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Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

Cell metabolism, 2013-12, Vol.18 (6), p.816-830

2013

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HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity

Journal of cellular biochemistry, 2022-05, Vol.123 (5), p.893-905

2022

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The Unique Phenotype of Lipid-Laden Macrophages

International journal of molecular sciences, 2021-04, Vol.22 (8), p.4039

2021

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Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models

FEBS open bio, 2016-09, Vol.6 (9), p.902-913

2016

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Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation

PloS one, 2009-03, Vol.4 (3), p.e4723-e4723

2009

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Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed

Glia, 2013-11, Vol.61 (11), p.1848-1861

2013

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LIM‐only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation

European journal of immunology, 2015-11, Vol.45 (11), p.3098-3106

2015

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Lyso-glycosphingolipids: presence and consequences

Essays in biochemistry, 2020-09, Vol.64 (3), p.565-578

2020

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Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages

International journal of molecular sciences, 2018-12, Vol.20 (1), p.66

2018

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Phenotyping primary human microglia: Tight regulation of LPS responsiveness

Glia, 2012-10, Vol.60 (10), p.1506-1517

2012

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EMR1, the human homolog of F4/80, is an eosinophil-specific receptor

European journal of immunology, 2007-10, Vol.37 (10), p.2797-2802

2007

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The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion

Kidney international, 2015-01, Vol.87 (1), p.85-94

2015

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Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1341-1349

2007

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Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival

PloS one, 2017-07, Vol.12 (7), p.e0182075-e0182075

2017

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Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

PloS one, 2016-01, Vol.11 (1), p.e0147208-e0147208

2016

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Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction

Diabetes (New York, N.Y.), 2014-10, Vol.63 (10), p.3310-3323

2014

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Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity

International immunology, 2005-11, Vol.17 (11), p.1505-1512

2005

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GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2532

2021

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Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

PloS one, 2015-09, Vol.10 (9), p.e0138107-e0138107

2015

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Inflammation aggravates disease severity in Marfan syndrome patients

PloS one, 2012-03, Vol.7 (3), p.e32963-e32963

2012

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Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation

Journal of medicinal chemistry, 2010-01, Vol.53 (2), p.689-698

2010

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Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice

Hepatology (Baltimore, Md.), 2009-11, Vol.50 (5), p.1431-1441

2009

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Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

Journal of lipid research, 2014-01, Vol.55 (1), p.138-145

2014

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The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?

Journal of endocrinology, 2011-02, Vol.208 (2), p.107-117

2011

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Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism

PloS one, 2012-10, Vol.7 (10), p.e38520

2012

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Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity

The Unique Phenotype of Lipid-Laden Macrophages

Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed

LIM‐only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation

Lyso-glycosphingolipids: presence and consequences

Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages

Phenotyping primary human microglia: Tight regulation of LPS responsiveness

EMR1, the human homolog of F4/80, is an eosinophil-specific receptor

The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction

Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

Inflammation aggravates disease severity in Marfan syndrome patients

Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation

Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?

Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism

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