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Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase

PloS one, 2018-08, Vol.13 (8), p.e0202826

2018

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Effect of Mimetic CDK9 Inhibitors on HIV-1-Activated Transcription

Journal of molecular biology, 2013-02, Vol.425 (4), p.812-829

2013

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Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2017-11, Vol.213, p.55-80

el Kouni, Mahmoud H.

2017

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Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase

The international journal of biochemistry & cell biology, 2019-05, Vol.110, p.122-129

2019

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Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase

Neuroscience research, 2006-09, Vol.56 (1), p.111-118

2006

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Enzymes of pyrimidine salvage pathways in intraerythrocytic Plasmodium falciparum

The international journal of biochemistry & cell biology, 2018-12, Vol.105, p.115-122

2018

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Potential chemotherapeutic targets in the purine metabolism of parasites

Pharmacology & therapeutics (Oxford), 2003-09, Vol.99 (3), p.283-309

el Kouni, Mahmoud H

2003

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Isolation and substrate specificity of an adenine nucleoside phosphorylase from adult Schistosoma mansoni

Molecular and biochemical parasitology, 2014-03, Vol.194 (1-2), p.44-47

2014

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Uptake of Nitrobenzylthioinosine and Purine β-l-Nucleosides by Intracellular Toxoplasma gondii

Antimicrobial Agents and Chemotherapy, 2003-10, Vol.47 (10), p.3247-3251

2003

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Adenosine metabolism in Toxoplasma gondii: potential targets for chemotherapy

Current pharmaceutical design, 2007-02, Vol.13 (6), p.581-597

el Kouni, Mahmoud H

2007

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Nucleoside kinases in adult Schistosoma mansoni: Phosphorylation of pyrimidine nucleosides

Molecular and biochemical parasitology, 2014-03, Vol.194 (1-2), p.53-55

2014

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Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2015-10, Vol.188, p.63-69

2015

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Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii

Antimicrobial Agents and Chemotherapy, 1999-10, Vol.43 (10), p.2437-2443

1999

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Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Biochemical pharmacology, 2007-05, Vol.73 (10), p.1558-1572

2007

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Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

Arteriosclerosis, thrombosis, and vascular biology, 2010-12, Vol.30 (12), p.2631-2638

2010

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Trends in the design of nucleoside analogues as anti-HIV drugs

Current pharmaceutical design, 2002-01, Vol.8 (8), p.581-593

el Kouni, Mahmoud H

2002

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Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase

Journal of neurotrauma, 2008-06, Vol.25 (6), p.695-707

2008

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Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase

Acta crystallographica. Section D, Biological crystallography., 2007-02, Vol.63 (2), p.126-134

2007

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Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase

Bioorganic & medicinal chemistry, 2010-05, Vol.18 (10), p.3403-3412

2010

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Kinetic studies of thymidine phosphorylase from mouse liver

Biochemistry (Easton), 1985-11, Vol.24 (24), p.6799-6807

1985

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Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands of Toxoplasma gondii Adenosine Kinase

Journal of medicinal chemistry, 2008-07, Vol.51 (13), p.3934-3945

2008

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7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities

Biochemical pharmacology, 2008-10, Vol.76 (8), p.958-966

2008

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Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines

Acta crystallographica. Section D, Biological crystallography., 2005-07, Vol.61 (7), p.863-872

2005

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Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity

Antimicrobial Agents and Chemotherapy, 2000-04, Vol.44 (4), p.853-858

2000

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Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities

Biochemical pharmacology, 2010-10, Vol.80 (7), p.955-963

2010

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Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase

Effect of Mimetic CDK9 Inhibitors on HIV-1-Activated Transcription

Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets

Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase

Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase

Enzymes of pyrimidine salvage pathways in intraerythrocytic Plasmodium falciparum

Potential chemotherapeutic targets in the purine metabolism of parasites

Isolation and substrate specificity of an adenine nucleoside phosphorylase from adult Schistosoma mansoni

Uptake of Nitrobenzylthioinosine and Purine β-l-Nucleosides by Intracellular Toxoplasma gondii

Adenosine metabolism in Toxoplasma gondii: potential targets for chemotherapy

Nucleoside kinases in adult Schistosoma mansoni: Phosphorylation of pyrimidine nucleosides

Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine

Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii

Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

Trends in the design of nucleoside analogues as anti-HIV drugs

Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase

Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase

Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase

Kinetic studies of thymidine phosphorylase from mouse liver

Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands of Toxoplasma gondii Adenosine Kinase

7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities

Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines

Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity

Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities

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