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Structural basis of transcription-translation coupling

Science (American Association for the Advancement of Science), 2020-09, Vol.369 (6509), p.1359-1365

2020

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Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3)

Molecular cell, 2018-04, Vol.70 (1), p.60-71.e15

2018

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Structural basis of Rho-dependent transcription termination

Nature (London), 2023-02, Vol.614 (7947), p.367-374

2023

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Structural Basis of Transcription Initiation

Science (American Association for the Advancement of Science), 2012-11, Vol.338 (6110), p.1076-1080

2012

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The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation

Molecular cell, 2011-07, Vol.43 (2), p.263-274

2011

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Opening and Closing of the Bacterial RNA Polymerase Clamp

Science (American Association for the Advancement of Science), 2012-08, Vol.337 (6094), p.591-595

2012

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New target for inhibition of bacterial RNA polymerase: ‘switch region’

Current opinion in microbiology, 2011-10, Vol.14 (5), p.532-543

2011

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Interactions between RNA polymerase and the "core recognition element" counteract pausing

Science (American Association for the Advancement of Science), 2014-06, Vol.344 (6189), p.1285-1289

2014

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Massively Systematic Transcript End Readout, “MASTER”: Transcription Start Site Selection, Transcriptional Slippage, and Transcript Yields

Molecular cell, 2015-12, Vol.60 (6), p.953-965

2015

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Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching

Science (American Association for the Advancement of Science), 2006-11, Vol.314 (5802), p.1139-1143

2006

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Structural basis of ECF-σ-factor-dependent transcription initiation

Nature communications, 2019-02, Vol.10 (1), p.710-710, Article 710

2019

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Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates

Nature communications, 2018-07, Vol.9 (1), p.2930-10, Article 2930

2018

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Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism

Science (American Association for the Advancement of Science), 2006-11, Vol.314 (5802), p.1144-1147

2006

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Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.6927-6932

2009

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Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase

Journal of industrial microbiology & biotechnology, 2019-03, Vol.46 (3-4), p.335-343

2019

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XACT-Seq Comprehensively Defines the Promoter-Position and Promoter-Sequence Determinants for Initial-Transcription Pausing

Molecular cell, 2020-09, Vol.79 (5), p.797-811.e8

2020

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Transcription inhibition by the depsipeptide antibiotic salinamide A

eLife, 2014-04, Vol.3, p.e02451

2014

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Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles

Structure (London), 2015-08, Vol.23 (8), p.1470-1481

2015

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GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides

eLife, 2014-04, Vol.3, p.e02450

2014

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Accurate FRET Measurements within Single Diffusing Biomolecules Using Alternating-Laser Excitation

Biophysical journal, 2005-04, Vol.88 (4), p.2939-2953

2005

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Transcription activation by catabolite activator protein (CAP)

Journal of molecular biology, 1999-10, Vol.293 (2), p.199-213

1999

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Highly efficient 5' capping of mitochondrial RNA with NAD + and NADH by yeast and human mitochondrial RNA polymerase

eLife, 2018-12, Vol.7

2018

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Systematic Structure-Activity Analysis of Microcin J25

The Journal of biological chemistry, 2008-09, Vol.283 (37), p.25589-25595

2008

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The RNA Polymerase “Switch Region” Is a Target for Inhibitors

Cell, 2008-10, Vol.135 (2), p.295-307

2008

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Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2012-12, Vol.56 (12), p.6250-6255

2012

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Structural basis of transcription-translation coupling

Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3)

Structural basis of Rho-dependent transcription termination

Structural Basis of Transcription Initiation

The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation

Opening and Closing of the Bacterial RNA Polymerase Clamp

New target for inhibition of bacterial RNA polymerase: ‘switch region’

Interactions between RNA polymerase and the "core recognition element" counteract pausing

Massively Systematic Transcript End Readout, “MASTER”: Transcription Start Site Selection, Transcriptional Slippage, and Transcript Yields

Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching

Structural basis of ECF-σ-factor-dependent transcription initiation

Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates

Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase

XACT-Seq Comprehensively Defines the Promoter-Position and Promoter-Sequence Determinants for Initial-Transcription Pausing

Transcription inhibition by the depsipeptide antibiotic salinamide A

Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles

GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides

Accurate FRET Measurements within Single Diffusing Biomolecules Using Alternating-Laser Excitation

Transcription activation by catabolite activator protein (CAP)

Highly efficient 5' capping of mitochondrial RNA with NAD + and NADH by yeast and human mitochondrial RNA polymerase

Systematic Structure-Activity Analysis of Microcin J25

The RNA Polymerase “Switch Region” Is a Target for Inhibitors

Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus

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