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An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44425-44434

2012

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The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

The Journal of cell biology, 1997-06, Vol.137 (6), p.1445-1457

1997

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Structural Analysis of the α2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) Interaction

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29375-29381

2001

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Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease

International journal of alzheimer's disease, 2012, Vol.2012 (2012), p.1-10

2012

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An improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates

Journal of neuroscience methods, 2013-02, Vol.213 (1), p.14-21

2013

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Minimization of drug–drug interaction risk and candidate selection in a natural product-based class of gamma-secretase modulators

Bioorganic & medicinal chemistry letters, 2015-04, Vol.25 (7), p.1621-1626

2015

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Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models

Alzheimer's research & therapy, 2013-04, Vol.5 (2), p.19-19, Article 19

2013

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An improved cell-based method for determining the gamma-secretase enzyme activity against both Notch and APP substrates

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P296-P296

2012

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P2‐095: An improved cell‐based method for determining the gamma‐secretase enzyme activity against both Notch and APP substrates

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_8), p.P296-P296

2012

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Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29368-29374

2001

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Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

Biomarkers, 2012-09, Vol.17 (6), p.524-531

2012

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Satori gamma-secretase modulators are efficacious in wild-type rodents following either acute or steady-state dosing

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P104-P104

2012

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O1‐11‐01: Satori gamma‐secretase modulators are efficacious in wild‐type rodents following either acute or steady‐state dosing

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_3), p.P104-P104

2012

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Pharmacokinetic properties of a Satori gamma-secretase modulator, SPI-1865, in multiple animal model systems

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P705-P705

2012

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P4‐199: Pharmacokinetic properties of a Satori gamma‐secretase modulator, SPI‐1865, in multiple animal model systems

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_19), p.P705-P705

2012

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N-(6,7-Dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-d-aspartate receptor antagonists for the treatment of pain

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4599-4603

2007

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P3‐393: The effect of 5‐lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer‐like pathology

Alzheimer's & dementia, 2010-07, Vol.6 (4S_Part_18), p.S567-S568

2010

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The effect of 5-lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer-like pathology

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.S567-S568

2010

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Keratinocyte Collagenase-1 Expression Requires an Epidermal Growth Factor Receptor Autocrine Mechanism

The Journal of biological chemistry, 1999-04, Vol.274 (15), p.10372-10381

1999

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Structural Analysis of the Î±2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) Interaction

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29375

2001

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Serotonin regulation of interleukin-1 messenger RNA in rat uterine smooth muscle cells. Relationship to the production of interstitial collagenase

The Journal of biological chemistry, 1994-11, Vol.269 (47), p.29658-29664

1994

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Serotonin-dependent collagenase transcription in myometrial cells requires extended AP-1 site

Molecular and cellular endocrinology, 2000-12, Vol.170 (1), p.41-56

2000

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Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the Î±2Î²1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29368

2001

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Role of interleukin-1 and interleukin-6 in the serotonin-mediated production of interstitial collagenase by myometrial smooth muscle cells

Dumin, Jo Ann

1996

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An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition

The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

Structural Analysis of the α2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) Interaction

Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease

An improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates

Minimization of drug–drug interaction risk and candidate selection in a natural product-based class of gamma-secretase modulators

Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models

An improved cell-based method for determining the gamma-secretase enzyme activity against both Notch and APP substrates

P2‐095: An improved cell‐based method for determining the gamma‐secretase enzyme activity against both Notch and APP substrates

Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen

Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

Satori gamma-secretase modulators are efficacious in wild-type rodents following either acute or steady-state dosing

O1‐11‐01: Satori gamma‐secretase modulators are efficacious in wild‐type rodents following either acute or steady‐state dosing

Pharmacokinetic properties of a Satori gamma-secretase modulator, SPI-1865, in multiple animal model systems

P4‐199: Pharmacokinetic properties of a Satori gamma‐secretase modulator, SPI‐1865, in multiple animal model systems

N-(6,7-Dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-d-aspartate receptor antagonists for the treatment of pain

P3‐393: The effect of 5‐lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer‐like pathology

The effect of 5-lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer-like pathology

Keratinocyte Collagenase-1 Expression Requires an Epidermal Growth Factor Receptor Autocrine Mechanism

Structural Analysis of the Î±2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) Interaction

Serotonin regulation of interleukin-1 messenger RNA in rat uterine smooth muscle cells. Relationship to the production of interstitial collagenase

Serotonin-dependent collagenase transcription in myometrial cells requires extended AP-1 site

Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the Î±2Î²1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen

Role of interleukin-1 and interleukin-6 in the serotonin-mediated production of interstitial collagenase by myometrial smooth muscle cells

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