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Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia

British journal of pharmacology, 2009-11, Vol.158 (5), p.1183-1195

2009

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Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

Oncogene, 2004-05, Vol.23 (25), p.4400-4412

2004

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Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins

Molecular and Cellular Biology, 2004-07, Vol.24 (14), p.6393-6402

2004

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Phase 1b multi-indication study of the antibody drug conjugate anetumab ravtansine in patients with mesothelin-expressing advanced or recurrent malignancies

Annals of oncology, 2017-09, Vol.28, p.v141-v141

2017

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P1.04-013 Phase 1b Multi-Indication Study of the Antibody Drug Conjugate Anetumab Ravtansine in Patients with Mesothelin-Expressing Advanced or Recurrent Malignancies

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S1977-S1977

2017

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Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer

Oncogene, 2005-07, Vol.24 (31), p.4934-4945

2005

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372 Safety and activity of the anti-mesothelin antibody–drug conjugate anetumab ravtansine in combination with pegylated-liposomal doxorubicin in platinum-resistant ovarian, fallopian tube or primary peritoneal cancer

International journal of gynecological cancer, 2020-11, Vol.30 (Suppl 3), p.A154-A154

2020

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Molecular Chaperones Function as Steroid Receptor Nuclear Mobility Factors

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.2876-2881

2004

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Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro

Molecular and Cellular Biology, 2005-03, Vol.25 (6), p.2406-2418

2005

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Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer

Cancer research (Chicago, Ill.), 2004-04, Vol.64 (7), p.2365-2370

2004

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OA 02.01 Randomized Phase II Study of Anetumab Ravtansine or Vinorelbine in Patients with Metastatic Pleural Mesothelioma

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S1746-S1746

2017

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Recruitment of dioxin receptor to active transcription sites

Molecular biology of the cell, 2002-06, Vol.13 (6), p.2001-2015

2002

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Molecular Cloning and Characterization of STAMP1, a Highly Prostate-specific Six Transmembrane Protein that Is Overexpressed in Prostate Cancer

The Journal of biological chemistry, 2002-09, Vol.277 (39), p.36689-36696

2002

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Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage

Oncogene, 2004-01, Vol.23 (1), p.49-57

2004

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Trafficking of nuclear receptors in living cells

Journal of steroid biochemistry and molecular biology, 2000-11, Vol.74 (5), p.249-254

2000

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Chromatin dynamics and the evolution of alternate promoter states

Chromosome research, 2006-02, Vol.14 (1), p.107-116

2006

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Protein dynamics in the nuclear compartment

Current Opinion in Genetics & Development, 2002-04, Vol.12 (2), p.137-141

2002

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Inducer-dependent transcriptional activation of the P4501A2 gene in vivo and in isolated hepatocytes

The Journal of biological chemistry, 1993-01, Vol.268 (2), p.1053-1057

1993

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Subnuclear Trafficking and Gene Targeting by Steroid Receptors

Annals of the New York Academy of Sciences, 2004-06, Vol.1024 (1), p.213-220

2004

Volltextzugriff (PDF)

Down-regulation of the Notch pathway mediated by a g-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia

British journal of pharmacology, 2009-11, Vol.158 (5), p.1183-1195

2009

Volltextzugriff (PDF)

First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors

Journal of clinical oncology, 2020-06, Vol.38 (16), p.1824-1835

2020

Volltextzugriff (PDF)

Developing a fit-for-purpose composite symptom score as a symptom burden endpoint for clinical trials in patients with malignant pleural mesothelioma

Scientific reports, 2024-06, Vol.14 (1), p.14839-10, Article 14839

2024

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Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

Cancer cell international, 2015-02, Vol.15 (1), p.14-14, Article 14

2015

Volltextzugriff (PDF)

The impact of physical and psychological comorbid conditions on the quality of life of patients with acute myocardial infarction: a multi-center, cross-sectional observational study from Turkey

International journal of psychiatry in medicine, 2013-01, Vol.45 (2), p.97

2013

Volltextzugriff (PDF)

Late breaking clinical trials 1

Clinical kidney journal, 2011-06, Vol.4 (suppl 2), p.4-4.s2.1

2011

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Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins

Phase 1b multi-indication study of the antibody drug conjugate anetumab ravtansine in patients with mesothelin-expressing advanced or recurrent malignancies

P1.04-013 Phase 1b Multi-Indication Study of the Antibody Drug Conjugate Anetumab Ravtansine in Patients with Mesothelin-Expressing Advanced or Recurrent Malignancies

Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer

372 Safety and activity of the anti-mesothelin antibody–drug conjugate anetumab ravtansine in combination with pegylated-liposomal doxorubicin in platinum-resistant ovarian, fallopian tube or primary peritoneal cancer

Molecular Chaperones Function as Steroid Receptor Nuclear Mobility Factors

Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro

Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer

OA 02.01 Randomized Phase II Study of Anetumab Ravtansine or Vinorelbine in Patients with Metastatic Pleural Mesothelioma

Recruitment of dioxin receptor to active transcription sites

Molecular Cloning and Characterization of STAMP1, a Highly Prostate-specific Six Transmembrane Protein that Is Overexpressed in Prostate Cancer

Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage

Trafficking of nuclear receptors in living cells

Chromatin dynamics and the evolution of alternate promoter states

Protein dynamics in the nuclear compartment

Inducer-dependent transcriptional activation of the P4501A2 gene in vivo and in isolated hepatocytes

Subnuclear Trafficking and Gene Targeting by Steroid Receptors

Down-regulation of the Notch pathway mediated by a g-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia

First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors

Developing a fit-for-purpose composite symptom score as a symptom burden endpoint for clinical trials in patients with malignant pleural mesothelioma

Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

The impact of physical and psychological comorbid conditions on the quality of life of patients with acute myocardial infarction: a multi-center, cross-sectional observational study from Turkey

Late breaking clinical trials 1

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