05, Vol.24 (5), p.547

1996

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Liver Hypertrophy: A Review of Adaptive (Adverse and Non-adverse) Changes—Conclusions from the 3rd International ESTP Expert Workshop

Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis

Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

Biochemical mechanisms of induction of hepatic peroxisome proliferation

The effect of chlorinated paraffins on hepatic enzymes and thyroid hormones

Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes

A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey ( Macaca fascicularis), human, mouse, rat and hamster liver microsomes

Peroxisome Proliferation due to Di(2-Ethylhexyl) Phthalate (DEHP): Species Differences and Possible Mechanisms

Species-specific induction of cytochrome P-450 4A RNAs : PCR cloning to partial guinea-pig, human and mouse CYP4A cDNAs

Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

Localization and differential induction of cytochrome P450IVA and acyl-CoA oxidase in rat liver

Prediction of Rodent Nongenotoxic Carcinogenesis: Evaluation of Biochemical and Tissue Changes in Rodents Following Exposure to Nine Nongenotoxic NTP Carcinogens

The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

Dose-dependent acinar induction of cytochromes P450 in rat liver : evidence for a differential mechanism of induction of P450IA1 by β-naphthoflavone and dioxin

The peroxisome proliferators are hepatocyte mitogens in chemically-defined media : glucocorticoid-induced PPARα is linked to peroxisome proliferator mitogenesis

Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators

Evaluation of phenobarbital/β-naphthoflavone as an alternative S9-induction regime to Aroclor 1254 in the rat for use in in vitro genotoxicity assays

Induction of cytochrome P-450 in cultured rat hepatocytes. The heterogeneous localization of specific isoenzymes using immunocytochemistry

Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators

Identification of the proximate peroxisome proliferator(S) derived from DI (2-ethylhexyl) adipate and species differences in response

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

Peroxisome proliferation due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid

Placental transfer of the hypolipidemic drug, clofibrate, induces CYP4A expression in 18.5-day fetal rats

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