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Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Cell death and differentiation, 2004-04, Vol.11 (4), p.424-438

2004

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Kennedy's disease : Caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

Journal of neurochemistry, 1999, Vol.72 (1), p.185-195

1999

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Shift of the Cellular Oxidation‐Reduction Potential in Neural Cells Expressing Bcl‐2

Journal of neurochemistry, 1996-09, Vol.67 (3), p.1259-1267

1996

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Calpain Activation in Huntington's Disease

The Journal of neuroscience, 2002-06, Vol.22 (12), p.4842-4849

2002

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Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

The Journal of biological chemistry, 2001-09, Vol.276 (36), p.33869

2001

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Anti-cancer activity of targeted pro-apoptotic peptides

Nature medicine, 1999-09, Vol.5 (9), p.1032-1038

1999

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Yeast and Mammalian Metallothioneins Functionally Substitute for Yeast Copper-Zinc Superoxide Dismutase

Proceedings of the National Academy of Sciences - PNAS, 1993-09, Vol.90 (17), p.8013-8017

1993

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Encapsulation of Proteins in Transparent Porous Silicate Glasses Prepared by the Sol-Gel Method

Science (American Association for the Advancement of Science), 1992-02, Vol.255 (5048), p.1113-1115

1992

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Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.20211-20220

2004

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Pro-caspase-3 Is a Major Physiologic Target of Caspase-8

The Journal of biological chemistry, 1998-10, Vol.273 (42), p.27084-27090

1998

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Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease

The Journal of neuroscience, 2002-09, Vol.22 (18), p.7862-7872

2002

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Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

The Journal of biological chemistry, 2001-02, Vol.276 (5), p.3149-3157

2001

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Release of Caspase-9 from Mitochondria during Neuronal Apoptosis and Cerebral Ischemia

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (10), p.5752-5757

1999

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Mutations in Copper-Zinc Superoxide Dismutase that Cause Amyotrophic Lateral Sclerosis Alter the Zinc Binding Site and the Redox Behavior of the Protein

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (22), p.12240-12244

1996

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Androgen Receptor YAC Transgenic Mice Recapitulate SBMA Motor Neuronopathy and Implicate VEGF164 in the Motor Neuron Degeneration

Neuron (Cambridge, Mass.), 2004-03, Vol.41 (5), p.687-699

2004

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A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

Nature medicine, 2000-04, Vol.6 (4), p.397-404

2000

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Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.9158-9167

1998

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Neurotrophin dependence domain: a domain required for the mediation of apoptosis by the p75 neurotrophin receptor

Journal of molecular neuroscience, 2000-12, Vol.15 (3), p.215-230

2000

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Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases

The Journal of neuroscience, 1997-08, Vol.17 (16), p.6165-6178

1997

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Nuclear Localization of a Non-caspase Truncation Product of Atrophin-1, with an Expanded Polyglutamine Repeat, Increases Cellular Toxicity

The Journal of biological chemistry, 2003-04, Vol.278 (15), p.13047-13055

2003

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Determinants of cytochrome c pro-apoptotic activity. The role of lysine 72 trimethylation

The Journal of biological chemistry, 2000-05, Vol.275 (21), p.16127-16133

2000

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Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?

Annals of neurology, 1997-08, Vol.42 (2), p.135-137

1997

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Effect of overexpression of Bcl-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome

Free radical biology & medicine, 2001-12, Vol.31 (12), p.1550-1559

2001

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The role of lysine-234 in .beta.-lactamase catalysis probed by site-directed mutagenesis

Biochemistry (Easton), 1990-06, Vol.29 (24), p.5797-5806

1990

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Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild-Type Yeast

The Journal of cell biology, 1997-06, Vol.137 (7), p.1581-1588

1997

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Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Kennedy's disease : Caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

Shift of the Cellular Oxidation‐Reduction Potential in Neural Cells Expressing Bcl‐2

Calpain Activation in Huntington's Disease

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

Anti-cancer activity of targeted pro-apoptotic peptides

Yeast and Mammalian Metallothioneins Functionally Substitute for Yeast Copper-Zinc Superoxide Dismutase

Encapsulation of Proteins in Transparent Porous Silicate Glasses Prepared by the Sol-Gel Method

Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus

Pro-caspase-3 Is a Major Physiologic Target of Caspase-8

Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

Release of Caspase-9 from Mitochondria during Neuronal Apoptosis and Cerebral Ischemia

Mutations in Copper-Zinc Superoxide Dismutase that Cause Amyotrophic Lateral Sclerosis Alter the Zinc Binding Site and the Redox Behavior of the Protein

Androgen Receptor YAC Transgenic Mice Recapitulate SBMA Motor Neuronopathy and Implicate VEGF164 in the Motor Neuron Degeneration

A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Neurotrophin dependence domain: a domain required for the mediation of apoptosis by the p75 neurotrophin receptor

Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases

Nuclear Localization of a Non-caspase Truncation Product of Atrophin-1, with an Expanded Polyglutamine Repeat, Increases Cellular Toxicity

Determinants of cytochrome c pro-apoptotic activity. The role of lysine 72 trimethylation

Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?

Effect of overexpression of Bcl-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome

The role of lysine-234 in .beta.-lactamase catalysis probed by site-directed mutagenesis

Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild-Type Yeast

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