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Hsp70 and Antifibrillogenic Peptides Promote Degradation and Inhibit Intracellular Aggregation of Amyloidogenic Light Chains

The Journal of cell biology, 2001-02, Vol.152 (4), p.705-715

2001

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Inhibition of Amyloid Fiber Assembly by Both BiP and Its Target Peptide

Immunity (Cambridge, Mass.), 2000-10, Vol.13 (4), p.433-442

2000

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Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

Nature (London), 1994-08, Vol.370 (6488), p.373-375

1994

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A Single Amino Acid Substitution in the Variable Region of the Light Chain Specifically Blocks Immunoglobulin Secretion

Proceedings of the National Academy of Sciences - PNAS, 1990-10, Vol.87 (20), p.8135-8139

1990

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Ig light chains are secreted predominantly as monomers

The Journal of immunology (1950), 1996-10, Vol.157 (7), p.2969

1996

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Both the environment and somatic mutations govern the aggregation pathway of pathogenic immunoglobulin light chain

Journal of molecular biology, 2001-11, Vol.313 (5), p.1021-1034

2001

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The expression of membrane and secreted immunoglobulin during the in vitro differentiation of the murine B cell lymphoma CH12

The Journal of immunology (1950), 1987-11, Vol.139 (10), p.3527

1987

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Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies

Clinical cancer research, 2006-02, Vol.12 (4), p.1251-1259

2006

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Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in Vpre-B1-deficient mice

International immunology, 1999-03, Vol.11 (3), p.453-460

1999

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The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co‐expressed during B cell development

European journal of immunology, 1996-04, Vol.26 (4), p.906-913

1996

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Transcription stimulates recombination II. Generalized transduction of Escherichia coli by phages T1 and T4

Virology (New York, N.Y.), 1988-02, Vol.162 (2), p.471-477

1988

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Transcription stimulates recombination I. Specialized transduction of Escherichia coli by λtrp phages

Virology (New York, N.Y.), 1988-02, Vol.162 (2), p.466-470

1988

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Modeling and simulation of neutropenia to support dosing regimens for liposome-encapsulated paclitaxel easy-to-use (LEP- ETU)

Journal of clinical oncology, 2007-06, Vol.25 (18_suppl), p.13011-13011

2007

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Final results of a Phase I study of Liposome Entrapped Paclitaxel (LEP-ETU) in patients with advanced cancer

Journal of clinical oncology, 2005-06, Vol.23 (16_suppl), p.2048-2048

2005

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Final results of a phase I study of liposome encapsulated SN-38 (LE-SN38): Safety, pharmacogenomics, pharmacokinetics, and tumor response

Journal of clinical oncology, 2005-06, Vol.23 (16_suppl), p.2017-2017

2005

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Phase I study of LErafAON-ETU, an easy-to-use formulation of liiposome entrapped c-raf antisense oligonucleotide, in advanced cancer patients

Journal of clinical oncology, 2005-06, Vol.23 (16_suppl), p.3214-3214

2005

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Phase I study of liposome entrapped paclitaxel (LEP-ETU) in patients with advanced cancer

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.2110-2110

2004

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Phase I study of liposome entrapped paclitaxel (LEP-ETU) in patients with advanced cancer

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.2110-2110

2004

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Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.2501-2501

2004

Volltextzugriff (PDF)

Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.2501-2501

2004

Volltextzugriff (PDF)

Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in V sub(pre-B1)-deficient mice

International immunology, 1999-03, Vol.11 (3), p.453-460

1999

Volltextzugriff (PDF)

The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development

European journal of immunology, 1996-01, Vol.126 (4), p.906-913

1996

Volltextzugriff (PDF)

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2989-2994

2012

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A Pragmatic Cluster-Randomized Trial of a Standing Order Entry Intervention for Colony-Stimulating Factor Use Among Patients at Intermediate Risk for Febrile Neutropenia

Journal of clinical oncology, 2023-01, Vol.41 (3), p.590-598

2023

Volltextzugriff (PDF)

An Observational Study of Sepsis in Takeo Province Cambodia: An in-depth examination of pathogens causing severe infections

PLoS neglected tropical diseases, 2020-08, Vol.14 (8), p.e0008381-e0008381

2020

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Hsp70 and Antifibrillogenic Peptides Promote Degradation and Inhibit Intracellular Aggregation of Amyloidogenic Light Chains

Inhibition of Amyloid Fiber Assembly by Both BiP and Its Target Peptide

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

A Single Amino Acid Substitution in the Variable Region of the Light Chain Specifically Blocks Immunoglobulin Secretion

Ig light chains are secreted predominantly as monomers

Both the environment and somatic mutations govern the aggregation pathway of pathogenic immunoglobulin light chain

The expression of membrane and secreted immunoglobulin during the in vitro differentiation of the murine B cell lymphoma CH12

Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies

Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in Vpre-B1-deficient mice

The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co‐expressed during B cell development

Transcription stimulates recombination II. Generalized transduction of Escherichia coli by phages T1 and T4

Transcription stimulates recombination I. Specialized transduction of Escherichia coli by λtrp phages

Modeling and simulation of neutropenia to support dosing regimens for liposome-encapsulated paclitaxel easy-to-use (LEP- ETU)

Final results of a Phase I study of Liposome Entrapped Paclitaxel (LEP-ETU) in patients with advanced cancer

Final results of a phase I study of liposome encapsulated SN-38 (LE-SN38): Safety, pharmacogenomics, pharmacokinetics, and tumor response

Phase I study of LErafAON-ETU, an easy-to-use formulation of liiposome entrapped c-raf antisense oligonucleotide, in advanced cancer patients

Phase I study of liposome entrapped paclitaxel (LEP-ETU) in patients with advanced cancer

Phase I study of liposome entrapped paclitaxel (LEP-ETU) in patients with advanced cancer

Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients

Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients

Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in V sub(pre-B1)-deficient mice

The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

A Pragmatic Cluster-Randomized Trial of a Standing Order Entry Intervention for Colony-Stimulating Factor Use Among Patients at Intermediate Risk for Febrile Neutropenia

An Observational Study of Sepsis in Takeo Province Cambodia: An in-depth examination of pathogens causing severe infections

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