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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

Nature communications, 2015-02, Vol.6 (1), p.6221-6221, Article 6221

2015

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Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells

PloS one, 2022-04, Vol.17 (4), p.e0266218

2022

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Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys

Nature communications, 2024-05, Vol.15 (1), p.4247-4247, Article 4247

2024

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Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis

The Journal of immunology (1950), 2011-06, Vol.186 (12), p.6990-6998

2011

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Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

Science (American Association for the Advancement of Science), 2004-04, Vol.304 (5670), p.600-602

2004

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Non-Modulator Therapies: Developing a Therapy for Every Cystic Fibrosis Patient

Clinics in chest medicine, 2022-12, Vol.43 (4), p.717-725

Egan, Marie E

2022

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Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

Scientific reports, 2017-09, Vol.7 (1), p.10882-11, Article 10882

2017

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Emerging technologies for cystic fibrosis transmembrane conductance regulator restoration in all people with CF

Pediatric pulmonology, 2021-02, Vol.56 (S1), p.S32-S39

Egan, Marie E.

2021

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Cystic fibrosis transmembrane conductance receptor modulator therapy in cystic fibrosis, an update

Current opinion in pediatrics, 2020-06, Vol.32 (3), p.384-388

Egan, Marie E

2020

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Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis

Experimental and Molecular Medicine, 2022, 54(0), , pp.1-14

2022

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Genetics of Cystic Fibrosis: Clinical Implications

Clinics in chest medicine, 2016-03, Vol.37 (1), p.9-16

Egan, Marie E

2016

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Myosin Ia is Required for CFTR Brush Border Membrane Trafficking and Ion Transport in the Mouse Small Intestine

Traffic (Copenhagen, Denmark), 2012-08, Vol.13 (8), p.1072-1082

2012

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Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report

Annals of the American Thoracic Society, 2021-07, Vol.18 (7), p.1087-1097

2021

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Effects of Lumacaftor/Ivacaftor in a Pediatric Cohort Homozygous for F508del-CFTR

American journal of respiratory and critical care medicine, 2017-04, Vol.195 (7), p.849-850

Egan, Marie E

2017

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CFTR Is a Conductance Regulator as well as a Chloride Channel

Physiological reviews, 1999-01, Vol.79 (1), p.145-S166

1999

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Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis

American journal of respiratory and critical care medicine, 2020-11, Vol.202 (10), p.1419-1429

2020

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Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

Nature communications, 2015-04, Vol.6 (1), p.6952-6952, Article 6952

2015

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Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (13), p.6082-6087

2010

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Assessment of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity in CFTR-Null Mice after Bone Marrow Transplantation

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (8), p.2965-2970

2006

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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

Cell reports (Cambridge), 2022-12, Vol.41 (11), p.111797-111797, Article 111797

2022

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Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

Journal of controlled release, 2012-11, Vol.164 (1), p.41-48

2012

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Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator-/- Mice

American journal of respiratory cell and molecular biology, 2009-03, Vol.40 (3), p.295-304

2009

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Nanoparticles for delivery of agents to fetal lungs

Acta biomaterialia, 2021-03, Vol.123, p.346-353

2021

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Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation

Journal of cystic fibrosis, 2024-08

2024

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Association between serum 25-hydroxyvitamin D level and pulmonary exacerbations in cystic fibrosis

Pediatric pulmonology, 2015-05, Vol.50 (5), p.441-446

2015

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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells

Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys

Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis

Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

Non-Modulator Therapies: Developing a Therapy for Every Cystic Fibrosis Patient

Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

Emerging technologies for cystic fibrosis transmembrane conductance regulator restoration in all people with CF

Cystic fibrosis transmembrane conductance receptor modulator therapy in cystic fibrosis, an update

Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis

Genetics of Cystic Fibrosis: Clinical Implications

Myosin Ia is Required for CFTR Brush Border Membrane Trafficking and Ion Transport in the Mouse Small Intestine

Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report

Effects of Lumacaftor/Ivacaftor in a Pediatric Cohort Homozygous for F508del-CFTR

CFTR Is a Conductance Regulator as well as a Chloride Channel

Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis

Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct

Assessment of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity in CFTR-Null Mice after Bone Marrow Transplantation

Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator-/- Mice

Nanoparticles for delivery of agents to fetal lungs

Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation

Association between serum 25-hydroxyvitamin D level and pulmonary exacerbations in cystic fibrosis

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