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Mathematical modeling of postmenopausal osteoporosis and its treatment by the anti-catabolic drug denosumab

International journal for numerical methods in biomedical engineering, 2014-01, Vol.30 (1), p.1-27

2014

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Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

Cell, 1998-04, Vol.93 (2), p.165-176

1998

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Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

Cell, 1997-04, Vol.89 (2), p.309-319

1997

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The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption

Journal of bone and mineral research, 2000-01, Vol.15 (1), p.2-12

2000

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Nature (London), 1999-01, Vol.397 (6717), p.315-323

1999

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Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

Bone (New York, N.Y.), 1999-09, Vol.25 (3), p.255-259

1999

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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Genes & development, 1998-05, Vol.12 (9), p.1260-1268

1998

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Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis

Cancer research (Chicago, Ill.), 2001-06, Vol.61 (11), p.4432-4436

2001

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Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds

Acta biomaterialia, 2012-11, Vol.8 (11), p.4162-4172

2012

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Systemic Administration of Acidic Fibroblast Growth Factor (FGF‐1) Prevents Bone Loss and Increases New Bone Formation in Ovariectomized Rats

Journal of bone and mineral research, 1999-06, Vol.14 (6), p.953-959

1999

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Unique microstructural design of ceramic scaffolds for bone regeneration under load

Acta biomaterialia, 2013-06, Vol.9 (6), p.7014-7024

2013

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Combined treatment with PTH (1–34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats

Bone (New York, N.Y.), 2005-07, Vol.37 (1), p.87-95

2005

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A Single‐Dose Placebo‐Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Journal of bone and mineral research, 2004-07, Vol.19 (7), p.1059-1066

2004

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Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy

Cancer research (Chicago, Ill.), 2000-02, Vol.60 (4), p.783-787

2000

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Calcification in Atherosclerosis: Bone Biology and Chronic Inflammation at the Arterial Crossroads

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11201-11206

2003

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RANK ligand

The international journal of biochemistry & cell biology, 2007, Vol.39 (6), p.1077-1081

2007

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E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model

Cancer research (Chicago, Ill.), 1996-09, Vol.56 (17), p.4063-4070

1996

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The Effect of a Single Dose of Osteoprotegerin in Postmenopausal Women

Journal of bone and mineral research, 2001-02, Vol.16 (2), p.348-360

2001

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Osteoprotegerin mitigates tail suspension-induced osteopenia

Bone (New York, N.Y.), 2000-05, Vol.26 (5), p.443-449

2000

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TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

Genes & development, 1999-04, Vol.13 (8), p.1015-1024

1999

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The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft

Clinical & experimental metastasis, 2004-01, Vol.21 (5), p.381-387

2004

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Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts

Calcified tissue international, 1997-03, Vol.60 (3), p.283-290

1997

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Tumor Necrosis Factor Receptor Family Member RANK Mediates Osteoclast Differentiation and Activation Induced by Osteoprotegerin Ligand

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (7), p.3540-3545

1999

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RANK Is the Intrinsic Hematopoietic Cell Surface Receptor That Controls Osteoclastogenesis and Regulation of Bone Mass and Calcium Metabolism

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1566-1571

2000

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Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

Blood, 2001-12, Vol.98 (13), p.3534-3540

2001

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Mathematical modeling of postmenopausal osteoporosis and its treatment by the anti-catabolic drug denosumab

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis

Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds

Systemic Administration of Acidic Fibroblast Growth Factor (FGF‐1) Prevents Bone Loss and Increases New Bone Formation in Ovariectomized Rats

Unique microstructural design of ceramic scaffolds for bone regeneration under load

Combined treatment with PTH (1–34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats

A Single‐Dose Placebo‐Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy

Calcification in Atherosclerosis: Bone Biology and Chronic Inflammation at the Arterial Crossroads

RANK ligand

E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model

The Effect of a Single Dose of Osteoprotegerin in Postmenopausal Women

Osteoprotegerin mitigates tail suspension-induced osteopenia

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft

Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts

Tumor Necrosis Factor Receptor Family Member RANK Mediates Osteoclast Differentiation and Activation Induced by Osteoprotegerin Ligand

RANK Is the Intrinsic Hematopoietic Cell Surface Receptor That Controls Osteoclastogenesis and Regulation of Bone Mass and Calcium Metabolism

Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

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