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Quinazolin‐4(3H)‐one‐Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

Chemistry & biodiversity, 2019-04, Vol.16 (4), p.e1800502-n/a

2019

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Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons

Molecules (Basel, Switzerland), 2020-01, Vol.25 (2), p.324

2020

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Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

European journal of medicinal chemistry, 2013-12, Vol.70, p.477-486

2013

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New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2013-12, Vol.9 (8), p.1051-1057

2013

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Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety

Molecules (Basel, Switzerland), 2019-11, Vol.24 (21), p.4000

2019

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Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors

Bioorganic & medicinal chemistry letters, 2024-08, Vol.108, p.129796-129796, Article 129796

2024

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Synthesis and evaluation of biological activities of a series of (6-substituted benzothiazol-2-yl)acrylamides

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2011-11, Vol.7 (6), p.727-731

2011

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Development of Activity Rules and Chemical Fragment Design for In Silico Discovery of AChE and BACE1 Dual Inhibitors against Alzheimer's Disease

Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3588

2023

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Exploration of Some Thiazolidine-2,4-dione and 2-Oxoindoline Derivatives Incorporating 3,4,5-Trimethoxybenzyl Moiety as Novel Anticancer Agents

Letters in drug design & discovery, 2018-04, Vol.15 (4), p.375-387

2018

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Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents

Bioorganic & medicinal chemistry letters, 2020-11, Vol.30 (22), p.127537-127537, Article 127537

2020

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An Improved Procedure for the Synthesis of Amantadine Hydrochloride

Organic preparations and procedures international, 2022-05, Vol.54 (3), p.236-241

2022

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Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents

Bioorganic chemistry, 2018-02, Vol.76, p.258-267

2018

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Simple and Economical Process for Producing Amantadine Hydrochloride

ACS omega, 2022-02, Vol.7 (6), p.4787-4790

2022

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Synthesis and biological evaluation of a series of 2-(substitutedphenyl)benzothiazoles

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2011-03, Vol.7 (2), p.127-134

2011

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Novel 2-oxoindoline-based hydroxamic acids: synthesis, cytotoxicity, and inhibition of histone deacetylation

Tetrahedron letters, 2015-11, Vol.56 (46), p.6425-6429

2015

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Quinazoline‐Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

Chemistry & biodiversity, 2018-06, Vol.15 (6), p.e1800027-n/a

2018

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Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

Journal of enzyme inhibition and medicinal chemistry, 2014-10, Vol.29 (5), p.611-618

2014

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2-Aryl- and 2-amido-benzothiazoles as multifunctional vasodilators on rat artery preparations

European journal of pharmacology, 2013-08, Vol.714 (1-3), p.178-187

2013

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Exploration of some indole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

Chemical papers, 2017-09, Vol.71 (9), p.1759-1769

2017

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Exploration of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides as histone deacetylase inhibitors and antitumor agents

Arabian journal of chemistry, 2017-05, Vol.10 (4), p.465-472

2017

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5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2015-01, Vol.11 (3), p.296-304

2015

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Synthesis and Biological Evaluation of A Series of (Benzo[d]thiazol-2-yl)cyclohexanecarboxamides and (Benzo[d]thiazol-2-yl)cyclohexanecarbothioamides

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2010-05, Vol.6 (3), p.159-164

2010

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Harmonizing QSAR Machine Learning‐Based Models and Docking Approaches for Identifying Novel Histone Deacetylase 2 Inhibitors

ChemistrySelect (Weinheim), 2024-10, Vol.9 (40), p.n/a

2024

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Exploration of novel 5′(7′)-substituted-2

Arabian journal of chemistry, 2017-05, Vol.10 (4), p.465-472

2017

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Synthesis and bioevaluation of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety

Medicinal chemistry research, 2015-11, Vol.24 (11), p.3803-3812

2015

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Quinazolin‐4(3H)‐one‐Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents

Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety

Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors

Synthesis and evaluation of biological activities of a series of (6-substituted benzothiazol-2-yl)acrylamides

Development of Activity Rules and Chemical Fragment Design for In Silico Discovery of AChE and BACE1 Dual Inhibitors against Alzheimer's Disease

Exploration of Some Thiazolidine-2,4-dione and 2-Oxoindoline Derivatives Incorporating 3,4,5-Trimethoxybenzyl Moiety as Novel Anticancer Agents

Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents

An Improved Procedure for the Synthesis of Amantadine Hydrochloride

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents

Simple and Economical Process for Producing Amantadine Hydrochloride

Synthesis and biological evaluation of a series of 2-(substitutedphenyl)benzothiazoles

Novel 2-oxoindoline-based hydroxamic acids: synthesis, cytotoxicity, and inhibition of histone deacetylation

Quinazoline‐Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

2-Aryl- and 2-amido-benzothiazoles as multifunctional vasodilators on rat artery preparations

Exploration of some indole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

Exploration of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides as histone deacetylase inhibitors and antitumor agents

5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study

Synthesis and Biological Evaluation of A Series of (Benzo[d]thiazol-2-yl)cyclohexanecarboxamides and (Benzo[d]thiazol-2-yl)cyclohexanecarbothioamides

Harmonizing QSAR Machine Learning‐Based Models and Docking Approaches for Identifying Novel Histone Deacetylase 2 Inhibitors

Exploration of novel 5′(7′)-substituted-2

Synthesis and bioevaluation of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety

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