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Influence of multiplicity of infection and protein stability on retroviral vector-mediated gene expression in hematopoietic cells

Gene therapy, 2001-03, Vol.8 (6), p.477-486

2001

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Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice

Blood, 2000-02, Vol.95 (4), p.1237-1248

2000

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Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells

Journal of Virology, 1995-12, Vol.69 (12), p.7541-7547

1995

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Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

Gene therapy, 2001-02, Vol.8 (3), p.239-246

2001

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FMEV vectors : both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells

Gene therapy, 1998-11, Vol.5 (11), p.1575-1579

1998

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Murine Leukemia Induced by Retroviral Gene Marking

Science (American Association for the Advancement of Science), 2002-04, Vol.296 (5567), p.497-497

2002

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MDR1 Gene Expression in NOD/SCID Repopulating Cells after Retroviral Gene Transfer under Clinically Relevant Conditions

Molecular therapy, 2000-12, Vol.2 (6), p.609-618

2000

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Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1)

Bone marrow transplantation (Basingstoke), 2000-05, Vol.25 Suppl 2 (S2), p.S114-S117

2000

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Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements

Gene therapy, 1999-10, Vol.6 (10), p.1788-1792

1999

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Bicistronic retroviral vectors for combining myeloprotection with cell-surface marking

Gene therapy, 1999-07, Vol.6 (7), p.1222-1230

1999

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Genetic modification of haematopoietic cells for combined resistance to podophyllotoxins, other agents covered by MDR1-mediated efflux activity and nitrosoureas

Bone marrow transplantation (Basingstoke), 2000-05, Vol.25 Suppl 2 (S2), p.S71-S74

2000

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High-Dose Multidrug Resistance in Primary Human Hematopoietic Progenitor Cells Transduced With Optimized Retroviral Vectors

Blood, 1996-11, Vol.88 (9), p.3407-3415

1996

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The effects of dose, route of administration, drug scheduling and MDR-1 gene transfer on the genotoxicity of etoposide in bone marrow

Leukemia, 2000-10, Vol.14 (10), p.1796-1802

2000

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Retroviral transduction of T lymphocytes for suicide gene therapy in allogeneic stem cell transplantation

Bone marrow transplantation (Basingstoke), 2000-05, Vol.25 Suppl 2 (S2), p.S96-S98

2000

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Optimization of retroviral vector generation for clinical application

The journal of gene medicine, 2001-09, Vol.3 (5), p.427-436

2001

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Gene transfer to augment the therapeutic index of anticancer chemotherapy

Gene therapy, 1996-01, Vol.3 (1), p.1

1996

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Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells

Bone marrow transplantation (Basingstoke), 2000-05, Vol.25 Suppl 2 (S2), p.S118-S124

2000

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Cis-Active Elements of Friend Spleen Focus-Forming Virus: From Disease Induction to Disease Prevention

Acta haematologica, 1998-01, Vol.99 (3), p.156-164

1998

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Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

Human gene therapy, 2002-01, Vol.13 (2), p.233-242

2002

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Lack of interaction between ramipril and simvastatin

European journal of clinical pharmacology, 1994-11, Vol.47 (4), p.373-375

1994

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Selective immunoaffinity-based enrichment of CD34+ cells transduced with retroviral vectors containing an intracytoplasmatically truncated version of the human low-affinity nerve growth factor receptor (deltaLNGFR) gene

Human gene therapy, 1997-10, Vol.8 (15), p.1815-1824

1997

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Safety, tolerance and pharmacokinetics of cefpirome administered intramuscularly to healthy subjects

Journal of antimicrobial chemotherapy, 1992-04, Vol.29 (suppl-A), p.63-70

1992

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Safety, tolerance and pharmacokinetics of 2.0 g cefpirome (HR 810) after single and multiple dosing

Chemotherapy (Basel), 1988, Vol.34 (5), p.367

1988

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Pharmacokinetics and metabolism of HOE 077: Preclinical studies

Journal of hepatology, 1991, Vol.13, p.S48-S62

1991

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Synthesis of probable and improbable precursors for porphyrin biosynthesis

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 1976-02, Vol.273 (924), p.181

1976

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Influence of multiplicity of infection and protein stability on retroviral vector-mediated gene expression in hematopoietic cells

Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice

Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells

Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

FMEV vectors : both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells

Murine Leukemia Induced by Retroviral Gene Marking

MDR1 Gene Expression in NOD/SCID Repopulating Cells after Retroviral Gene Transfer under Clinically Relevant Conditions

Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1)

Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements

Bicistronic retroviral vectors for combining myeloprotection with cell-surface marking

Genetic modification of haematopoietic cells for combined resistance to podophyllotoxins, other agents covered by MDR1-mediated efflux activity and nitrosoureas

High-Dose Multidrug Resistance in Primary Human Hematopoietic Progenitor Cells Transduced With Optimized Retroviral Vectors

The effects of dose, route of administration, drug scheduling and MDR-1 gene transfer on the genotoxicity of etoposide in bone marrow

Retroviral transduction of T lymphocytes for suicide gene therapy in allogeneic stem cell transplantation

Optimization of retroviral vector generation for clinical application

Gene transfer to augment the therapeutic index of anticancer chemotherapy

Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells

Cis-Active Elements of Friend Spleen Focus-Forming Virus: From Disease Induction to Disease Prevention

Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

Lack of interaction between ramipril and simvastatin

Selective immunoaffinity-based enrichment of CD34+ cells transduced with retroviral vectors containing an intracytoplasmatically truncated version of the human low-affinity nerve growth factor receptor (deltaLNGFR) gene

Safety, tolerance and pharmacokinetics of cefpirome administered intramuscularly to healthy subjects

Safety, tolerance and pharmacokinetics of 2.0 g cefpirome (HR 810) after single and multiple dosing

Pharmacokinetics and metabolism of HOE 077: Preclinical studies

Synthesis of probable and improbable precursors for porphyrin biosynthesis

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