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MraY-antibiotic complex reveals details of tunicamycin mode of action

Nature chemical biology, 2017-03, Vol.13 (3), p.265-267

2017

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Structural basis for selective inhibition of antibacterial target MraY, a membrane-bound enzyme involved in peptidoglycan synthesis

Drug discovery today, 2018-07, Vol.23 (7), p.1426-1435

2018

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Crystal structure of microsomal prostaglandin E₂ synthase provides insight into diversity in the MAPEG superfamily

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3806-3811

2013

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The rapid "teabag" method for high-end purification of membrane proteins

Scientific reports, 2020-09, Vol.10 (1), p.16167-16167, Article 16167

2020

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Exploring the Active Site of the Antibacterial Target MraY by Modified Tunicamycins

ACS chemical biology, 2020-11, Vol.15 (11), p.2885-2895

2020

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The X-ray Crystal Structures of Wild-type and EQ(I-286) Mutant Cytochrome c Oxidases from Rhodobacter sphaeroides

Journal of molecular biology, 2002-08, Vol.321 (2), p.329-339

2002

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The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site

Nature structural & molecular biology, 2000-10, Vol.7 (10), p.910-917

2000

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Factors determining electron-transfer rates in cytochrome c oxidase: investigation of the oxygen reaction in the R. sphaeroides enzyme

Biochimica et biophysica acta, 1998-10, Vol.1367 (1), p.107-117

1998

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Crystal structure of microsomal prostaglandin E 2 synthase provides insight into diversity in the MAPEG superfamily

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3806-3811

2013

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Selective and Bioavailable HDAC6 2‑(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism

Journal of medicinal chemistry, 2023-10, Vol.66 (20), p.14188-14207

2023

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Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.681-686

2022

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Branched Chain Lipid Metabolism As a Determinant of the N -Acyl Variation of Streptomyces Natural Products

ACS chemical biology, 2021-01, Vol.16 (1), p.116-124

2021

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Oxidation of Ubiquinol by Cytochrome bo3 from Escherichia coli: Kinetics of Electron and Proton Transfer

Biochemistry (Easton), 1997-05, Vol.36 (18), p.5425-5431

1997

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Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.1854-1859

2012

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Crystal structure of microsomal prostaglandin E^sub 2^ synthase provides insight into diversity in the MAPEG superfamily

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3806

2013

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Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1

mAbs, 2015-01, Vol.7 (1), p.152-166

2015

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Affinity maturation of a novel antagonistic human monoclonal antibody with a long V H CDR3 targeting the Class A GPCR formyl-peptide receptor 1

mAbs, 2015-01, Vol.7 (1), p.152-166

2015

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Structure of cytochrome c oxidase: a comparison of the bacterial and mitochondrial enzymes

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2001-01, Vol.1544 (1), p.1-9

2001

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Solutions for the storage and handling of SPINE standard pucks

Journal of synchrotron radiation, 2012-03, Vol.19 (2), p.288-289

2012

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Electron-proton interactions in terminal oxidases

BBA - Bioenergetics, 1998-06, Vol.1365 (1), p.159-169

1998

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Oxidation of Ubiquinol by Cytochrome bo 3 from Escherichia coli: Kinetics of Electron and Proton Transfer

Biochemistry (Easton), 1997-05, Vol.36 (18), p.5425-5431

1997

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Proton-Coupled Structural Changes upon Binding of Carbon Monoxide to Cytochrome cd 1: A Combined Flash Photolysis and X-ray Crystallography Study

Biochemistry (Easton), 2000-09, Vol.39 (36), p.10967-10974

2000

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The X-ray Crystal Structures of Wild-type and EQ(I-286) Mutant Cytochrome c Oxidase from Rhodobacter sphaeroides

Journal of molecular biology, 2002, Vol.321 (2), p.329

2002

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Glutamate 286 in Cytochrome aa3 from Rhodobacter sphaeroides Is Involved in Proton Uptake during the Reaction of the Fully-Reduced Enzyme with Dioxygen

Biochemistry (Easton), 1997-11, Vol.36 (45), p.13824-13829

1997

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MraY-antibiotic complex reveals details of tunicamycin mode of action

Structural basis for selective inhibition of antibacterial target MraY, a membrane-bound enzyme involved in peptidoglycan synthesis

Crystal structure of microsomal prostaglandin E₂ synthase provides insight into diversity in the MAPEG superfamily

The rapid "teabag" method for high-end purification of membrane proteins

Exploring the Active Site of the Antibacterial Target MraY by Modified Tunicamycins

The X-ray Crystal Structures of Wild-type and EQ(I-286) Mutant Cytochrome c Oxidases from Rhodobacter sphaeroides

The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site

Factors determining electron-transfer rates in cytochrome c oxidase: investigation of the oxygen reaction in the R. sphaeroides enzyme

Crystal structure of microsomal prostaglandin E 2 synthase provides insight into diversity in the MAPEG superfamily

Selective and Bioavailable HDAC6 2‑(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism

Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation

Branched Chain Lipid Metabolism As a Determinant of the N -Acyl Variation of Streptomyces Natural Products

Oxidation of Ubiquinol by Cytochrome bo3 from Escherichia coli: Kinetics of Electron and Proton Transfer

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)‑2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma

Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy

Crystal structure of microsomal prostaglandin E^sub 2^ synthase provides insight into diversity in the MAPEG superfamily

Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1

Affinity maturation of a novel antagonistic human monoclonal antibody with a long V H CDR3 targeting the Class A GPCR formyl-peptide receptor 1

Structure of cytochrome c oxidase: a comparison of the bacterial and mitochondrial enzymes

Solutions for the storage and handling of SPINE standard pucks

Electron-proton interactions in terminal oxidases

Oxidation of Ubiquinol by Cytochrome bo 3 from Escherichia coli: Kinetics of Electron and Proton Transfer

Proton-Coupled Structural Changes upon Binding of Carbon Monoxide to Cytochrome cd 1: A Combined Flash Photolysis and X-ray Crystallography Study

The X-ray Crystal Structures of Wild-type and EQ(I-286) Mutant Cytochrome c Oxidase from Rhodobacter sphaeroides

Glutamate 286 in Cytochrome aa3 from Rhodobacter sphaeroides Is Involved in Proton Uptake during the Reaction of the Fully-Reduced Enzyme with Dioxygen

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