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Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

Blood, 2009-04, Vol.113 (18), p.4403-4413

2009

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The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo

Blood, 2010-11, Vol.116 (22), p.4578-4587

2010

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Safety and efficacy of abexinostat, a pan-histone deacetylase inhibitor, in non-Hodgkin lymphoma and chronic lymphocytic leukemia: results of a phase II study

Haematologica (Roma), 2017-05, Vol.102 (5), p.903-909

2017

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Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.18022-18027

2009

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Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines

Cell death & disease, 2024-04, Vol.15 (4), p.266-266, Article 266

2024

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Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.18078-18083

2014

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Phase IA/II, multicentre, open‐label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non‐Hodgkin or Hodgkin lymphoma

British journal of haematology, 2014-01, Vol.164 (2), p.258-265

2014

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Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia

British journal of haematology, 2013-08, Vol.162 (3), p.360-370

2013

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Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia

British journal of haematology, 2014-07, Vol.166 (1), p.12-22

2014

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Computational modeling of DLBCL predicts response to BH3-mimetics

NPJ systems biology and applications, 2023-06, Vol.9 (1), p.23-23, Article 23

2023

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Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

Blood, 2009-09, Vol.114 (11), p.2273-2279

2009

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ABT‐199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets

British journal of haematology, 2013-10, Vol.163 (1), p.139-142

2013

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Monitoring of molecular responses to tirabrutinib in a cohort of exceptional responders with relapsed/refractory mantle cell lymphoma

EJHaem, 2024-08, Vol.5 (4), p.896-899

2024

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Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: rare clinical curios or potent genetic drivers?

Blood, 2010-02, Vol.115 (8), p.1490-1499

2010

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Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells

Haematologica (Roma), 2010-09, Vol.95 (9), p.1510-1518

2010

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Diminished Sensitivity of Chronic Lymphocytic Leukemia Cells to ABT-737 and ABT-263 Due to Albumin Binding in Blood

Clinical cancer research, 2010-08, Vol.16 (16), p.4217-4225

2010

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Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies

Blood, 2010-08, Vol.116 (8), p.1317-1320

2010

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High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma

British journal of haematology, 2012-09, Vol.158 (6), p.712-726

2012

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Defining the prognosis of early stage chronic lymphocytic leukaemia patients

British journal of haematology, 2012-02, Vol.156 (4), p.499-507

2012

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Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non–high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol

Blood, 2010-07, Vol.115 (26), p.5393-5397

2010

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Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma

Leukemia, 2021-07, Vol.35 (7), p.2108-2113

2021

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Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo

Safety and efficacy of abexinostat, a pan-histone deacetylase inhibitor, in non-Hodgkin lymphoma and chronic lymphocytic leukemia: results of a phase II study

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines

Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

Phase IA/II, multicentre, open‐label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non‐Hodgkin or Hodgkin lymphoma

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia

Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia

Computational modeling of DLBCL predicts response to BH3-mimetics

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

ABT‐199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets

Monitoring of molecular responses to tirabrutinib in a cohort of exceptional responders with relapsed/refractory mantle cell lymphoma

Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: rare clinical curios or potent genetic drivers?

Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells

Diminished Sensitivity of Chronic Lymphocytic Leukemia Cells to ABT-737 and ABT-263 Due to Albumin Binding in Blood

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies

High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma

Defining the prognosis of early stage chronic lymphocytic leukaemia patients

Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non–high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

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