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A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges
Journal of Immunology Research, 2018-01, Vol.2018, p.8521060-15
2018
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Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus
Molecular therapy. Methods & clinical development, 2020-06, Vol.17 (C), p.810-821
2020
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Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses
PloS one, 2015-09, Vol.10 (9), p.e0137786-e0137786
2015
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A DNA Vaccine for Venezuelan Equine Encephalitis Virus Delivered by Intramuscular Electroporation Elicits High Levels of Neutralizing Antibodies in Multiple Animal Models and Provides Protective Immunity to Mice and Nonhuman Primates
Clinical and Vaccine Immunology, 2011-05, Vol.18 (5), p.707-716
2011
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A Phase 1 clinical trial of a DNA vaccine for Venezuelan equine encephalitis delivered by intramuscular or intradermal electroporation
Vaccine, 2016-06, Vol.34 (31), p.3607-3612
2016
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Current strategic thinking for the development of a trivalent alphavirus vaccine for human use
The American journal of tropical medicine and hygiene, 2014-09, Vol.91 (3), p.442-450
2014
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An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice
Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2824-2836
2017
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Epitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice
Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2883-2893
2017
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Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding
Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2953-2966
2017
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Filoviruses: Scientific Gaps and Prototype Pathogen Recommendation
The Journal of infectious diseases, 2023-10, Vol.228 (Supplement_6), p.S446-S459
2023
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A multiagent filovirus DNA vaccine delivered by intramuscular electroporation completely protects mice from ebola and Marburg virus challenge
Human vaccines & immunotherapeutics, 2012-11, Vol.8 (11), p.1595-1594
2012
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Self-Amplifying RNA Vaccines for Venezuelan Equine Encephalitis Virus Induce Robust Protective Immunogenicity in Mice
Molecular therapy, 2019-04, Vol.27 (4), p.850-865
2019
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Directed molecular evolution improves the immunogenicity and protective efficacy of a Venezuelan equine encephalitis virus DNA vaccine
Vaccine, 2009-06, Vol.27 (31), p.4152-4160
2009
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The Genetic Adjuvants Interleukin-12 and Granulocyte-Macrophage Colony Stimulating Factor Enhance the Immunogenicity of an Ebola Virus Deoxyribonucleic Acid Vaccine in Mice
The Journal of infectious diseases, 2018-11, Vol.218 (suppl_5), p.S519-S527
2018
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Comparison of Aerosol- and Percutaneous-acquired Venezuelan Equine Encephalitis in Humans and Nonhuman Primates for Suitability in Predicting Clinical Efficacy under the Animal Rule
Comparative medicine, 2018-10, Vol.68 (5), p.380-395
2018
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The genetic adjuvant IL-12 enhances the protective efficacy of a DNA vaccine for Venezuelan equine encephalitis virus delivered by intramuscular injection in mice
Antiviral research, 2018-11, Vol.159, p.113-121
2018
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Development of a bead-based immunoassay using virus-like particles for detection of alphaviral humoral response
Journal of virological methods, 2019-08, Vol.270, p.12-17
2019
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Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges
Human vaccines & immunotherapeutics, 2015-08, Vol.11 (8), p.1991-2004
2015
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Immunogenicity and protective efficacy of a DNA vaccine against Venezuelan equine encephalitis virus aerosol challenge in nonhuman primates
Vaccine, 2010-10, Vol.28 (46), p.7345-7350
2010
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DNA vaccines for biodefense
Expert review of vaccines, 2009-12, Vol.8 (12), p.1739-1754
2009
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Nonhuman primate models of encephalitic alphavirus infection: historical review and future perspectives
Current opinion in virology, 2012-06, Vol.2 (3), p.363-367
2012
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Novel plant-derived recombinant human interferons with broad spectrum antiviral activity
Antiviral research, 2011-12, Vol.92 (3), p.461-469
2011
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Probing the importance of tRNA anticodon: human immunodeficiency virus type 1 (HIV-1) RNA genome complementarity with an HIV-1 that selects tRNA(Glu) for replication
Journal of virology, 2003-08, Vol.77 (16), p.8756-8764
2003
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Interactions Between a Minimal Protein Serine/Threonine Phosphatase and Its Phosphopeptide Substrate Sequence
The Journal of biological chemistry, 1996-10, Vol.271 (40), p.24401-24407
1996
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HIV type 1 that select tRNA(His) or tRNA(Lys1,2) as primers for reverse transcription exhibit different infectivities in peripheral blood mononuclear cells
AIDS research and human retroviruses, 2004-04, Vol.20 (4), p.373-381
2004
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