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C‑Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive Action

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2431-2440

2015

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Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current INa by Lamotrigine; A Potential for Acquired Arrythmias

Pharmaceuticals (Basel, Switzerland), 2022-09, Vol.15 (10), p.1208

2022

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The neuronal potassium current IA is a potential target for pain during chronic inflammation

Physiological reports, 2021-08, Vol.9 (16), p.n/a

2021

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Comparison of K+ currents in cardiac Purkinje cells isolated from rabbit and dog

Journal of molecular and cellular cardiology, 2007-02, Vol.42 (2), p.378-389

2007

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Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations

Circulation (New York, N.Y.), 2004-11, Vol.110 (19), p.3023-3027

2004

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Ionic Mechanisms Responsible for the Electrocardiographic Phenotype of the Brugada Syndrome Are Temperature Dependent

Circulation research, 1999-10, Vol.85 (9), p.803-809

1999

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Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart

The Journal of physiology, 2005-05, Vol.564 (3), p.683-696

2005

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A Molecular Link between the Sudden Infant Death Syndrome and the Long-QT Syndrome

The New England journal of medicine, 2000-07, Vol.343 (4), p.262-267

2000

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Abstract 14308: Lamotrigine Inhibits the Inward Fast Sodium Current (I Na ) in Epileptic Rat Cardiomyocytes

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Lidocaine-Induced Brugada Syndrome Phenotype Linked to a Novel Double Mutation in the Cardiac Sodium Channel

Circulation research, 2008-08, Vol.103 (4), p.396-404

2008

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Molecular basis of species-specific expression of repolarizing K+ currents in the heart

American journal of physiology. Heart and circulatory physiology, 2003-10, Vol.285 (4), p.H1641-H1649

2003

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HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

Circulation (New York, N.Y.), 1996-08, Vol.94 (4), p.817-823

1996

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Identification of Two Domains Involved in the Assembly of Transient Receptor Potential Canonical Channels

The Journal of biological chemistry, 2006-10, Vol.281 (41), p.30356-30364

2006

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Multiple mechanisms of Na+ channel-linked long-QT syndrome

Circulation research, 1996-05, Vol.78 (5), p.916-924

1996

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Genetic and biophysical basis for bupivacaine-induced ST segment elevation and VT/VF. Anesthesia unmasked Brugada syndrome

Heart rhythm, 2006-09, Vol.3 (9), p.1074-1078

2006

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Blockade of HERG and Kv1.5 by ketoconazole

The Journal of pharmacology and experimental therapeutics, 1998-08, Vol.286 (2), p.727

1998

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Apelin Compared With Dobutamine Exerts Cardioprotection and Extends Survival in a Rat Model of Endotoxin-Induced Myocardial Dysfunction

Critical care medicine, 2017-04, Vol.45 (4), p.e391-e398

2017

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Abstract 14243: The Apelin Mimetic Peptide (2Nal) Partially Inhibits the Transient Outward Potassium Current (Ito) in Rat Cardiomyocytes; a Potential Pharmacological Agent Against Brugada Syndrome

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock

Critical care medicine, 2017-11, Vol.45 (11), p.e1139-e1148

2017

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Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.2962-2972

2016

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Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current I[sub.Na] by Lamotrigine; A Potential for Acquired Arrythmias

Pharmaceuticals (Basel, Switzerland), 2022-09, Vol.15 (10)

2022

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Apelin-13 Regulates Vasopressin-Induced Aquaporin-2 Expression and Trafficking in Kidney Collecting Duct Cells

Cellular physiology and biochemistry, 2019-01, Vol.53 (4), p.687-700

2019

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Sudden death associated with short-QT syndrome linked to mutations in HERG

Circulation (New York, N.Y.), 2004-01, Vol.109 (1), p.30-35

2004

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The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment

Pharmacological research, 2018-05, Vol.131, p.7-16

2018

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A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2266-2277

2018

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C‑Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive Action

Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current INa by Lamotrigine; A Potential for Acquired Arrythmias

The neuronal potassium current IA is a potential target for pain during chronic inflammation

Comparison of K+ currents in cardiac Purkinje cells isolated from rabbit and dog

Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations

Ionic Mechanisms Responsible for the Electrocardiographic Phenotype of the Brugada Syndrome Are Temperature Dependent

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart

A Molecular Link between the Sudden Infant Death Syndrome and the Long-QT Syndrome

Abstract 14308: Lamotrigine Inhibits the Inward Fast Sodium Current (I Na ) in Epileptic Rat Cardiomyocytes

Lidocaine-Induced Brugada Syndrome Phenotype Linked to a Novel Double Mutation in the Cardiac Sodium Channel

Molecular basis of species-specific expression of repolarizing K+ currents in the heart

HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

Identification of Two Domains Involved in the Assembly of Transient Receptor Potential Canonical Channels

Multiple mechanisms of Na+ channel-linked long-QT syndrome

Genetic and biophysical basis for bupivacaine-induced ST segment elevation and VT/VF. Anesthesia unmasked Brugada syndrome

Blockade of HERG and Kv1.5 by ketoconazole

Apelin Compared With Dobutamine Exerts Cardioprotection and Extends Survival in a Rat Model of Endotoxin-Induced Myocardial Dysfunction

Abstract 14243: The Apelin Mimetic Peptide (2Nal) Partially Inhibits the Transient Outward Potassium Current (Ito) in Rat Cardiomyocytes; a Potential Pharmacological Agent Against Brugada Syndrome

ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock

Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current I[sub.Na] by Lamotrigine; A Potential for Acquired Arrythmias

Apelin-13 Regulates Vasopressin-Induced Aquaporin-2 Expression and Trafficking in Kidney Collecting Duct Cells

Sudden death associated with short-QT syndrome linked to mutations in HERG

The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment

A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects

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