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Therapeutic drug monitoring of oral targeted antineoplastic drugs

European journal of clinical pharmacology, 2021-04, Vol.77 (4), p.441-464

2021

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Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides

Clinical pharmacology and therapeutics, 2021-07, Vol.110 (1), p.248-258

2021

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Perspectives on Model‐Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.29-36

2021

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Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

British journal of clinical pharmacology, 2019-01, Vol.85 (1), p.216-226

2019

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Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure

Clinical pharmacology and therapeutics, 2018-12, Vol.104 (6), p.1219-1228

2018

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Use of Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Axitinib Exposure: A Fresh Approach to Precision Dosing in Oncology

Journal of clinical pharmacology, 2019-06, Vol.59 (6), p.872-879

2019

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Evaluation of modafinil as a perpetrator of metabolic drug–drug interactions using a model informed cocktail reaction phenotyping trial protocol

British journal of clinical pharmacology, 2018-03, Vol.84 (3), p.501-509

2018

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Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries

European journal of clinical pharmacology, 2018-07, Vol.74 (7), p.913-920

2018

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Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years

Paediatric drugs, 2022-11, Vol.24 (6), p.603-655

2022

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Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges

Cancers, 2023-06, Vol.15 (13), p.3293

2023

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Kinase inhibitor pharmacokinetics: comprehensive summary and roadmap for addressing inter-individual variability in exposure

Expert opinion on drug metabolism & toxicology, 2017-01, Vol.13 (1), p.31-49

2017

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Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity

European journal of clinical pharmacology, 2019-09, Vol.75 (9), p.1211-1218

2019

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Combining Therapeutic Drug Monitoring and Pharmacokinetic Modelling Deconvolutes Physiological and Environmental Sources of Variability in Clozapine Exposure

Pharmaceutics, 2021-12, Vol.14 (1), p.47

2021

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Plasma concentration guided dosing of drugs used for the treatment of childhood leukaemias: protocol for a systematic review

BMJ open, 2022-01, Vol.12 (1), p.e053308-e053308

2022

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Cost-effectiveness of oral anticancer drugs and associated individualised dosing approaches in patients with cancer: protocol for a systematic review

BMJ open, 2021-08, Vol.11 (8), p.e047173-e047173

2021

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A novel approach for the simultaneous quantification of 18 small molecule kinase inhibitors in human plasma: A platform for optimised KI dosing

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-10, Vol.1033-1034, p.17-26

2016

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Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs

European journal of clinical pharmacology, 2021-04, Vol.77 (4), p.465-465

2021

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Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies

Pharmaceuticals (Basel, Switzerland), 2021-02, Vol.14 (2), p.115

2021

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Physiologically-based pharmacokinetic modeling as an approach to evaluate the effect of covariates and drug-drug interactions on variability in epidermal growth factor receptor kinase inhibitor exposure

Translational cancer research, 2017-12, Vol.6 (S10), p.S1600-S1612

2017

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Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups

Cancers, 2021-05, Vol.13 (10), p.2432

2021

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Targeted arginine metabolomics: A rapid, simple UPLC-QToF-MSE based approach for assessing the involvement of arginine metabolism in human disease

Clinica chimica acta, 2015-07, Vol.447, p.59-65

2015

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Validation of a 3-h Sampling Interval to Assess Variability in Cytochrome P450 3A Phenotype and the Impact of Induction and Mechanism-Based Inhibition Using Midazolam as a Probe Substrate

Frontiers in pharmacology, 2019-09, Vol.10, p.1120-1120

2019

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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

Pharmaceutics, 2021-04, Vol.13 (5), p.601

2021

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Understanding the Risk of Drug Interactions Between Ritonavir-Containing COVID-19 Therapies and Small-Molecule Kinase Inhibitors in Patients With Cancer

JCO precision oncology, 2023-02, Vol.7, p.e2200538

2023

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Effect of early adverse events on response and survival outcomes of advanced melanoma patients treated with vemurafenib or vemurafenib plus cobimetinib: A pooled analysis of clinical trial data

Pigment cell and melanoma research, 2019-07, Vol.32 (4), p.576-583

2019

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Therapeutic drug monitoring of oral targeted antineoplastic drugs

Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides

Perspectives on Model‐Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations

Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure

Use of Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Axitinib Exposure: A Fresh Approach to Precision Dosing in Oncology

Evaluation of modafinil as a perpetrator of metabolic drug–drug interactions using a model informed cocktail reaction phenotyping trial protocol

Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries

Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years

Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges

Kinase inhibitor pharmacokinetics: comprehensive summary and roadmap for addressing inter-individual variability in exposure

Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity

Combining Therapeutic Drug Monitoring and Pharmacokinetic Modelling Deconvolutes Physiological and Environmental Sources of Variability in Clozapine Exposure

Plasma concentration guided dosing of drugs used for the treatment of childhood leukaemias: protocol for a systematic review

Cost-effectiveness of oral anticancer drugs and associated individualised dosing approaches in patients with cancer: protocol for a systematic review

A novel approach for the simultaneous quantification of 18 small molecule kinase inhibitors in human plasma: A platform for optimised KI dosing

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs

Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies

Physiologically-based pharmacokinetic modeling as an approach to evaluate the effect of covariates and drug-drug interactions on variability in epidermal growth factor receptor kinase inhibitor exposure

Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups

Targeted arginine metabolomics: A rapid, simple UPLC-QToF-MSE based approach for assessing the involvement of arginine metabolism in human disease

Validation of a 3-h Sampling Interval to Assess Variability in Cytochrome P450 3A Phenotype and the Impact of Induction and Mechanism-Based Inhibition Using Midazolam as a Probe Substrate

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

Understanding the Risk of Drug Interactions Between Ritonavir-Containing COVID-19 Therapies and Small-Molecule Kinase Inhibitors in Patients With Cancer

Effect of early adverse events on response and survival outcomes of advanced melanoma patients treated with vemurafenib or vemurafenib plus cobimetinib: A pooled analysis of clinical trial data

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