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Treating sickle cell disease by targeting HbS polymerization

Blood, 2017-05, Vol.129 (20), p.2719-2726

2017

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Protein folding transition path times from single molecule FRET

Current opinion in structural biology, 2018-02, Vol.48, p.30-39

2018

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Native contacts determine protein folding mechanisms in atomistic simulations

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17874-17879

2013

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Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times

Science (American Association for the Advancement of Science), 2012-02, Vol.335 (6071), p.981-984

2012

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Structural origin of slow diffusion in protein folding

Science (American Association for the Advancement of Science), 2015-09, Vol.349 (6255), p.1504-1510

2015

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Comparing a simple theoretical model for protein folding with all-atom molecular dynamics simulations

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17880-17885

2013

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Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (29), p.11837-11844

2009

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Drug discovery by a basic research scientist

Frontiers in molecular biosciences, 2022-11, Vol.9, p.1062346-1062346

Eaton, William A.

2022

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Measuring internal friction of an ultrafast-folding protein

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18320-18325

2008

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Modern Kinetics and Mechanism of Protein Folding: A Retrospective

The journal of physical chemistry. B, 2021-04, Vol.125 (14), p.3452-3467

Eaton, William A

2021

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Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models

Biophysical journal, 2015-09, Vol.109 (6), p.1264-1272

2015

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Chemical physics of protein folding

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (44), p.17770-17771

2012

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Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease

Haematologica (Roma), 2024-08, Vol.109 (8), p.2639

2024

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Solution Structure of the ESCRT-I and -II Supercomplex: Implications for Membrane Budding and Scission

Structure (London), 2012-05, Vol.20 (5), p.874-886

2012

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Experimental basis for a new allosteric model for multisubunit proteins

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (35), p.12758-12763

2014

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A retrospective on statistical mechanical models for hemoglobin allostery

The Journal of chemical physics, 2022-11, Vol.157 (18), p.184104-184104

Eaton, William A.

2022

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Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (5), p.1528-1533

2007

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Single-molecule fluorescence probes dynamics of barrier crossing

Nature (London), 2013-10, Vol.502 (7473), p.685-688

2013

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Chemical, physical, and theoretical kinetics of an ultrafast folding protein

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (48), p.18655-18662

2008

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Polyproline and the "Spectroscopic Ruler" Revisited with Single-Molecule Fluorescence

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (8), p.2754-2759

2005

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Single-Molecule Measurement of Protein Folding Kinetics

Science (American Association for the Advancement of Science), 2003-08, Vol.301 (5637), p.1233-1235

2003

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Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9437-9442

2011

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Impact of hemoglobin biophysical studies on molecular pathogenesis and drug therapy for sickle cell disease

Molecular aspects of medicine, 2022-04, Vol.84, p.100971-100971, Article 100971

Eaton, William A.

2022

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Effect of flexibility and cis residues in single-molecule FRET studies of polyproline

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (48), p.18964-18969

2007

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Hemoglobin S polymerization and sickle cell disease: A retrospective on the occasion of the 70th anniversary of Pauling's Science paper

American journal of hematology, 2020-02, Vol.95 (2), p.205-211

Eaton, William A.

2020

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Treating sickle cell disease by targeting HbS polymerization

Protein folding transition path times from single molecule FRET

Native contacts determine protein folding mechanisms in atomistic simulations

Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times

Structural origin of slow diffusion in protein folding

Comparing a simple theoretical model for protein folding with all-atom molecular dynamics simulations

Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

Drug discovery by a basic research scientist

Measuring internal friction of an ultrafast-folding protein

Modern Kinetics and Mechanism of Protein Folding: A Retrospective

Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models

Chemical physics of protein folding

Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease

Solution Structure of the ESCRT-I and -II Supercomplex: Implications for Membrane Budding and Scission

Experimental basis for a new allosteric model for multisubunit proteins

A retrospective on statistical mechanical models for hemoglobin allostery

Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations

Single-molecule fluorescence probes dynamics of barrier crossing

Chemical, physical, and theoretical kinetics of an ultrafast folding protein

Polyproline and the "Spectroscopic Ruler" Revisited with Single-Molecule Fluorescence

Single-Molecule Measurement of Protein Folding Kinetics

Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy

Impact of hemoglobin biophysical studies on molecular pathogenesis and drug therapy for sickle cell disease

Effect of flexibility and cis residues in single-molecule FRET studies of polyproline

Hemoglobin S polymerization and sickle cell disease: A retrospective on the occasion of the 70th anniversary of Pauling's Science paper

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