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Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2157411-2157411

2023

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Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors

Archiv der Pharmazie (Weinheim), 2020-08, Vol.353 (8), p.e2000060-n/a

2020

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Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX

Scientific reports, 2022-10, Vol.12 (1), p.16756-16756, Article 16756

2022

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Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2765-2785

2022

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Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFR WT , EGFR T790M , and EGFR L858R )

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2241674-2241674

2023

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Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2489-2511

2022

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New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer

Pharmaceuticals (Basel, Switzerland), 2022-04, Vol.15 (4), p.481

2022

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Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach

European journal of medicinal chemistry, 2022-03, Vol.232, p.114190-114190, Article 114190

2022

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Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors

Bioorganic & medicinal chemistry, 2019-12, Vol.27 (23), p.115126-115126, Article 115126

2019

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Design and synthesis of quinazolin-4-one derivatives as potential anticancer agents and investigation of their interaction with RecQ helicases

Bioorganic chemistry, 2024-03, Vol.144, p.107086-107086, Article 107086

2024

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Rationale design of novel substituted 1,3,5-triazine candidates as dual IDH1(R132H)/ IDH2(R140Q) inhibitors with high selectivity against acute myeloid leukemia: In vitro and in vivo preclinical investigations

Bioorganic chemistry, 2024-08, Vol.149, p.107483, Article 107483

2024

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Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

Bioorganic & medicinal chemistry, 2020-10, Vol.28 (19), p.115687-115687, Article 115687

2020

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Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (2), p.115255-115255, Article 115255

2020

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Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents

Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors

Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX

Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents

Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFR WT , EGFR T790M , and EGFR L858R )

Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies

New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer

Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach

Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors

Design and synthesis of quinazolin-4-one derivatives as potential anticancer agents and investigation of their interaction with RecQ helicases

Rationale design of novel substituted 1,3,5-triazine candidates as dual IDH1(R132H)/ IDH2(R140Q) inhibitors with high selectivity against acute myeloid leukemia: In vitro and in vivo preclinical investigations

Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

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