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Affinity enhancement of antibodies: how low-affinity antibodies produced early in immune responses are followed by high-affinity antibodies later and in memory B-cell responses

Cancer immunology research, 2014-05, Vol.2 (5), p.381-392

Eisen, Herman N

2014

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Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies

Cell, 2015-02, Vol.160 (4), p.785-797

2015

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Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Nature (London), 2010-09, Vol.467 (7315), p.591-595

2010

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Inhibition of Influenza Virus Production in Virus-Infected Mice by RNA Interference

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (23), p.8676-8681

2004

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Evolving concepts of specificity in immune reactions

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (52), p.22373-22380

2010

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Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers

PloS one, 2015-10, Vol.10 (10), p.e0139222

2015

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RNA Interference of Influenza Virus Production by Directly Targeting mRNA for Degradation and Indirectly Inhibiting All Viral RNA Transcription

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2718-2723

2003

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Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines

Nature materials, 2004-03, Vol.3 (3), p.190-196

2004

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Poly-β Amino Ester-Containing Microparticles Enhance the Activity of Nonviral Genetic Vaccines

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (26), p.9534-9539

2004

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Promiscuous binding of extracellular peptides to cell surface class I MHC protein

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4580-4585

2012

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Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virus

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.7-8

2013

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Rapid tolerization of virus-activated tumor-specific CD8⁺ T cells in prostate tumors of TRAMP mice

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.13003-13008

2008

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Different Contributions of Thymopoiesis and Homeostasis-Driven Proliferation to the Reconstitution of Naive and Memory T Cell Compartments

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2989-2994

2002

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Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (52), p.22587-22592

2010

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Competition for Self-Peptide-MHC Complexes and Cytokines between Naïve and Memory CD8+T Cells Expressing the Same or Different T Cell Receptors

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.3041-3046

2004

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Breaking the Affinity Ceiling for Antibodies and T Cell Receptors

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10679-10681

2000

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Heat Shock Fusion Proteins as Vehicles for Antigen Delivery into the Major Histocompatibility Complex Class I Presentation Pathway

Proceedings of the National Academy of Sciences - PNAS, 1997-11, Vol.94 (24), p.13146-13151

1997

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Functional Differences between Memory and Naive CD8 T Cells

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.2976-2981

1999

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Dependence of Lymphopenia-Induced T Cell Proliferation on the Abundance of Peptide/ MHC Epitopes and Strength of Their Interaction with T Cell Receptors

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (4), p.1728-1733

2001

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Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells

The Journal of immunology (1950), 2015-08, Vol.195 (4), p.1591-1598

2015

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Remembrance of Immunology Past: Conversations with Herman Eisen

Annual review of immunology, 2015-01, Vol.33 (1), p.1-28

2015

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Homeostatic T Cell Proliferation in a T Cell-Dendritic Cell Coculture System

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2983-2988

2002

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Soluble Peptide-MHC Monomers Cause Activation of CD8+T Cells through Transfer of the Peptide to T Cell MHC Molecules

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13729-13734

2002

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Stage-Dependent Reactivity of Thymocytes to Self-Peptide-MHC Complexes

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.5038-5043

2007

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The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness

The Journal of immunology (1950), 2009-07, Vol.183 (2), p.1166-1178

2009

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Affinity enhancement of antibodies: how low-affinity antibodies produced early in immune responses are followed by high-affinity antibodies later and in memory B-cell responses

Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Inhibition of Influenza Virus Production in Virus-Infected Mice by RNA Interference

Evolving concepts of specificity in immune reactions

Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers

RNA Interference of Influenza Virus Production by Directly Targeting mRNA for Degradation and Indirectly Inhibiting All Viral RNA Transcription

Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines

Poly-β Amino Ester-Containing Microparticles Enhance the Activity of Nonviral Genetic Vaccines

Promiscuous binding of extracellular peptides to cell surface class I MHC protein

Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virus

Rapid tolerization of virus-activated tumor-specific CD8⁺ T cells in prostate tumors of TRAMP mice

Different Contributions of Thymopoiesis and Homeostasis-Driven Proliferation to the Reconstitution of Naive and Memory T Cell Compartments

Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues

Competition for Self-Peptide-MHC Complexes and Cytokines between Naïve and Memory CD8+T Cells Expressing the Same or Different T Cell Receptors

Breaking the Affinity Ceiling for Antibodies and T Cell Receptors

Heat Shock Fusion Proteins as Vehicles for Antigen Delivery into the Major Histocompatibility Complex Class I Presentation Pathway

Functional Differences between Memory and Naive CD8 T Cells

Dependence of Lymphopenia-Induced T Cell Proliferation on the Abundance of Peptide/ MHC Epitopes and Strength of Their Interaction with T Cell Receptors

Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells

Remembrance of Immunology Past: Conversations with Herman Eisen

Homeostatic T Cell Proliferation in a T Cell-Dendritic Cell Coculture System

Soluble Peptide-MHC Monomers Cause Activation of CD8+T Cells through Transfer of the Peptide to T Cell MHC Molecules

Stage-Dependent Reactivity of Thymocytes to Self-Peptide-MHC Complexes

The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness

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