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Widespread Activation of Calcium-Activated Neutral Proteinase (Calpain) in the Brain in Alzheimer Disease: A Potential Molecular Basis for Neuronal Degeneration

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (7), p.2628-2632

1993

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v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation

Molecular and Cellular Biology, 2002-01, Vol.22 (1), p.257-269

2002

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Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart

Circulation (New York, N.Y.), 1993-02, Vol.87 (2), p.454-463

1993

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Disruption of the Murine Calpain Small Subunit Gene, Capn4: Calpain Is Essential for Embryonic Development but Not for Cell Growth and Division

Molecular and Cellular Biology, 2000-06, Vol.20 (12), p.4474-4481

2000

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Reduced Cell Migration and Disruption of the Actin Cytoskeleton in Calpain-deficient Embryonic Fibroblasts

The Journal of biological chemistry, 2001-12, Vol.276 (51), p.48382-48388

2001

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A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein

Proteins, structure, function, and bioinformatics, 2003-11, Vol.53 (3), p.649-655

2003

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Calpains Mediate p53 Activation and Neuronal Death Evoked by DNA Damage

The Journal of biological chemistry, 2003-07, Vol.278 (28), p.26031-26038

2003

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Dissociation and Aggregation of Calpain in the Presence of Calcium

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.47233-47238

2001

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Active recombinant rat calpain II. Bacterially produced large and small subunits associate both in vivo and in vitro

The Journal of biological chemistry, 1994-12, Vol.269 (48), p.30457-30460

1994

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Calpain activation is upstream of caspases in radiation-induced apoptosis

Cell death and differentiation, 1998-12, Vol.5 (12), p.1051-1061

1998

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Expression of m-calpain in Escherichia coli

Methods in molecular biology (Clifton, N.J.), 2000, Vol.144, p.47

Elce, J S

2000

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Autolysis, Ca2+ Requirement, and Heterodimer Stability in m-Calpain

The Journal of biological chemistry, 1997-04, Vol.272 (17), p.11268-11275

1997

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Purification, characterization, and N-terminal amino acid sequence of the adenylyl cyclase-activating protease from bovine sperm

Biology of reproduction, 1995-03, Vol.52 (3), p.490-499

1995

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Mutations in Calpain 3 Associated with Limb Girdle Muscular Dystrophy: Analysis by Molecular Modeling and by Mutation in m-Calpain

Biophysical journal, 2001-06, Vol.80 (6), p.2590-2596

2001

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Constitutive expression of calpain II in the rat uterus during pregnancy and involution

Biochemical journal, 1991-06, Vol.276 (2), p.293-299

1991

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Oxidation Inhibits Substrate Proteolysis by Calpain I but Not Autolysis

The Journal of biological chemistry, 1997-01, Vol.272 (3), p.2005-2012

1997

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Roles of individual EF-hands in the activation of m-calpain by calcium

Biochemical journal, 2000-05, Vol.348 Pt 1 (1), p.37-43

2000

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Calpain I remains intact and intracellular during platelet activation. Immunochemical measurements with monoclonal and polyclonal antibodies

Biochemical journal, 1987-09, Vol.246 (2), p.481-488

1987

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Purification and functional characterization of β-adrenergic receptor kinase expressed in insect cells

FEBS letters, 1993-06, Vol.324 (1), p.59-62

1993

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Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation

The EMBO journal, 1999-12, Vol.18 (24), p.6880-6889

1999

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Immunogold electron-microscopic localization of calpain I in human erythrocytes

Thrombosis and haemostasis, 1989-04, Vol.61 (2), p.250-253

1989

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The effects of truncations of the small subunit on m-calpain activity and heterodimer formation

Biochemical journal, 1997-08, Vol.326 ( Pt 1) (1), p.31-38

1997

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Calpain I activation is not correlated with aggregation in human platelets

Biochemical journal, 1989-08, Vol.261 (3), p.1039-1042

1989

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Immunofluorescent localization of a Ca2+-dependent neutral protease in hamster muscle

American journal of physiology: endocrinology and metabolism, 1981-05, Vol.240 (5), p.E493-E498

1981

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Fluorescence measurements of Ca2+ binding to domain VI of calpain

Methods in molecular biology (Clifton, N.J.), 2000, Vol.144, p.121

2000

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Widespread Activation of Calcium-Activated Neutral Proteinase (Calpain) in the Brain in Alzheimer Disease: A Potential Molecular Basis for Neuronal Degeneration

v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart

Disruption of the Murine Calpain Small Subunit Gene, Capn4: Calpain Is Essential for Embryonic Development but Not for Cell Growth and Division

Reduced Cell Migration and Disruption of the Actin Cytoskeleton in Calpain-deficient Embryonic Fibroblasts

A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein

Calpains Mediate p53 Activation and Neuronal Death Evoked by DNA Damage

Dissociation and Aggregation of Calpain in the Presence of Calcium

Active recombinant rat calpain II. Bacterially produced large and small subunits associate both in vivo and in vitro

Calpain activation is upstream of caspases in radiation-induced apoptosis

Expression of m-calpain in Escherichia coli

Autolysis, Ca2+ Requirement, and Heterodimer Stability in m-Calpain

Purification, characterization, and N-terminal amino acid sequence of the adenylyl cyclase-activating protease from bovine sperm

Mutations in Calpain 3 Associated with Limb Girdle Muscular Dystrophy: Analysis by Molecular Modeling and by Mutation in m-Calpain

Constitutive expression of calpain II in the rat uterus during pregnancy and involution

Oxidation Inhibits Substrate Proteolysis by Calpain I but Not Autolysis

Roles of individual EF-hands in the activation of m-calpain by calcium

Calpain I remains intact and intracellular during platelet activation. Immunochemical measurements with monoclonal and polyclonal antibodies

Purification and functional characterization of β-adrenergic receptor kinase expressed in insect cells

Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation

Immunogold electron-microscopic localization of calpain I in human erythrocytes

The effects of truncations of the small subunit on m-calpain activity and heterodimer formation

Calpain I activation is not correlated with aggregation in human platelets

Immunofluorescent localization of a Ca2+-dependent neutral protease in hamster muscle

Fluorescence measurements of Ca2+ binding to domain VI of calpain

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