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Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast

Clinical pharmacology and therapeutics, 2017-03, Vol.101 (3), p.406-415

2017

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Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters

Clinical pharmacology and therapeutics, 2017-07, Vol.102 (1), p.33-36

2017

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Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations

Clinical pharmacology and therapeutics, 2016-11, Vol.100 (5), p.419-422

2016

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The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems

International journal of pharmaceutics, 2000-04, Vol.198 (2), p.179-189

2000

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Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine) hexahydro-1H-azepine-2-one as dermal penetration enhancers : side chain length variation and molecular modeling

Journal of controlled release, 2001-06, Vol.73 (2-3), p.183-196

2001

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The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities

International journal of pharmaceutics, 2001-03, Vol.215 (1), p.229-240

2001

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Effect of Formulation Variables on the Percutaneous Permeation of Ketoprofen from Gel Formulations

Drug delivery, 2000, Vol.7 (3), p.147-153

2000

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Enhancement of transdermal drug delivery: chemical and physical approaches

Critical reviews in therapeutic drug carrier systems, 2000, Vol.17 (6), p.621

2000

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Preparation of Amino nictino nitril and its application as corrosion inhibitor for carbon steel

Journal of Basic and Environmental Sciences, 2017-07, Vol.4 (3), p.226-235

2017

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GIT Anatomy and Physiology and Drug Oral Bioavailability: Impact of Species Differences

Oral Bioavailability Assessment, 2017, p.35-76

2017

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Physicochemical and Biopharmaceutical Properties that Affect Drug Absorption of Compounds Absorbed by Passive Diffusion

Oral Bioavailability Assessment, 2017, p.139-171

2017

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In Vitro and In Situ Approaches to Measure Intestinal Permeability and Efflux Transporters

Oral Bioavailability Assessment, 2017, p.331-346

2017

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Drug Pharmacokinetics and Toxicokinetics

Oral Bioavailability Assessment, 2017, p.1-34

2017

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Physicochemical and Biopharmaceutical Factors Affecting Hepatic/Intestinal First-Pass Effect

Oral Bioavailability Assessment, 2017, p.173-201

2017

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Impact of Intestinal Efflux Transporters on Oral Absorption

Oral Bioavailability Assessment, 2017, p.203-267

2017

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In Vivo Preclinical Approaches to Deconvolute The Contribution of First-Pass Effect from Oral Absorption

Oral Bioavailability Assessment, 2017, p.357-376

2017

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Extended Clearance Classification System (ECCS) and its Utility in Predicting Clearance Rate-Determining Step in Drug Discovery

Oral Bioavailability Assessment, 2017, p.309-329

2017

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The Utility of ECCS as a Roadmap to Improve Oral Bioavailability of New Molecular Entities: Industrial Perspective

Oral Bioavailability Assessment, 2017, p.387-430

2017

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Impact of Influx Transporters on Drug Absorption

Oral Bioavailability Assessment, 2017, p.269-307

2017

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Supplemental Images

Oral Bioavailability Assessment, 2017, p.1-8

2017

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In Silico Approaches to Predict Intestinal Permeability

Oral Bioavailability Assessment, 2017, p.347-355

2017

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Drug Routes of Excretion

Oral Bioavailability Assessment, 2017, p.77-138

2017

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Approaches to Assess Hepatic Metabolism and First‐Pass Effect

Oral Bioavailability Assessment, 2017, p.377-385

El‐Kattan, Ayman F

2017

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Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)

Pharmaceutical research, 2015-12, Vol.32 (12), p.3785-3802

2015

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Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

Journal of clinical pharmacology, 2016-07, Vol.56 (S7), p.S99-S109

2016

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Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast

Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters

Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations

The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems

Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine) hexahydro-1H-azepine-2-one as dermal penetration enhancers : side chain length variation and molecular modeling

The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities

Effect of Formulation Variables on the Percutaneous Permeation of Ketoprofen from Gel Formulations

Enhancement of transdermal drug delivery: chemical and physical approaches

Preparation of Amino nictino nitril and its application as corrosion inhibitor for carbon steel

GIT Anatomy and Physiology and Drug Oral Bioavailability: Impact of Species Differences

Physicochemical and Biopharmaceutical Properties that Affect Drug Absorption of Compounds Absorbed by Passive Diffusion

In Vitro and In Situ Approaches to Measure Intestinal Permeability and Efflux Transporters

Drug Pharmacokinetics and Toxicokinetics

Physicochemical and Biopharmaceutical Factors Affecting Hepatic/Intestinal First-Pass Effect

Impact of Intestinal Efflux Transporters on Oral Absorption

In Vivo Preclinical Approaches to Deconvolute The Contribution of First-Pass Effect from Oral Absorption

Extended Clearance Classification System (ECCS) and its Utility in Predicting Clearance Rate-Determining Step in Drug Discovery

The Utility of ECCS as a Roadmap to Improve Oral Bioavailability of New Molecular Entities: Industrial Perspective

Impact of Influx Transporters on Drug Absorption

Supplemental Images

In Silico Approaches to Predict Intestinal Permeability

Drug Routes of Excretion

Approaches to Assess Hepatic Metabolism and First‐Pass Effect

Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)

Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

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