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Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo

The Journal of steroid biochemistry and molecular biology, 2003-04, Vol.84 (5), p.555-562

2003

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Synthesis and Evaluation of Novel Steroidal Oxime Inhibitors of P450 17 (17α-Hydroxylase/C17−20-Lyase) and 5α-Reductase Types 1 and 2

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4266-4277

2000

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

Journal of enzyme inhibition and medicinal chemistry, 2004-02, Vol.19 (1), p.17-32

2004

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The unusual visual system of the Strepsiptera: external eye and neuropils

Journal of Comparative Physiology, 2003-08, Vol.189 (8), p.617-630

2003

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Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells

The Journal of steroid biochemistry and molecular biology, 2002-06, Vol.81 (2), p.173-179

2002

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Segregation of visual input to the mushroom bodies in the honeybee (Apis mellifera)

Journal of comparative neurology (1911), 2002-09, Vol.451 (4), p.362-373

2002

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Discovery of selective CYP11B2 (aldosterone synthase) inhibitors for the therapy of congestive heart failure and myocardial fibrosis

European journal of medicinal chemistry, 2003-04, Vol.38 (4), p.363-366

2003

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Mushroom body volumes and visual interneurons in ants: Comparison between sexes and castes

Journal of comparative neurology (1911), 2004-02, Vol.469 (2), p.198-213

2004

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Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,20-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome-P450-reductase in Escherichia coli

The Journal of steroid biochemistry and molecular biology, 2000-12, Vol.75 (1), p.57-63

2000

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Novel steroidal pyrimidyl inhibitors of P450 17 (17α-hydroxylase/C17-20-lyase)

Archiv der Pharmazie (Weinheim), 2001-12, Vol.334 (12), p.373-374

2001

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Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid chromatography/ion-trap mass spectrometry

Rapid communications in mass spectrometry, 2005-01, Vol.19 (8), p.1069-1074

2005

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Controlled multicentre study of the influence of subcutaneous recombinant human erythropoietin on anaemia and transfusion dependency in patients with ovarian carcinoma treated with platinum-based chemotherapy

Medical oncology (Northwood, London, England), 1998-09, Vol.15 (3), p.174-182

1998

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The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives

Biomedical chromatography, 2005-04, Vol.19 (3), p.245-249

2005

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Enantiomeric resolution of some human aldosterone synthase [CYP 11 B2] inhibitors on derivatized polysaccharide chiral stationary phases

Journal of separation science, 2003-10, Vol.26 (15-16), p.1455-1458

2003

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Chunk Versus Point Sampling: Visual Imaging in a Small Insect

Science (American Association for the Advancement of Science), 1999-11, Vol.286 (5442), p.1178-1180

1999

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Mushroom bodies of vespid wasps

Journal of comparative neurology (1911), 2000-01, Vol.416 (1), p.93-100

2000

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Orientation in the ant Paraponera clavata

Journal of insect behavior, 1999-09, Vol.12 (5), p.711-722

Ehmer, B

1999

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Recombinant Human Erythropoietin in the Anemia Associated With Multiple Myeloma or Non-Hodgkin’s Lymphoma: Dose Finding and Identification of Predictors of Response

Blood, 1995-12, Vol.86 (12), p.4446-4453, Article 4446

1995

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Mushroom Bodies of Vespid Wasps

Journal of comparative neurology (1911), 2000-01, Vol.416 (1), p.93-100

2000

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Proprioceptors and fast antennal reflexes in the ant Odontomachus (Formicidae, Ponerinae)

Cell and tissue research, 1997-10, Vol.290 (1), p.153-165

1997

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Single-dose Pharmacokinetics of Recombinant Human Erythropoietin in Patients with Various Degrees of Renal Failure

Nephrology, dialysis, transplantation, 1989, Vol.4 (5), p.345-349

1989

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Treatment of chronic stable angina with carvedilol in comparison with nifedipine s.r

European heart journal, 1991-01, Vol.12 (1), p.60

1991

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The clearance of a single i.v. bolus of recombinant human erythropoietin from the serum of patients with myelodysplastic syndromes and its effects on erythropoiesis

Experimental hematology, 1991-08, Vol.19 (7), p.613-616

1991

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Efficacy and Safety of Carvedilol in Comparison with Nifedipine Sustained-Release in Chronic Stable Angina

Journal of cardiovascular pharmacology, 1992, Vol.19 Suppl 1 (Supplement 1), p.S122-S127

1992

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Pharmacokinetics of recombinant human erythropoietin in dialysis patients after single and multiple subcutaneous administrations

Nephron (2015), 1992, Vol.61 (4), p.393

1992

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Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo

Synthesis and Evaluation of Novel Steroidal Oxime Inhibitors of P450 17 (17α-Hydroxylase/C17−20-Lyase) and 5α-Reductase Types 1 and 2

Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

The unusual visual system of the Strepsiptera: external eye and neuropils

Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells

Segregation of visual input to the mushroom bodies in the honeybee (Apis mellifera)

Discovery of selective CYP11B2 (aldosterone synthase) inhibitors for the therapy of congestive heart failure and myocardial fibrosis

Mushroom body volumes and visual interneurons in ants: Comparison between sexes and castes

Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,20-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome-P450-reductase in Escherichia coli

Novel steroidal pyrimidyl inhibitors of P450 17 (17α-hydroxylase/C17-20-lyase)

Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid chromatography/ion-trap mass spectrometry

Controlled multicentre study of the influence of subcutaneous recombinant human erythropoietin on anaemia and transfusion dependency in patients with ovarian carcinoma treated with platinum-based chemotherapy

The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives

Enantiomeric resolution of some human aldosterone synthase [CYP 11 B2] inhibitors on derivatized polysaccharide chiral stationary phases

Chunk Versus Point Sampling: Visual Imaging in a Small Insect

Mushroom bodies of vespid wasps

Orientation in the ant Paraponera clavata

Recombinant Human Erythropoietin in the Anemia Associated With Multiple Myeloma or Non-Hodgkin’s Lymphoma: Dose Finding and Identification of Predictors of Response

Mushroom Bodies of Vespid Wasps

Proprioceptors and fast antennal reflexes in the ant Odontomachus (Formicidae, Ponerinae)

Single-dose Pharmacokinetics of Recombinant Human Erythropoietin in Patients with Various Degrees of Renal Failure

Treatment of chronic stable angina with carvedilol in comparison with nifedipine s.r

The clearance of a single i.v. bolus of recombinant human erythropoietin from the serum of patients with myelodysplastic syndromes and its effects on erythropoiesis

Efficacy and Safety of Carvedilol in Comparison with Nifedipine Sustained-Release in Chronic Stable Angina

Pharmacokinetics of recombinant human erythropoietin in dialysis patients after single and multiple subcutaneous administrations

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