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Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus

Stem cell research, 2021-04, Vol.52, p.102240-102240, Article 102240

2021

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Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format

Journal of biomolecular screening, 2016-09, Vol.21 (8), p.804-815

2016

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Overexpression of Tau Protein Inhibits Kinesin-Dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease

The Journal of cell biology, 1998-11, Vol.143 (3), p.777-794

1998

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Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles

Journal of cell science, 1999-07, Vol.112 ( Pt 14) (14), p.2355-2367

1999

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Screening lead compounds for QT interval prolongation

Drug Discovery Today, 2001-01, Vol.6 (2), p.78-84

2001

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Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Neuron (Cambridge, Mass.), 2017-03, Vol.93 (5), p.1066-1081.e8

2017

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Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition

Journal of biomolecular screening, 2005-06, Vol.10 (4), p.339-347

2005

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MARK4 Is a Novel Microtubule-associated Proteins/Microtubule Affinity-regulating Kinase That Binds to the Cellular Microtubule Network and to Centrosomes

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.5915-5923

2004

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MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

Cell, 1997-04, Vol.89 (2), p.297-308

1997

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MAPs, MARKs and microtubule dynamics

Trends in biochemical sciences (Amsterdam. Regular ed.), 1998-08, Vol.23 (8), p.307-311

1998

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Ion channel screening technologies: will they revolutionize drug discovery?

Drug discovery today, 2002-02, Vol.7 (4), p.227-227

Ebneth, Andreas

2002

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Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics

Journal of molecular medicine (Berlin, Germany), 2002-08, Vol.80 (8), p.524-532

2002

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Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells

Cell motility and the cytoskeleton, 1999-11, Vol.44 (3), p.209-224

1999

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Differential cross section of the 2H(n, nnp)-reaction at En = 13MeV

Nuclear physics. A, 1989-09, Vol.501 (1), p.51-85

1989

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Does a synthetic peptide containing the leucine-zipper domain of c-myb form an α-helical structure in solution?

FEBS letters, 1994-01, Vol.337 (3), p.265-268

1994

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Biophysical characterization of the c-myb DNA-binding domain

Biochemistry (Easton), 1994-12, Vol.33 (48), p.14586-14593

1994

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HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery

Current opinion in drug discovery & development, 2003-07, Vol.6 (4), p.462

2003

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Differential cross section of the 2H(n, nnp)-reaction at En = 13 MeV

Nuclear physics. A, 1989, Vol.501 (1), p.51-85

1989

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Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch

Stem cell research, 2024-06, Vol.77, p.103414, Article 103414

2024

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Deploying human pluripotent stem cells to treat central nervous system disorders: facts, challenges and realising the potential

Stem cell research, 2019-12, Vol.41, p.101581-101581, Article 101581

2019

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Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study

PloS one, 2015-04, Vol.10 (4), p.e0123527-e0123527

2015

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The EBiSC iPSC bank for disease studies

Stem cell research, 2020-12, Vol.49, p.102034-102034, Article 102034

2020

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Human iPSC‐microglia expressing TREM2 p.R47H risk variant for Alzheimer’s disease do not show a loss‐of‐function phenotype

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

iScience, 2019-09, Vol.19, p.110-118

2019

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Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies

Stem cell research, 2021-07, Vol.54, p.102386-102386, Article 102386

2021

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Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus

Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format

Overexpression of Tau Protein Inhibits Kinesin-Dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease

Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles

Screening lead compounds for QT interval prolongation

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition

MARK4 Is a Novel Microtubule-associated Proteins/Microtubule Affinity-regulating Kinase That Binds to the Cellular Microtubule Network and to Centrosomes

MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

MAPs, MARKs and microtubule dynamics

Ion channel screening technologies: will they revolutionize drug discovery?

Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics

Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells

Differential cross section of the 2H(n, nnp)-reaction at En = 13MeV

Does a synthetic peptide containing the leucine-zipper domain of c-myb form an α-helical structure in solution?

Biophysical characterization of the c-myb DNA-binding domain

HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery

Differential cross section of the 2H(n, nnp)-reaction at En = 13 MeV

Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch

Deploying human pluripotent stem cells to treat central nervous system disorders: facts, challenges and realising the potential

Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study

The EBiSC iPSC bank for disease studies

Human iPSC‐microglia expressing TREM2 p.R47H risk variant for Alzheimer’s disease do not show a loss‐of‐function phenotype

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies

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