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AMPK Enhances Insulin-Stimulated GLUT4 Regulation via Lowering Membrane Cholesterol

Endocrinology (Philadelphia), 2012-05, Vol.153 (5), p.2130-2141

2012

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Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet

American journal of physiology: endocrinology and metabolism, 2019-08, Vol.317 (2), p.E362-E373

2019

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Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

The Journal of cell biology, 2011-04, Vol.193 (1), p.185-199

2011

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Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis

Frontiers in endocrinology (Lausanne), 2022-02, Vol.13, p.821849-821849

2022

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Chromium Activates Glucose Transporter 4 Trafficking and Enhances Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes via a Cholesterol-Dependent Mechanism

Molecular endocrinology (Baltimore, Md.), 2006-04, Vol.20 (4), p.857-870

2006

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An early, reversible cholesterolgenic etiology of diet-induced insulin resistance

Molecular metabolism (Germany), 2023-06, Vol.72, p.101715-101715, Article 101715

2023

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Type 2 diabetes mellitus and cerebrospinal fluid Alzheimer's disease biomarker amyloid β1-42 in Alzheimer's Disease Neuroimaging Initiative participants

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2018, Vol.10 (1), p.94-98

2018

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Disruption of Cortical Actin in Skeletal Muscle Demonstrates an Essential Role of the Cytoskeleton in Glucose Transporter 4 Translocation in Insulin-sensitive Tissues

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40699-40706

2004

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Phosphatidylinositol 4,5-Bisphosphate Reverses Endothelin-1–Induced Insulin Resistance via an Actin-Dependent Mechanism

Diabetes (New York, N.Y.), 2005-06, Vol.54 (6), p.1698-1705

2005

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Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells

Biochemical pharmacology, 2014-11, Vol.92 (2), p.380-388

2014

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Chromium enhances insulin responsiveness via AMPK

The Journal of nutritional biochemistry, 2014-05, Vol.25 (5), p.565-572

2014

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Protective Effect of Phosphatidylinositol 4,5-Bisphosphate against Cortical Filamentous Actin Loss and Insulin Resistance Induced by Sustained Exposure of 3T3-L1 Adipocytes to Insulin

The Journal of biological chemistry, 2004-09, Vol.279 (38), p.39705-39709

2004

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The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)–mediated glucose uptake into skeletal muscle cells

The Journal of biological chemistry, 2017-11, Vol.292 (46), p.19034-19043

2017

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Fretting about fat: a new look at the lipid droplet surface and the roundabout role of Plin2 in cellular lipid storage: focus on "Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis"

American Journal of Physiology: Cell Physiology, 2012-10, Vol.303 (7), p.C713-C714

Elmendorf, Jeffrey S

2012

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Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis

Trends in endocrinology and metabolism, 2011-03, Vol.22 (3), p.110-116

2011

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Hexosamine Biosynthesis Pathway Flux Contributes to Insulin Resistance via Altering Membrane Phosphatidylinositol 4,5-Bisphosphate and Cortical Filamentous Actin

Endocrinology (Philadelphia), 2009-04, Vol.150 (4), p.1636-1645

2009

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266-LB: Evidence for a Hexosamine Biosynthesis Pathway-Mediated Sp1 Cholesterolgenic Response Being an Early Etiological Factor of Insulin Resistance

Diabetes (New York, N.Y.), 2019-06, Vol.68 (Supplement_1)

2019

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Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c

FEBS letters, 2003-01, Vol.534 (1), p.54-60

2003

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Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report

Arteriosclerosis, thrombosis, and vascular biology, 2011-05, Vol.31 (5), p.1139-1140

2011

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Hexosamine Biosynthesis Impairs Insulin Action via a Cholesterolgenic Response

Molecular endocrinology (Baltimore, Md.), 2013-03, Vol.27 (3), p.536-547

2013

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Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism

American Journal of Physiology: Cell Physiology, 2004-02, Vol.286 (2), p.C317-C329

2004

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Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western‐style high‐fat diet

Physiological reports, 2017-08, Vol.5 (16), p.e13363-n/a

2017

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Evidence Coupling Increased Hexosamine Biosynthesis Pathway Activity to Membrane Cholesterol Toxicity and Cortical Filamentous Actin Derangement Contributing to Cellular Insulin Resistance

Endocrinology (Philadelphia), 2011-09, Vol.152 (9), p.3373-3384

2011

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Calmodulin Antagonists Inhibit Insulin-Stimulated GLUT4 (Glucose Transporter 4) Translocation by Preventing the Formation of Phosphatidylinositol 3,4,5-Trisphosphate in 3T3L1 Adipocytes

Molecular endocrinology (Baltimore, Md.), 2000-02, Vol.14 (2), p.317-326

2000

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Effect of Corncob Bedding on Feed Conversion Efficiency in a High-Fat Diet-Induced Prediabetic Model in C57Bl/6J Mice

Journal of the American Association for Laboratory Animal Science, 2014-09, Vol.53 (5), p.449-451

2014

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AMPK Enhances Insulin-Stimulated GLUT4 Regulation via Lowering Membrane Cholesterol

Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis

Chromium Activates Glucose Transporter 4 Trafficking and Enhances Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes via a Cholesterol-Dependent Mechanism

An early, reversible cholesterolgenic etiology of diet-induced insulin resistance

Type 2 diabetes mellitus and cerebrospinal fluid Alzheimer's disease biomarker amyloid β1-42 in Alzheimer's Disease Neuroimaging Initiative participants

Disruption of Cortical Actin in Skeletal Muscle Demonstrates an Essential Role of the Cytoskeleton in Glucose Transporter 4 Translocation in Insulin-sensitive Tissues

Phosphatidylinositol 4,5-Bisphosphate Reverses Endothelin-1–Induced Insulin Resistance via an Actin-Dependent Mechanism

Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells

Chromium enhances insulin responsiveness via AMPK

Protective Effect of Phosphatidylinositol 4,5-Bisphosphate against Cortical Filamentous Actin Loss and Insulin Resistance Induced by Sustained Exposure of 3T3-L1 Adipocytes to Insulin

The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)–mediated glucose uptake into skeletal muscle cells

Fretting about fat: a new look at the lipid droplet surface and the roundabout role of Plin2 in cellular lipid storage: focus on "Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis"

Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis

Hexosamine Biosynthesis Pathway Flux Contributes to Insulin Resistance via Altering Membrane Phosphatidylinositol 4,5-Bisphosphate and Cortical Filamentous Actin

266-LB: Evidence for a Hexosamine Biosynthesis Pathway-Mediated Sp1 Cholesterolgenic Response Being an Early Etiological Factor of Insulin Resistance

Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c

Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report

Hexosamine Biosynthesis Impairs Insulin Action via a Cholesterolgenic Response

Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism

Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western‐style high‐fat diet

Evidence Coupling Increased Hexosamine Biosynthesis Pathway Activity to Membrane Cholesterol Toxicity and Cortical Filamentous Actin Derangement Contributing to Cellular Insulin Resistance

Calmodulin Antagonists Inhibit Insulin-Stimulated GLUT4 (Glucose Transporter 4) Translocation by Preventing the Formation of Phosphatidylinositol 3,4,5-Trisphosphate in 3T3L1 Adipocytes

Effect of Corncob Bedding on Feed Conversion Efficiency in a High-Fat Diet-Induced Prediabetic Model in C57Bl/6J Mice

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