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Epigenetic Memory: Lessons From iPS Cells Derived From Human β Cells

Frontiers in endocrinology (Lausanne), 2021-01, Vol.11, p.614234-614234

Efrat, Shimon

2021

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Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

Cell stem cell, 2011-07, Vol.9 (1), p.17-23

2011

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TGFβ Pathway Inhibition Redifferentiates Human Pancreatic Islet β Cells Expanded In Vitro

PloS one, 2015-09, Vol.10 (9), p.e0139168-e0139168

2015

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Beta‐Cell Dedifferentiation in Type 2 Diabetes: Concise Review

Stem cells (Dayton, Ohio), 2019-10, Vol.37 (10), p.1267-1272

Efrat, Shimon

2019

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Redifferentiation of adult human β cells expanded in vitro by inhibition of the WNT pathway

PloS one, 2014-11, Vol.9 (11), p.e112914-e112914

2014

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Generation of Insulin‐Producing Cells from Human Bone Marrow Mesenchymal Stem Cells by Genetic Manipulation

Stem cells (Dayton, Ohio), 2007-11, Vol.25 (11), p.2837-2844

2007

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In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

Diabetes (New York, N.Y.), 2008-06, Vol.57 (6), p.1575-1583

2008

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MiR-375 promotes redifferentiation of adult human β cells expanded in vitro

PloS one, 2015-04, Vol.10 (4), p.e0122108-e0122108

2015

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Differentiation of Human Liver-Derived, Insulin-Producing Cells Toward the β-Cell Phenotype

Diabetes (New York, N.Y.), 2005-09, Vol.54 (9), p.2568-2575

2005

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Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells

PloS one, 2009-07, Vol.4 (7), p.e6417-e6417

2009

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Lineage Tracing Evidence for In Vitro Dedifferentiation but Rare Proliferation of Mouse Pancreatic β-Cells

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1299-1304

2007

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Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro

PloS one, 2011-09, Vol.6 (9), p.e25566

2011

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Expansion and redifferentiation of adult human pancreatic islet cells

Biochemical and biophysical research communications, 2006-03, Vol.341 (2), p.291-298

2006

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Reversal of Hyperglycemia in Mice by Using Human Expandable Insulin-Producing Cells Differentiated from Fetal Liver Progenitor Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (12), p.7253-7258

2003

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HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

Diabetes (New York, N.Y.), 2008-09, Vol.57 (9), p.2413-2420

2008

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Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells

Stem cell reports, 2017-11, Vol.9 (5), p.1395-1405

2017

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Beta-cell replacement for insulin-dependent diabetes mellitus

Advanced drug delivery reviews, 2008-01, Vol.60 (2), p.114-123

Efrat, Shimon

2008

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Recent progress in generation of human surrogate β cells

Current opinion in endocrinology, diabetes, and obesity, 2013-08, Vol.20 (4), p.259-264

Efrat, Shimon

2013

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Redifferentiation of expanded human islet β cells by inhibition of ARX

Scientific reports, 2016-02, Vol.6 (1), p.20698-20698, Article 20698

2016

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TGF[beta] Pathway Inhibition Redifferentiates Human Pancreatic Islet [beta] Cells Expanded In Vitro.(Transforming growth factor [beta])

PloS one, 2015-09, Vol.10 (9)

2015

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The NOTCH Pathway in β-Cell Growth and Differentiation

Vitamins and Hormones, 2014, Vol.95, p.391-405

2014

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Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in β cells prevent autoimmune diabetes

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (46), p.19450-19454

2009

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Inhibition of Islet Amyloid Polypeptide Fibril Formation: A Potential Role for Heteroaromatic Interactions

Biochemistry (Easton), 2004-11, Vol.43 (45), p.14454-14462

2004

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Correction of Hyperglycemia in Diabetic Mice Transplanted with Reversibly Immortalized Pancreatic β Cells Controlled by the tet-on Regulatory System

Cell transplantation, 2001-01, Vol.10 (7), p.645-650

2001

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Beta-cell replacement for insulin-dependent diabetes mellitus: Emerging trends in cell-based therapies

Advanced drug delivery reviews, 2008, Vol.60 (2), p.114-123

EFRAT, Shimon

2008

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Epigenetic Memory: Lessons From iPS Cells Derived From Human β Cells

Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

TGFβ Pathway Inhibition Redifferentiates Human Pancreatic Islet β Cells Expanded In Vitro

Beta‐Cell Dedifferentiation in Type 2 Diabetes: Concise Review

Redifferentiation of adult human β cells expanded in vitro by inhibition of the WNT pathway

Generation of Insulin‐Producing Cells from Human Bone Marrow Mesenchymal Stem Cells by Genetic Manipulation

In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

MiR-375 promotes redifferentiation of adult human β cells expanded in vitro

Differentiation of Human Liver-Derived, Insulin-Producing Cells Toward the β-Cell Phenotype

Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells

Lineage Tracing Evidence for In Vitro Dedifferentiation but Rare Proliferation of Mouse Pancreatic β-Cells

Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro

Expansion and redifferentiation of adult human pancreatic islet cells

Reversal of Hyperglycemia in Mice by Using Human Expandable Insulin-Producing Cells Differentiated from Fetal Liver Progenitor Cells

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells

Beta-cell replacement for insulin-dependent diabetes mellitus

Recent progress in generation of human surrogate β cells

Redifferentiation of expanded human islet β cells by inhibition of ARX

TGF[beta] Pathway Inhibition Redifferentiates Human Pancreatic Islet [beta] Cells Expanded In Vitro.(Transforming growth factor [beta])

The NOTCH Pathway in β-Cell Growth and Differentiation

Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in β cells prevent autoimmune diabetes

Inhibition of Islet Amyloid Polypeptide Fibril Formation: A Potential Role for Heteroaromatic Interactions

Correction of Hyperglycemia in Diabetic Mice Transplanted with Reversibly Immortalized Pancreatic β Cells Controlled by the tet-on Regulatory System

Beta-cell replacement for insulin-dependent diabetes mellitus: Emerging trends in cell-based therapies

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