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Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase

The FEBS journal, 2008-07, Vol.275 (13), p.3278-3289

2008

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C‐terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase

The FEBS journal, 2015-08, Vol.282 (16), p.3075-3090

2015

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The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants

The Journal of biological chemistry, 2020-10, Vol.295 (44), p.14793-14804

2020

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Protein Conformational Gating of Enzymatic Activity in Xanthine Oxidoreductase

Journal of the American Chemical Society, 2012-01, Vol.134 (2), p.999-1009

2012

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The Crystal Structure of Xanthine Oxidoreductase during Catalysis: Implications for Reaction Mechanism and Enzyme Inhibition

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (21), p.7931-7936

2004

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Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Structure (London), 2017-02, Vol.25 (2), p.384-392

2017

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Crystal Structures of Bovine Milk Xanthine Dehydrogenase and Xanthine Oxidase: Structure-Based Mechanism of Conversion

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10723-10728

2000

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Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate

Journal of the American Chemical Society, 2010-12, Vol.132 (48), p.17080-17083

2010

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Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion

The Journal of pharmacology and experimental therapeutics, 2004-11, Vol.311 (2), p.519

2004

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Unique Amino Acids Cluster for Switching from the Dehydrogenase to Oxidase Form of Xanthine Oxidoreductase

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8170-8175

2003

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Structural evidence for visual arrestin priming via complexation of phosphoinositols

Structure (London), 2022-02, Vol.30 (2), p.263-277.e5

2022

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Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography

Acta crystallographica. Section D, Structural biology, 2016-08, Vol.72 (8), p.944-955

2016

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An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition

The Journal of biological chemistry, 2003-01, Vol.278 (3), p.1848-1855

2003

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Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity

Journal of medicinal chemistry, 2016-01, Vol.59 (2), p.624-646

2016

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A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin

Journal of molecular biology, 2018-10, Vol.430 (21), p.4102-4118

2018

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Mechanism of Inhibition of Xanthine Oxidoreductase by Allopurinol: Crystal Structure of Reduced Bovine Milk Xanthine Oxidoreductase Bound with Oxipurinol

Nucleosides, nucleotides & nucleic acids, 2008-06, Vol.27 (6-7), p.888-893

2008

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Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24888-24894

2005

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ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores

Communications biology, 2019-11, Vol.2 (1), p.410-410, Article 410

2019

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Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of ClpP Protease

Chemistry & biology, 2011-09, Vol.18 (9), p.1167-1178

2011

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Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Biophysical journal, 2017-02, Vol.112 (3), p.356a-357a

2017

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Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Structure (London), 2017-02, Vol.25 (2)

2017

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Advances in in situ X-ray Crystallography of Membrane Proteins

Biophysical journal, 2016-02, Vol.110 (3), p.39a-39a

2016

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Differences in Binding Modes of Enantiomers of 1-Acetamido Boronic Acid Based Protease Inhibitors: Crystal Structures of γ-Chymotrypsin and Subtilisin Carlsberg Complexes

Biochemistry (Easton), 1998-01, Vol.37 (2), p.451-462

1998

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Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24888-24894

2005

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An Extremely Potent Inhibitor of Xanthine Oxidoreductase

The Journal of biological chemistry, 2003-01, Vol.278 (3), p.1848-1855

2003

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Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase

C‐terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase

The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants

Protein Conformational Gating of Enzymatic Activity in Xanthine Oxidoreductase

The Crystal Structure of Xanthine Oxidoreductase during Catalysis: Implications for Reaction Mechanism and Enzyme Inhibition

Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Crystal Structures of Bovine Milk Xanthine Dehydrogenase and Xanthine Oxidase: Structure-Based Mechanism of Conversion

Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate

Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion

Unique Amino Acids Cluster for Switching from the Dehydrogenase to Oxidase Form of Xanthine Oxidoreductase

Structural evidence for visual arrestin priming via complexation of phosphoinositols

Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography

An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition

Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity

A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin

Mechanism of Inhibition of Xanthine Oxidoreductase by Allopurinol: Crystal Structure of Reduced Bovine Milk Xanthine Oxidoreductase Bound with Oxipurinol

Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant

ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores

Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of ClpP Protease

Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs

Advances in in situ X-ray Crystallography of Membrane Proteins

Differences in Binding Modes of Enantiomers of 1-Acetamido Boronic Acid Based Protease Inhibitors: Crystal Structures of γ-Chymotrypsin and Subtilisin Carlsberg Complexes

Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase

An Extremely Potent Inhibitor of Xanthine Oxidoreductase

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