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The T-body approach: redirecting T cells with antibody specificity

Handbook of experimental pharmacology, 2008 (181), p.329

Eshhar, Z

2008

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Development of adoptive cell therapy for cancer: a clinical perspective

Human gene therapy, 2010-06, Vol.21 (6), p.665

2010

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Expression of Immunoglobulin-T-Cell Receptor Chimeric Molecules as Functional Receptors with Antibody-Type Specificity

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (24), p.10024-10028

1989

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Specific Activation and Targeting of Cytotoxic Lymphocytes Through Chimeric Single Chains Consisting of Antibody-Binding Domains and the γ or ζ Subunits of the Immunoglobulin and T-Cell Receptors

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (2), p.720-724

1993

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Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR

Gene therapy, 2000-08, Vol.7 (16), p.1369-1377

2000

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In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (15), p.3369-3373

1995

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ErbB2 IS A TUMOR ASSOCIATED ANTIGEN AND A SUITABLE THERAPEUTIC TARGET IN WILMS TUMOR

The Journal of urology, 2004-10, Vol.172 (4), p.1644-1648

2004

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Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: Membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion

Cancer research (Chicago, Ill.), 2004-08, Vol.64 (16), p.5779-5786

2004

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WISH-PC2 : A unique xenograft model of human prostatic small cell carcinoma

Cancer research (Chicago, Ill.), 2000-12, Vol.60 (23), p.6563-6567

2000

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Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain

The Journal of experimental medicine, 1993-07, Vol.178 (1), p.361-366

1993

Volltextzugriff (PDF)

Crystal Structure of the Complex of a Catalytic Antibody Fab Fragment with a Transition State Analog: Structural Similarities in Esterase-Like Catalytic Antibodies

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (25), p.11721-11725

1995

Volltextzugriff (PDF)

P12.05 Evaluating the compatibility of tumor treating electric fields with key antitumoral immune functions

Neuro-oncology (Charlottesville, Va.), 2019-09, Vol.21 (Supplement_3), p.iii60-iii60

2019

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Tumor-specific T-bodies: towards clinical application

Cancer Immunology, Immunotherapy, 1997-11, Vol.45 (3-4), p.131-136

ESHHAR, Z

1997

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X-Ray Structures of a Hydrolytic Antibody and of Complexes Elucidate Catalytic Pathway from Substrate Binding and Transition State Stabilization through Water Attack and Product Release

Proceedings of the National Academy of Sciences - PNAS, 1997-07, Vol.94 (15), p.7857-7861

1997

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Unexpectedly high occurrence of catalytic antibodies in MRL/lpr and SJL mice immunized with a transition-state analog: is there a linkage to autoimmunity?

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (6), p.2145-2149

1995

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catELISA: A Facile General Route to Catalytic Antibodies

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (2), p.373-377

1993

Volltextzugriff (PDF)

Photodynamic therapy with Pd‐bacteriopheophorbide (TOOKAD): Successful in vivo treatment of human prostatic small cell carcinoma xenografts

International journal of cancer, 2003-05, Vol.104 (6), p.782-789

2003

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Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation

Blood, 2005-04, Vol.105 (8), p.3087-3093

2005

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T-bodies as antiviral agents

Current topics in microbiology and immunology, 2001, Vol.260, p.271

2001

Volltextzugriff (PDF)

Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft

Cancer research (Chicago, Ill.), 2002-12, Vol.62 (23), p.6803-6807

2002

Volltextzugriff (PDF)

Fine specificity of the IgE interaction with the low and high affinity Fc receptor

The Journal of immunology (1950), 1993-02, Vol.150 (4), p.1365

1993

Volltextzugriff (PDF)

Generation of effector T cells expressing chimeric T cell receptor with antibody type-specificity

Transplantation proceedings, 1989-02, Vol.21 (1 Pt 1), p.127-130

1989

Volltextzugriff (PDF)

Functional expression of chimeric receptor genes in human T cells

Journal of Immunological Methods, 2001-02, Vol.248 (1), p.67-76

2001

Volltextzugriff (PDF)

Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.8503-8512

2005

Volltextzugriff (PDF)

Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes

The Journal of clinical investigation, 2004-12, Vol.114 (12), p.1774-1781

2004

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The T-body approach: redirecting T cells with antibody specificity

Development of adoptive cell therapy for cancer: a clinical perspective

Expression of Immunoglobulin-T-Cell Receptor Chimeric Molecules as Functional Receptors with Antibody-Type Specificity

Specific Activation and Targeting of Cytotoxic Lymphocytes Through Chimeric Single Chains Consisting of Antibody-Binding Domains and the γ or ζ Subunits of the Immunoglobulin and T-Cell Receptors

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR

In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes

ErbB2 IS A TUMOR ASSOCIATED ANTIGEN AND A SUITABLE THERAPEUTIC TARGET IN WILMS TUMOR

Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: Membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion

WISH-PC2 : A unique xenograft model of human prostatic small cell carcinoma

Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain

Crystal Structure of the Complex of a Catalytic Antibody Fab Fragment with a Transition State Analog: Structural Similarities in Esterase-Like Catalytic Antibodies

P12.05 Evaluating the compatibility of tumor treating electric fields with key antitumoral immune functions

Tumor-specific T-bodies: towards clinical application

X-Ray Structures of a Hydrolytic Antibody and of Complexes Elucidate Catalytic Pathway from Substrate Binding and Transition State Stabilization through Water Attack and Product Release

Unexpectedly high occurrence of catalytic antibodies in MRL/lpr and SJL mice immunized with a transition-state analog: is there a linkage to autoimmunity?

catELISA: A Facile General Route to Catalytic Antibodies

Photodynamic therapy with Pd‐bacteriopheophorbide (TOOKAD): Successful in vivo treatment of human prostatic small cell carcinoma xenografts

Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation

T-bodies as antiviral agents

Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft

Fine specificity of the IgE interaction with the low and high affinity Fc receptor

Generation of effector T cells expressing chimeric T cell receptor with antibody type-specificity

Functional expression of chimeric receptor genes in human T cells

Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity

Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes

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