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DSP-0509, a systemically available TLR7 agonist, exhibits combination effect with immune checkpoint blockade by activating anti-tumor immune effects

Frontiers in immunology, 2023-01, Vol.14, p.1055671-1055671

2023

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Novel Tetranuclear Heterometallic Mn3Ni and Mononuclear Ni Complexes with an ONO Schiff Base Ligand: Synthesis, Crystal Structures, and Magnetic Properties

Magnetochemistry, 2023-11, Vol.9 (11), p.225

2023

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Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Antimicrobial Agents and Chemotherapy, 2013-02, Vol.57 (2), p.697-707

2013

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Pharmacodynamics of SMP-601 (PTZ601) against Vancomycin-Resistant Enterococcus faecium and Methicillin-Resistant Staphylococcus aureus in Neutropenic Murine Thigh Infection Models

Antimicrobial Agents and Chemotherapy, 2009-08, Vol.53 (8), p.3391-3398

2009

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Synthesis and properties of 2′- O,4′- C-methyleneoxymethylene bridged nucleic acid

Bioorganic & medicinal chemistry, 2006-02, Vol.14 (4), p.1029-1038

2006

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Experimental verification of the efficacy of optimized two-step infusion therapy with meropenem using an in vitro pharmacodynamic model and Monte Carlo simulation

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010-02, Vol.16 (1), p.1-9

2010

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In Vitro and In Vivo Antibacterial Activities of SM-216601, a New Broad-Spectrum Parenteral Carbapenem

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4185-4196

2005

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The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Journal of antibiotics, 2007-02, Vol.60 (2), p.129-135

2007

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Preclinical Evaluation of a Novel Orally Bioavailable Menin-MLL Interaction Inhibitor, DSP-5336, for the Treatment of Acute Leukemia Patients with MLL-Rearrangement or NPM1 Mutation

Blood, 2021-11, Vol.138 (Supplement 1), p.3339-3339

2021

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Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients (pts) with Acute Leukemia with and without Mixed-Lineage Leukemia (MLL)-Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Blood, 2021-11, Vol.138 (Supplement 1), p.4431-4431

2021

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Phase 1/2, open-label, dose-escalation, dose-expansion study of menin inhibitor DSP-5336 in adult patients with acute leukemia with and without mixed-lineage leukemia ( MLL )-rearrangement (r) or nucleophosmin 1 ( NPM1 ) mutation (m)

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.TPS7066-TPS7066

2022

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P38-8 Phase 1/2 study of menin inhibitor DSP-5336 in acute leukemia with and without MLL rearrangement or NPM1 mutation

Annals of oncology, 2023-11, Vol.34, p.S1456-S1456

2023

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Poster: AML-391 Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients With Acute Leukemia With and Without Mixed-Lineage Leukemia (MLL)– Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S137

2022

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AML-391 Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients With Acute Leukemia With and Without Mixed-Lineage Leukemia (MLL)– Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S244

2022

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Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients with Acute Leukemia with and without Mixed-Lineage Leukemia (MLL)-Rearrangement (R) or Nucleophosmin 1 (NPM1) Mutation (m)

Blood, 2022-11, Vol.140 (Supplement 1), p.3371-3372

2022

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Novel Tetranuclear Heterometallic Mn[sub.3]Ni and Mononuclear Ni Complexes with an IONO/I Schiff Base Ligand: Synthesis, Crystal Structures, and Magnetic Properties

Magnetochemistry, 2023-11, Vol.9 (11)

2023

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The optical resolution of amino acids by plasma polymerized terpene membranes

Journal of membrane science, 1996-09, Vol.118 (1), p.31-40

1996

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Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

Oncotarget, 2016-03, Vol.7 (13), p.17035-17046

2016

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Abstract 2217: Genomic alteration of bromodomain protein ATAD2 in cancer

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2217-2217

2014

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The Mode of Action of 2-(Thiazol-2-ylthio)-1[beta]-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Journal of antibiotics, 2007-02, Vol.60 (2), p.129

2007

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The mode of action of 2-(thiazol-2-ylthio)-1beta-methylcarbapenems against Pseudomonas aeruginosa: the impact of outer membrane permeability and the contribution of MexAB-OprM efflux system

