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In Vivo Resistance to a Human Immunodeficiency Virus Type 1 Proteinase Inhibitor: Mutations, Kinetics, and Frequencies

The Journal of infectious diseases, 1996-06, Vol.173 (6), p.1379-1387

1996

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Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro

Antimicrobial Agents and Chemotherapy, 1996-06, Vol.40 (6), p.1467-1471

1996

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Antiviral properties of Ro 31-8959, an inhibitor of human immunodeficiency virus (HIV) proteinase

Antiviral research, 1991-12, Vol.16 (4), p.295-305

1991

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HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy

AIDS (London), 1998-09, Vol.12 (13), p.1611-1618

1998

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Reduced sensitivity to saquinavir: an update on genotyping from phase I/II trials

Antiviral research, 1996, Vol.29 (1), p.95-97

1996

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Correlation of response to treatment and HIV genotypic changes during Phase III trials with saquinavir and reverse transcriptase inhibitor combination therapy

AIDS (London), 1998-08, Vol.12 (12), p.1465-1474

1998

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Rational Design of Peptide-Based HIV Proteinase Inhibitors

Science (American Association for the Advancement of Science), 1990-04, Vol.248 (4953), p.358-361

1990

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In vitro anti-HIV and Cytotoxicological Evaluation of the Triple Combination: AZT and ddC with HIV Proteinase Inhibitor Saquinavir (Ro 31-8959)

Antiviral chemistry & chemotherapy, 1994-12, Vol.5 (6), p.380-386

1994

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Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959

Virology (New York, N.Y.), 1995-01, Vol.206 (1), p.527-534

1995

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In vitro Resistance to an Inhibitor of HIV Proteinase (Ro 31-8959) Relative to Inhibitors of Reverse Transcriptase (AZT and TIBO)

Antiviral chemistry & chemotherapy, 1993-12, Vol.4 (6), p.335-339

1993

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Synthesis and antiviral activity of monofluoro and difluoro analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1)

Journal of medicinal chemistry, 1990-08, Vol.33 (8), p.2137-2145

1990

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Antiviral Synergy between Inhibitors of HIV Proteinase and Reverse Transcriptase

Antiviral chemistry & chemotherapy, 1993-06, Vol.4 (3), p.161-166

1993

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HIV proteinase inhibitors

Biochemical Society transactions, 1992-05, Vol.20 (2), p.513-516

1992

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Effects of a Specific Inhibitor of HIV Proteinase (Ro 31-8959) on Virus Maturation in a Chronically Infected Promonocytic Cell Line (U1)

Antiviral chemistry & chemotherapy, 1991-06, Vol.2 (3), p.181-186

1991

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Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides

Journal of medicinal chemistry, 1989-02, Vol.32 (2), p.367-374

1989

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Herpes simplex virus depresses antibody production by affecting T-cell function

Nature (London), 1980-03, Vol.284 (5752), p.176-177

1980

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Emergence of Gentamicin-Resistant Klebsiella in a General Hospital

Antimicrobial Agents and Chemotherapy, 1977-02, Vol.11 (2), p.179-184

1977

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Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus

Journal of Virology, 1971-07, Vol.8 (1), p.56-61

1971

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Isolation and Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus, New Jersey Serotype

Journal of Virology, 1971-12, Vol.8 (6), p.836-841

1971

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Combined biochemical and serological typing of clinical isolates of Klebsiella

Applied microbiology, 1974-10, Vol.28 (4), p.534-539

1974

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Epidemiology of Pseudomonas aeruginosa infections investigated by pyocin typing

Canadian Medical Association journal, 1975-04, Vol.112 (7), p.837-843

1975

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Antiviral activity of 5′-PAA and 5′-PFA phosphate esters of 2′-deoxyuridines

Journal of antimicrobial chemotherapy, 1986-10, Vol.18 (Supplement-B), p.201-205

1986

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The Allocation of Specialties to Hospitals in a Health District

The Journal of the Operational Research Society, 1979-11, Vol.30 (11), p.953-964

1979

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Operational Research in the Health and Social Services

Journal of the Royal Statistical Society, Series a (General), 1978-01, Vol.141 (2), p.153-194

1978

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A comparative study of 63 strains of ECHO virus type 30

Archiv für die gesamte Virusforschung, 1968-03, Vol.25 (1), p.93-104

Duncan, I B

1968

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In Vivo Resistance to a Human Immunodeficiency Virus Type 1 Proteinase Inhibitor: Mutations, Kinetics, and Frequencies

Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro

Antiviral properties of Ro 31-8959, an inhibitor of human immunodeficiency virus (HIV) proteinase

HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy

Reduced sensitivity to saquinavir: an update on genotyping from phase I/II trials

Correlation of response to treatment and HIV genotypic changes during Phase III trials with saquinavir and reverse transcriptase inhibitor combination therapy

Rational Design of Peptide-Based HIV Proteinase Inhibitors

In vitro anti-HIV and Cytotoxicological Evaluation of the Triple Combination: AZT and ddC with HIV Proteinase Inhibitor Saquinavir (Ro 31-8959)

Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959

In vitro Resistance to an Inhibitor of HIV Proteinase (Ro 31-8959) Relative to Inhibitors of Reverse Transcriptase (AZT and TIBO)

Synthesis and antiviral activity of monofluoro and difluoro analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1)

Antiviral Synergy between Inhibitors of HIV Proteinase and Reverse Transcriptase

HIV proteinase inhibitors

Effects of a Specific Inhibitor of HIV Proteinase (Ro 31-8959) on Virus Maturation in a Chronically Infected Promonocytic Cell Line (U1)

Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides

Herpes simplex virus depresses antibody production by affecting T-cell function

Emergence of Gentamicin-Resistant Klebsiella in a General Hospital

Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus

Isolation and Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus, New Jersey Serotype

Combined biochemical and serological typing of clinical isolates of Klebsiella

Epidemiology of Pseudomonas aeruginosa infections investigated by pyocin typing

Antiviral activity of 5′-PAA and 5′-PFA phosphate esters of 2′-deoxyuridines

The Allocation of Specialties to Hospitals in a Health District

Operational Research in the Health and Social Services

A comparative study of 63 strains of ECHO virus type 30

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