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PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice

Journal of interferon & cytokine research, 2014-10, Vol.34 (10), p.759-768

2014

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Recombinant murine growth hormone from E. coli inclusion bodies: Expression, high-pressure solubilization and refolding, and characterization of activity and structure

Biotechnology progress, 2010-05, Vol.26 (3), p.743-749

2010

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Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

Nature (London), 1990-01, Vol.343 (6256), p.341-346

1990

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Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

Nature (London), 1990-01, Vol.343 (6256), p.336-340

1990

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Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b

Journal of interferon & cytokine research, 2013-12, Vol.33 (12), p.769-777

2013

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Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription

Blood, 1997-08, Vol.90 (3), p.1141-1149

1997

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Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity

Experimental hematology, 2006-06, Vol.34 (6), p.697-704

2006

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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A

The Journal of biological chemistry, 2001-04, Vol.276 (14), p.11323-11334

2001

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The Human Interleukin-1 Receptor Antagonist (IL1RN) Gene Is Located in the Chromosome 2q14 Region

Genomics (San Diego, Calif.), 1993, Vol.15 (1), p.173-176

1993

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Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro

The Journal of clinical investigation, 1995-07, Vol.96 (1), p.456-464

1995

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Inhibition of Human Immunodeficiency Virus Type 1 Infectivity by Secretory Leukocyte Protease Inhibitor Occurs Prior to Viral Reverse Transcription

Blood, 1997-08, Vol.90 (3), p.1141-1149

1997

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Regulation of an Endogenous Locus Using a Panel of Designed Zinc Finger Proteins Targeted to Accessible Chromatin Regions

The Journal of biological chemistry, 2001-04, Vol.276 (14), p.11323-11334

2001

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Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction

The Journal of biological chemistry, 1991-06, Vol.266 (16), p.10331-10336

1991

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Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist

The Journal of clinical investigation, 1990-05, Vol.85 (5), p.1694-1697

1990

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Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis

The Journal of clinical investigation, 1994-07, Vol.94 (1), p.449-453

1994

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Interleukin-1 receptor antagonist (IL-1ra) as a probe and as a treatment for IL-1 mediated disease

International journal of immunopharmacology, 1992-04, Vol.14 (3), p.475-480

1992

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Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta

The Journal of biological chemistry, 1995-05, Vol.270 (19), p.11477-11483

1995

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Location of the protease-inhibitory region of secretory leukocyte protease inhibitor

The Journal of biological chemistry, 1990-05, Vol.265 (14), p.7976-7981

1990

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The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1- induced acute inflammation

The American journal of pathology, 1991-03, Vol.138 (3), p.521-524

1991

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Interleukin-1 receptor antagonist binds to the type II interleukin-1 receptor on B cells and neutrophils

The Journal of biological chemistry, 1991-10, Vol.266 (30), p.20311-20315

1991

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Intratracheal administration of endotoxin and cytokines. IV. The soluble tumor necrosis factor receptor type I inhibits acute inflammation

The American journal of pathology, 1993-05, Vol.142 (5), p.1335-1338

1993

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X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution

The Journal of biological chemistry, 1994-04, Vol.269 (17), p.12874-12879

1994

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Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation

The American journal of pathology, 1992-07, Vol.141 (1), p.61-68

1992

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Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation

The Journal of biological chemistry, 1994-03, Vol.269 (9), p.6962-6971

1994

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Human IL-1 receptor antagonist promoter. Cell type-specific activity and identification of regulatory regions

The Journal of immunology (1950), 1992-09, Vol.149 (6), p.2000-2007

1992

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PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice

Recombinant murine growth hormone from E. coli inclusion bodies: Expression, high-pressure solubilization and refolding, and characterization of activity and structure

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b

Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription

Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A

The Human Interleukin-1 Receptor Antagonist (IL1RN) Gene Is Located in the Chromosome 2q14 Region

Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro

Inhibition of Human Immunodeficiency Virus Type 1 Infectivity by Secretory Leukocyte Protease Inhibitor Occurs Prior to Viral Reverse Transcription

Regulation of an Endogenous Locus Using a Panel of Designed Zinc Finger Proteins Targeted to Accessible Chromatin Regions

Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist

Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis

Interleukin-1 receptor antagonist (IL-1ra) as a probe and as a treatment for IL-1 mediated disease

Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta

Location of the protease-inhibitory region of secretory leukocyte protease inhibitor

The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1- induced acute inflammation

Interleukin-1 receptor antagonist binds to the type II interleukin-1 receptor on B cells and neutrophils

Intratracheal administration of endotoxin and cytokines. IV. The soluble tumor necrosis factor receptor type I inhibits acute inflammation

X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution

Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation

Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation

Human IL-1 receptor antagonist promoter. Cell type-specific activity and identification of regulatory regions

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