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Recent advances in the structural analysis of adenylation domains in natural product biosynthesis

Current opinion in chemical biology, 2022-12, Vol.71, p.102212-102212, Article 102212

2022

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Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines

Natural product reports, 2018-11, Vol.35 (11), p.1185-129

2018

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Biosynthesis of cyclitols

Natural product reports, 2022-08, Vol.39 (8), p.1622-1642

2022

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Biochemical and crystallographic assessments of the effect of 4,6‐O‐disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity

The FEBS journal, 2023-05, Vol.290 (9), p.2379-2393

2023

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Multisystem Inflammatory Syndrome in Adults after Mild SARS-CoV-2 Infection, Japan

Emerging infectious diseases, 2021-06, Vol.27 (6), p.1740-1742

2021

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Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5′‐Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C35 Bacteriohopanepolyols

Angewandte Chemie International Edition, 2020-01, Vol.59 (1), p.237-241

International ed. in English, 2020

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Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Journal of industrial microbiology & biotechnology, 2019-03, Vol.46 (3-4), p.515-536

2019

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Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR

PLoS biology, 2019-05, Vol.17 (5), p.e3000252-e3000252

2019

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Protein‐Protein Recognition Involved in the Intermodular Transacylation Reaction in Modular Polyketide Synthase in the Biosynthesis of Vicenistatin

Chembiochem : a European journal of chemical biology, 2022-07, Vol.23 (14), p.e202200200-n/a

2022

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Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1802-1807

2016

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Biosynthetic genes for aminoglycoside antibiotics

Journal of antibiotics, 2009-09, Vol.62 (9), p.471-481

2009

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Expression of highly active chondroitin 4-O-sulfotransferase-1 in Escherichia coli by a trigger factor fusion protein expression system

Process biochemistry (1991), 2022-04, Vol.115, p.146-151

2022

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Methylcobalamin-Dependent Radical SAM C‑Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C‑Methylation in Fosfomycin Biosynthesis

Biochemistry (Easton), 2017-07, Vol.56 (28), p.3519-3522

2017

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Structural Characterization of Complex of Adenylation Domain and Carrier Protein by Using Pantetheine Cross-Linking Probe

ACS chemical biology, 2020-07, Vol.15 (7), p.1808-1812

2020

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Genome mining of the sordarin biosynthetic gene cluster from Sordaria araneosa Cain ATCC 36386: characterization of cycloaraneosene synthase and GDP-6-deoxyaltrose transferase

Journal of antibiotics, 2016-07, Vol.69 (7), p.541-548

2016

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Structural Basis of Protein–Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis

Journal of the American Chemical Society, 2018-06, Vol.140 (25), p.7970-7978

2018

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Five-Membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Orthologue in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin

Chembiochem : a European journal of chemical biology, 2016-11, Vol.17 (22), p.2143-2148

2016

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NAD+‐Dependent Dehydrogenase PctP and Pyridoxal 5′‐Phosphate Dependent Aminotransferase PctC Catalyze the First Postglycosylation Modification of the Sugar Intermediate in Pactamycin Biosynthesis

Chembiochem : a European journal of chemical biology, 2018-01, Vol.19 (2), p.126-130

2018

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A Natural Protecting Group Strategy To Carry an Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antibiotics

Journal of the American Chemical Society, 2011-11, Vol.133 (45), p.18134-18137

2011

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Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

Biochemistry (Easton), 2019-12, Vol.58 (51), p.5112-5116

2019

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Substrate specificity of radical S-adenosyl-l-methionine dehydratase AprD4 and its partner reductase AprD3 in the C3'-deoxygenation of aminoglycoside antibiotics

Journal of antibiotics, 2017-04, Vol.70 (4), p.423-428

2017

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Functional Characterization of 3‐Aminobenzoic Acid Adenylation Enzyme PctU and UDP‐N‐Acetyl‐d‐Glucosamine: 3‐Aminobenzoyl‐ACP Glycosyltransferase PctL in Pactamycin Biosynthesis

Chembiochem : a European journal of chemical biology, 2019-10, Vol.20 (19), p.2458-2462

2019

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Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii

ACS chemical biology, 2023-04, Vol.18 (4), p.875-883

2023

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Stepwise Post‐glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis

Chembiochem : a European journal of chemical biology, 2021-05, Vol.22 (9), p.1668-1675

2021

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Generation of incednine derivatives by mutasynthesis

Journal of antibiotics, 2020-11, Vol.73 (11), p.794-797

2020

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Recent advances in the structural analysis of adenylation domains in natural product biosynthesis

Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines

Biosynthesis of cyclitols

Biochemical and crystallographic assessments of the effect of 4,6‐O‐disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity

Multisystem Inflammatory Syndrome in Adults after Mild SARS-CoV-2 Infection, Japan

Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5′‐Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C35 Bacteriohopanepolyols

Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR

Protein‐Protein Recognition Involved in the Intermodular Transacylation Reaction in Modular Polyketide Synthase in the Biosynthesis of Vicenistatin

Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Biosynthetic genes for aminoglycoside antibiotics

Expression of highly active chondroitin 4-O-sulfotransferase-1 in Escherichia coli by a trigger factor fusion protein expression system

Methylcobalamin-Dependent Radical SAM C‑Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C‑Methylation in Fosfomycin Biosynthesis

Structural Characterization of Complex of Adenylation Domain and Carrier Protein by Using Pantetheine Cross-Linking Probe

Genome mining of the sordarin biosynthetic gene cluster from Sordaria araneosa Cain ATCC 36386: characterization of cycloaraneosene synthase and GDP-6-deoxyaltrose transferase

Structural Basis of Protein–Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis

Five-Membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Orthologue in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin

NAD+‐Dependent Dehydrogenase PctP and Pyridoxal 5′‐Phosphate Dependent Aminotransferase PctC Catalyze the First Postglycosylation Modification of the Sugar Intermediate in Pactamycin Biosynthesis

A Natural Protecting Group Strategy To Carry an Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antibiotics

Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

Substrate specificity of radical S-adenosyl-l-methionine dehydratase AprD4 and its partner reductase AprD3 in the C3'-deoxygenation of aminoglycoside antibiotics

Functional Characterization of 3‐Aminobenzoic Acid Adenylation Enzyme PctU and UDP‐N‐Acetyl‐d‐Glucosamine: 3‐Aminobenzoyl‐ACP Glycosyltransferase PctL in Pactamycin Biosynthesis

Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii

Stepwise Post‐glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis

Generation of incednine derivatives by mutasynthesis

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