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Novel promising benzoxazole/benzothiazole‐derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis

Archiv der Pharmazie (Weinheim), 2023-09, Vol.356 (9), p.e2300097-n/a

2023

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Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

RSC advances, 2023-07, Vol.13 (32), p.22122-22147

2023

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Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

RSC advances, 2022-11, Vol.12 (52), p.33525-33539

2022

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Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.573-591

2022

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Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies

Molecules (Basel, Switzerland), 2022-09, Vol.27 (19), p.6203

2022

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Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

RSC advances, 2023-04, Vol.13 (16), p.10488-10502

2023

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Design, Synthesis, Molecular Modeling and Anti-Hyperglycemic Evaluation of Quinazoline-Sulfonylurea Hybrids as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Sulfonylurea Receptor (SUR) Agonists

International journal of molecular sciences, 2022-08, Vol.23 (17), p.9605

2022

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Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs

International journal of molecular sciences, 2023-08, Vol.24 (15), p.12416

2023

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Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents

Bioorganic chemistry, 2020-11, Vol.104, p.104218, Article 104218

2020

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Immunomodulatory quinazoline-based thalidomide analogs: Design, synthesis, apoptosis and anticancer evaluations

Journal of molecular structure, 2023-06, Vol.1281, p.135164, Article 135164

2023

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Design, synthesis, anticancer evaluation, in silico docking and ADMET analysis of novel indole-based thalidomide analogs as promising immunomodulatory agents

Journal of biomolecular structure & dynamics, 2023-12, Vol.41 (24), p.15106-15123

2023

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Design, synthesis and biological evaluation of newly triazolo-quinoxaline based potential immunomodulatory anticancer molecules

Journal of molecular structure, 2024-02, Vol.1298, p.137041, Article 137041

2024

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Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of phthalimide-sulfonylurea hybrids as PPARγ and SUR agonists

Bioorganic chemistry, 2019-10, Vol.91, p.103115, Article 103115

2019

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New immunomodulatory anticancer quinazolinone-based thalidomide analogs: design, synthesis and biological evaluation

Future medicinal chemistry, 2024-11, p.1-11

2024

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Biological and computational assessment of new synthesized nicotinamides as potential immunomodulatory VEGFR-2 inhibitors

Journal of molecular structure, 2024-06, Vol.1305, p.137753, Article 137753

2024

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Immunomodulation and anticancer evaluation of quinazoline-based thalidomide analogs: Design, synthesis, docking, and dynamic simulation

Journal of molecular structure, 2024-12, Vol.1317, p.139082, Article 139082

2024

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Design, synthesis and molecular modeling of new quinazolin-4(3H)-one based VEGFR-2 kinase inhibitors for potential anticancer evaluation

Bioorganic chemistry, 2021-04, Vol.109, p.104695-104695, Article 104695

2021

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Design, synthesis, studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

RSC advances, 2023-07, Vol.13 (32), p.22122-22147

2023

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New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies

Journal of biomolecular structure & dynamics, 2023-12, p.1-18

2023

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Design, synthesis, anticancer evaluation, and ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

RSC advances, 2023-04, Vol.13 (16), p.1488-152

2023

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AN OVERVIEW OF QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS

Al-Azhar Journal of Pharmaceutical Sciences, 2023-09, Vol.68 (2), p.130-158

2023

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PYRIDINE DERIVATIVES AS ANTICANCER AGENTS: FDA-APPROVED DRUGS AND PROMISING REPORTED COMPOUNDS

Al-Azhar Journal of Pharmaceutical Sciences, 2023-09, Vol.68 (2), p.64-81

2023

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EXPLORING THE PROTEIN KINASE INHIBITORY ACTIVITY OF QUINAZOLINES AS ANTICANCER AGENTS: FDA-APPROVED DRUGS AND PROMISING REPORTED COMPOUNDS

Al-Azhar Journal of Pharmaceutical Sciences, 2023-09, Vol.68 (2), p.82-110

2023

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DUAL INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) AND TRYPTOPHAN-2,3-DIOXYGENASE (TDO) AS ANTI-TUMOR IMMUNE MODULATORS

Al-Azhar Journal of Pharmaceutical Sciences, 2024-03, Vol.69 (1), p.38-61

2024

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Effective Management of Acute Aluminum Phosphide Poisoning in Pregnancy: A Case Study of Dual Therapy Efficacy and Collaborative Care

Journal of the Medical Research Institute, 2024-06, Vol.45 (2), p.1-4

2024

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Novel promising benzoxazole/benzothiazole‐derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis

Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors

Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies

Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

Design, Synthesis, Molecular Modeling and Anti-Hyperglycemic Evaluation of Quinazoline-Sulfonylurea Hybrids as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Sulfonylurea Receptor (SUR) Agonists

Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs

Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents

Immunomodulatory quinazoline-based thalidomide analogs: Design, synthesis, apoptosis and anticancer evaluations

Design, synthesis, anticancer evaluation, in silico docking and ADMET analysis of novel indole-based thalidomide analogs as promising immunomodulatory agents

Design, synthesis and biological evaluation of newly triazolo-quinoxaline based potential immunomodulatory anticancer molecules

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of phthalimide-sulfonylurea hybrids as PPARγ and SUR agonists

New immunomodulatory anticancer quinazolinone-based thalidomide analogs: design, synthesis and biological evaluation

Biological and computational assessment of new synthesized nicotinamides as potential immunomodulatory VEGFR-2 inhibitors

Immunomodulation and anticancer evaluation of quinazoline-based thalidomide analogs: Design, synthesis, docking, and dynamic simulation

Design, synthesis and molecular modeling of new quinazolin-4(3H)-one based VEGFR-2 kinase inhibitors for potential anticancer evaluation

Design, synthesis, studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies

Design, synthesis, anticancer evaluation, and ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

AN OVERVIEW OF QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS

PYRIDINE DERIVATIVES AS ANTICANCER AGENTS: FDA-APPROVED DRUGS AND PROMISING REPORTED COMPOUNDS

EXPLORING THE PROTEIN KINASE INHIBITORY ACTIVITY OF QUINAZOLINES AS ANTICANCER AGENTS: FDA-APPROVED DRUGS AND PROMISING REPORTED COMPOUNDS

DUAL INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) AND TRYPTOPHAN-2,3-DIOXYGENASE (TDO) AS ANTI-TUMOR IMMUNE MODULATORS

Effective Management of Acute Aluminum Phosphide Poisoning in Pregnancy: A Case Study of Dual Therapy Efficacy and Collaborative Care

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