Journal of antibiotics, 2007-02, Vol.60 (2), p.129-135

2007

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Nanometer scale conductance change in a Langmuir-Blodgett film with the atomic force microscope

Applied physics letters, 1996-01, Vol.68 (2), p.188-190

1996

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Magnetic circularly polarized luminescence of the optical active complex Eu(III)-TFMC

Journal of luminescence, 1988-02, Vol.40, p.889-890

1988

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Bait twig method for soil detection of Rosellinia necatrix, causal agent of white root rot of Japanese pear and apple, at an early stage of tree infection

Journal of general plant pathology : JGPP, 2009-10, Vol.75 (5), p.325-330

2009

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Application and Progress in the Scanning Probe Microscopy. High Density Information Storage Using Langmuir-Blodgett Film and Atomic Force Microscopy

Hyōmen kagaku, 1997, Vol.18 (4), p.213-218

1997

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DSP-0509, a systemically available TLR7 agonist, exhibits combination effect with immune checkpoint blockade by activating anti-tumor immune effects

Novel Tetranuclear Heterometallic Mn3Ni and Mononuclear Ni Complexes with an ONO Schiff Base Ligand: Synthesis, Crystal Structures, and Magnetic Properties

Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Pharmacodynamics of SMP-601 (PTZ601) against Vancomycin-Resistant Enterococcus faecium and Methicillin-Resistant Staphylococcus aureus in Neutropenic Murine Thigh Infection Models

Synthesis and properties of 2′- O,4′- C-methyleneoxymethylene bridged nucleic acid

Experimental verification of the efficacy of optimized two-step infusion therapy with meropenem using an in vitro pharmacodynamic model and Monte Carlo simulation

In Vitro and In Vivo Antibacterial Activities of SM-216601, a New Broad-Spectrum Parenteral Carbapenem

The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Preclinical Evaluation of a Novel Orally Bioavailable Menin-MLL Interaction Inhibitor, DSP-5336, for the Treatment of Acute Leukemia Patients with MLL-Rearrangement or NPM1 Mutation

Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients (pts) with Acute Leukemia with and without Mixed-Lineage Leukemia (MLL)-Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Phase 1/2, open-label, dose-escalation, dose-expansion study of menin inhibitor DSP-5336 in adult patients with acute leukemia with and without mixed-lineage leukemia ( MLL )-rearrangement (r) or nucleophosmin 1 ( NPM1 ) mutation (m)

P38-8 Phase 1/2 study of menin inhibitor DSP-5336 in acute leukemia with and without MLL rearrangement or NPM1 mutation

Poster: AML-391 Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients With Acute Leukemia With and Without Mixed-Lineage Leukemia (MLL)– Rearrangement or Nucleophosmin 1 (NPM1) Mutation

AML-391 Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients With Acute Leukemia With and Without Mixed-Lineage Leukemia (MLL)– Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Phase 1/2, Open-Label, Dose Escalation, Dose Expansion Study of Menin Inhibitor DSP-5336 in Adult Patients with Acute Leukemia with and without Mixed-Lineage Leukemia (MLL)-Rearrangement (R) or Nucleophosmin 1 (NPM1) Mutation (m)

Novel Tetranuclear Heterometallic Mn[sub.3]Ni and Mononuclear Ni Complexes with an IONO/I Schiff Base Ligand: Synthesis, Crystal Structures, and Magnetic Properties

The optical resolution of amino acids by plasma polymerized terpene membranes

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

Abstract 2217: Genomic alteration of bromodomain protein ATAD2 in cancer

The Mode of Action of 2-(Thiazol-2-ylthio)-1[beta]-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

The mode of action of 2-(thiazol-2-ylthio)-1beta-methylcarbapenems against Pseudomonas aeruginosa: the impact of outer membrane permeability and the contribution of MexAB-OprM efflux system

Nanometer scale conductance change in a Langmuir-Blodgett film with the atomic force microscope

Magnetic circularly polarized luminescence of the optical active complex Eu(III)-TFMC

Bait twig method for soil detection of Rosellinia necatrix, causal agent of white root rot of Japanese pear and apple, at an early stage of tree infection

Application and Progress in the Scanning Probe Microscopy. High Density Information Storage Using Langmuir-Blodgett Film and Atomic Force Microscopy

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