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Predicting Plasma Concentrations of Bisphenol A in Children Younger than 2 Years of Age after Typical Feeding Schedules, Using a Physiologically Based Toxicokinetic Model

Environmental health perspectives, 2009-04, Vol.117 (4), p.645-652

2009

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Development and evaluation of a generic physiologically based pharmacokinetic model for children

Clinical pharmacokinetics, 2006-01, Vol.45 (10), p.1013-1034

2006

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Improving Pediatric Protein Binding Estimates: An Evaluation of α1-Acid Glycoprotein Maturation in Healthy and Infected Subjects

Clinical pharmacokinetics, 2018-05, Vol.57 (5), p.577-589

2018

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Cost‐utility analysis of emicizumab for the treatment of severe hemophilia A patients in Canada

Haemophilia : the official journal of the World Federation of Hemophilia, 2023-03, Vol.29 (2), p.488-497

2023

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The use of pharmacokinetics in dose individualization of factor VIII in the treatment of hemophilia A

Expert opinion on drug metabolism & toxicology, 2016-11, Vol.12 (11), p.1313-1321

2016

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Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

CPT: pharmacometrics and systems pharmacology, 2019-11, Vol.8 (11), p.835-844

2019

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Assessment of Vehicle Volatility and Deposition Layer Thickness in Skin Penetration Models

Pharmaceutics, 2021-05, Vol.13 (6), p.807

2021

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Characterizing Pharmacokinetics in Children With Obesity-Physiological, Drug, Patient, and Methodological Considerations

Frontiers in pharmacology, 2022-03, Vol.13, p.818726

2022

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Development of a Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Study Protocol

JMIR research protocols, 2016-12, Vol.5 (4), p.e239-e239

2016

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Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children

Pharmaceutics, 2022-01, Vol.14 (1), p.172

2022

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A mechanistic approach for the scaling of clearance in children

Clinical pharmacokinetics, 2006-01, Vol.45 (7), p.683-704

2006

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Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation

Pharmaceutics, 2019-04, Vol.11 (4), p.179

2019

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Addressing maternal medication use during breastfeeding using clinical resources and a novel physiologically based pharmacokinetic model-derived metric: A qualitative study

Frontiers in pediatrics, 2023-04, Vol.11, p.1147566-1147566

2023

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Verifying in vitro‐determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically‐based pharmacokinetic modeling

CPT: pharmacometrics and systems pharmacology, 2023-03, Vol.12 (3), p.320-332

2023

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A personalized limited sampling approach to better estimate terminal half‐life of FVIII concentrates

Journal of thrombosis and haemostasis, 2022-09, Vol.20 (9), p.2012-2021

2022

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Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling

CPT: pharmacometrics and systems pharmacology, 2024-04, Vol.13 (4), p.576-588

2024

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Modeling of Body Weight Metrics for Effective and Cost-Efficient Conventional Factor VIII Dosing in Hemophilia A Prophylaxis

Pharmaceutics, 2017-10, Vol.9 (4), p.47

2017

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Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds

Journal of Toxicology and Environmental Health, Part A, 2019-07, Vol.82 (14), p.789-814

2019

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Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility

Pharmaceutical research, 2016, Vol.33 (1), p.52-71

2016

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Anakinra Removal by Continuous Renal Replacement Therapy: An Ex Vivo Analysis

Critical care explorations, 2023-12, Vol.5 (12), p.e1010-e1010

2023

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Predicting Individual Changes in Terminal Half‐Life After Switching to Extended Half‐Life Concentrates in Patients With Severe Hemophilia

HemaSphere, 2022-04, Vol.6 (4), p.e694-n/a

2022

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Physiology-Based Simulations of a Pathological Condition: Prediction of Pharmacokinetics in Patients with Liver Cirrhosis

Clinical pharmacokinetics, 2008-01, Vol.47 (11), p.743-752

2008

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Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi‐country severe WAPPS‐Hemo haemophilia patients

Haemophilia : the official journal of the World Federation of Hemophilia, 2024-07, Vol.30 (4), p.925-932

2024

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Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study

Haemophilia : the official journal of the World Federation of Hemophilia, 2021-05, Vol.27 (3), p.358-365

2021

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Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.1080-1089

2016

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Predicting Plasma Concentrations of Bisphenol A in Children Younger than 2 Years of Age after Typical Feeding Schedules, Using a Physiologically Based Toxicokinetic Model

Development and evaluation of a generic physiologically based pharmacokinetic model for children

Improving Pediatric Protein Binding Estimates: An Evaluation of α1-Acid Glycoprotein Maturation in Healthy and Infected Subjects

Cost‐utility analysis of emicizumab for the treatment of severe hemophilia A patients in Canada

The use of pharmacokinetics in dose individualization of factor VIII in the treatment of hemophilia A

Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

Assessment of Vehicle Volatility and Deposition Layer Thickness in Skin Penetration Models

Characterizing Pharmacokinetics in Children With Obesity-Physiological, Drug, Patient, and Methodological Considerations

Development of a Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Study Protocol

Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children

A mechanistic approach for the scaling of clearance in children

Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation

Addressing maternal medication use during breastfeeding using clinical resources and a novel physiologically based pharmacokinetic model-derived metric: A qualitative study

Verifying in vitro‐determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically‐based pharmacokinetic modeling

A personalized limited sampling approach to better estimate terminal half‐life of FVIII concentrates

Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling

Modeling of Body Weight Metrics for Effective and Cost-Efficient Conventional Factor VIII Dosing in Hemophilia A Prophylaxis

Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds

Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility

Anakinra Removal by Continuous Renal Replacement Therapy: An Ex Vivo Analysis

Predicting Individual Changes in Terminal Half‐Life After Switching to Extended Half‐Life Concentrates in Patients With Severe Hemophilia

Physiology-Based Simulations of a Pathological Condition: Prediction of Pharmacokinetics in Patients with Liver Cirrhosis

Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi‐country severe WAPPS‐Hemo haemophilia patients

Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study

Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?

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