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Structural biology of the purine biosynthetic pathway

Cellular and molecular life sciences : CMLS, 2008-11, Vol.65 (23), p.3699-3724

2008

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Structural analyses reveal two distinct families of nucleoside phosphorylases

Biochemical journal, 2002-01, Vol.361 (Pt 1), p.1-25

2002

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Structure of the Escherichia coli ThiS−ThiF Complex, a Key Component of the Sulfur Transfer System in Thiamin Biosynthesis

Biochemistry (Easton), 2006-01, Vol.45 (1), p.11-19

2006

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Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis

Biochemistry (Easton), 2005-05, Vol.44 (21), p.7632-7643

2005

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Structural Insights into the Mechanism of the PLP Synthase Holoenzyme from Thermotoga maritima

Biochemistry (Easton), 2006-12, Vol.45 (49), p.14609-14620

2006

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Structural biology of enzymes of the thiamin biosynthesis pathway

Current opinion in structural biology, 2003-12, Vol.13 (6), p.739-747

2003

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The Crystal Structure and Mechanism of Orotidine 5′-monophosphate Decarboxylase

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (5), p.2005-2010

2000

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Enzymatic reactions involving novel mechanisms of carbanion stabilization

Current opinion in chemical biology, 2004-10, Vol.8 (5), p.508-515

2004

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Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis

Biochemistry (Easton), 2003-03, Vol.42 (10), p.2971-2981

2003

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Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase

The Journal of biological chemistry, 2003-11, Vol.278 (47), p.47110-47118

2003

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Structural Characterization of the Regulatory Proteins TenA and TenI from Bacillus subtilis and Identification of TenA as a Thiaminase II

Biochemistry (Easton), 2005-02, Vol.44 (7), p.2319-2329

2005

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Advances in multiple wavelength anomalous diffraction crystallography

Current Opinion in Chemical Biology, 2000-10, Vol.4 (5), p.495-499

Ealick, Steven E

2000

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Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray Crystallography

Biochemistry (Easton), 2004-08, Vol.43 (32), p.10328-10342

2004

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Thiamin biosynthesis in prokaryotes

Archives of microbiology, 1999-04, Vol.171 (5), p.293-300

1999

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Structures of Purine 2‘-Deoxyribosyltransferase, Substrate Complexes, and the Ribosylated Enzyme Intermediate at 2.0 Å Resolution

Biochemistry (Easton), 2004-03, Vol.43 (9), p.2384-2393

2004

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Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica: Implications for the Evolution of the Ribokinase Superfamily

Structure (London), 2004-10, Vol.12 (10), p.1809-1821

2004

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Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily

Biochemistry (Easton), 2006-12, Vol.45 (50), p.14880-14895

2006

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The Crystal Structure of 5′-Deoxy-5′-methylthioadenosine Phosphorylase II from Sulfolobus solfataricus, a Thermophilic Enzyme Stabilized by Intramolecular Disulfide Bonds

Journal of molecular biology, 2006-03, Vol.357 (1), p.252-262

2006

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The Mechanism of Inactivation of 3-Hydroxyanthranilate-3,4-dioxygenase by 4-Chloro-3-hydroxyanthranilate

Biochemistry (Easton), 2005-05, Vol.44 (21), p.7623-7631

2005

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Modular evolution of the purine biosynthetic pathway

Current Opinion in Chemical Biology, 2000-10, Vol.4 (5), p.567-572

2000

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PNP anticancer gene therapy

Current topics in medicinal chemistry, 2005-10, Vol.5 (13), p.1259

2005

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A Novel Function for the N-Terminal Nucleophile Hydrolase Fold Demonstrated by the Structure of an Archaeal Inosine Monophosphate Cyclohydrolase

Biochemistry (Easton), 2007-05, Vol.46 (17), p.5050-5062

2007

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Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Journal of molecular biology, 2000-05, Vol.298 (5), p.875-893

2000

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Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11735-11748

1997

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Gene Identification and Structural Characterization of the Pyridoxal 5‘-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099

Biochemistry (Easton), 2007-11, Vol.46 (47), p.13606-13615

2007

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Structural biology of the purine biosynthetic pathway

Structural analyses reveal two distinct families of nucleoside phosphorylases

Structure of the Escherichia coli ThiS−ThiF Complex, a Key Component of the Sulfur Transfer System in Thiamin Biosynthesis

Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis

Structural Insights into the Mechanism of the PLP Synthase Holoenzyme from Thermotoga maritima

Structural biology of enzymes of the thiamin biosynthesis pathway

The Crystal Structure and Mechanism of Orotidine 5′-monophosphate Decarboxylase

Enzymatic reactions involving novel mechanisms of carbanion stabilization

Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis

Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase

Structural Characterization of the Regulatory Proteins TenA and TenI from Bacillus subtilis and Identification of TenA as a Thiaminase II

Advances in multiple wavelength anomalous diffraction crystallography

Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray Crystallography

Thiamin biosynthesis in prokaryotes

Structures of Purine 2‘-Deoxyribosyltransferase, Substrate Complexes, and the Ribosylated Enzyme Intermediate at 2.0 Å Resolution

Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica: Implications for the Evolution of the Ribokinase Superfamily

Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily

The Crystal Structure of 5′-Deoxy-5′-methylthioadenosine Phosphorylase II from Sulfolobus solfataricus, a Thermophilic Enzyme Stabilized by Intramolecular Disulfide Bonds

The Mechanism of Inactivation of 3-Hydroxyanthranilate-3,4-dioxygenase by 4-Chloro-3-hydroxyanthranilate

Modular evolution of the purine biosynthetic pathway

PNP anticancer gene therapy

A Novel Function for the N-Terminal Nucleophile Hydrolase Fold Demonstrated by the Structure of an Archaeal Inosine Monophosphate Cyclohydrolase

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Gene Identification and Structural Characterization of the Pyridoxal 5‘-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099

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