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Metabolic disposition studies on simvastatin, a cholesterol-lowering prodrug

Drug metabolism and disposition, 1990-03, Vol.18 (2), p.138

1990

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Effects of dose, sex, and age on the disposition of alendronate, a potent antiosteolytic bisphosphonate, in rats

Drug metabolism and disposition, 1992-07, Vol.20 (4), p.473

1992

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Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals

Drug metabolism and disposition, 1991-09, Vol.19 (5), p.926

1991

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The physiological disposition of lovastatin

Drug metabolism and disposition, 1989-03, Vol.17 (2), p.166

1989

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In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase

Drug metabolism and disposition, 1990-07, Vol.18 (4), p.476

1990

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Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human

Drug metabolism and disposition, 1993-11, Vol.21 (6), p.1003

1993

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Selective inhibitors of biosynthesis of aminergic neurotransmitters

Nature (London), 1978-08, Vol.274 (5674), p.906-908

1978

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Physiological Disposition of Hmg-Coa-Reductase Inhibitors

Drug metabolism reviews, 1990, Vol.22 (4), p.333-362

1990

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Kinetic studies on the competition between famotidine and cimetidine in rats. Evidence of multiple renal secretory systems for organic cations

Drug metabolism and disposition, 1988-01, Vol.16 (1), p.52

1988

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Differential renal handling of angiotensin-converting enzyme inhibitors enalaprilat and lisinopril in rats

Drug metabolism and disposition, 1988-05, Vol.16 (3), p.392

1988

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Biotransformation of lovastatin. II. In vitro metabolism by rat and mouse liver microsomes and involvement of cytochrome P-450 in dehydrogenation of lovastatin

Drug metabolism and disposition, 1990-03, Vol.18 (2), p.218

1990

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Dose-dependent pharmacokinetics of diflunisal in rats: dual effects of protein binding and metabolism

The Journal of pharmacology and experimental therapeutics, 1985-11, Vol.235 (2), p.402

1985

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Protein binding as a primary determinant of the clinical pharmacokinetic properties of non-steroidal anti-inflammatory drugs

Clinical pharmacokinetics, 1987-06, Vol.12 (6), p.402-432

1987

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Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats

The Journal of pharmacology and experimental therapeutics, 1987-09, Vol.242 (3), p.1013

1987

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Urinary excretion kinetics of famotidine in rats

Drug metabolism and disposition, 1987-03, Vol.15 (2), p.212

1987

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Possible mechanisms for reduced plasma clearance of diflunisal in rat experimental renal failure

The Journal of pharmacology and experimental therapeutics, 1986-09, Vol.238 (3), p.978

1986

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Kinetics of the tissue distributions of sulindac and metabolites. Relevance to sites and rates of bioactivation

Drug metabolism and disposition, 1980-07, Vol.8 (4), p.241

1980

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Effect of enterohepatic circulation on the pharmacokinetics of diflunisal in rats

Drug metabolism and disposition, 1985-05, Vol.13 (3), p.321

1985

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Dose-dependent pharmacokinetics of MK-417, a potent carbonic anhydrase inhibitor, in rabbits following single and multiple doses

Drug metabolism and disposition, 1990-11, Vol.18 (6), p.836

1990

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Identification of the biologically active form of sulindac

The Journal of pharmacology and experimental therapeutics, 1977-04, Vol.201 (1), p.8

1977

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Effect of uremia and anephric state on the pharmacokinetics of sulindac and its metabolites in rats. I. An application of pharmacokinetic model for reversible metabolism

Drug metabolism and disposition, 1985-09, Vol.13 (5), p.602

1985

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4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1,2,4-triazoles, new classes of xanthine oxidase inhibitors

Journal of medicinal chemistry, 1975-09, Vol.18 (9), p.895-900

1975

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Effect of uremia and anephric state on the pharmacokinetics of sulindac and its metabolites in rats. II. Differential effects on the biliary excretion

Drug metabolism and disposition, 1985-09, Vol.13 (5), p.608

1985

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Inhibition of histamine synthesis in vitro and in vivo by S-α-fluoromethylhistidine

Biochemical pharmacology, 1984-12, Vol.33 (24), p.4003-4009

1984

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The metabolism of indomethacin in man

The Journal of pharmacology and experimental therapeutics, 1972-06, Vol.181 (3), p.563

1972

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Metabolic disposition studies on simvastatin, a cholesterol-lowering prodrug

Effects of dose, sex, and age on the disposition of alendronate, a potent antiosteolytic bisphosphonate, in rats

Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals

The physiological disposition of lovastatin

In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase

Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human

Selective inhibitors of biosynthesis of aminergic neurotransmitters

Physiological Disposition of Hmg-Coa-Reductase Inhibitors

Kinetic studies on the competition between famotidine and cimetidine in rats. Evidence of multiple renal secretory systems for organic cations

Differential renal handling of angiotensin-converting enzyme inhibitors enalaprilat and lisinopril in rats

Biotransformation of lovastatin. II. In vitro metabolism by rat and mouse liver microsomes and involvement of cytochrome P-450 in dehydrogenation of lovastatin

Dose-dependent pharmacokinetics of diflunisal in rats: dual effects of protein binding and metabolism

Protein binding as a primary determinant of the clinical pharmacokinetic properties of non-steroidal anti-inflammatory drugs

Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats

Urinary excretion kinetics of famotidine in rats

Possible mechanisms for reduced plasma clearance of diflunisal in rat experimental renal failure

Kinetics of the tissue distributions of sulindac and metabolites. Relevance to sites and rates of bioactivation

Effect of enterohepatic circulation on the pharmacokinetics of diflunisal in rats

Dose-dependent pharmacokinetics of MK-417, a potent carbonic anhydrase inhibitor, in rabbits following single and multiple doses

Identification of the biologically active form of sulindac

Effect of uremia and anephric state on the pharmacokinetics of sulindac and its metabolites in rats. I. An application of pharmacokinetic model for reversible metabolism

4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1,2,4-triazoles, new classes of xanthine oxidase inhibitors

Effect of uremia and anephric state on the pharmacokinetics of sulindac and its metabolites in rats. II. Differential effects on the biliary excretion

Inhibition of histamine synthesis in vitro and in vivo by S-α-fluoromethylhistidine

The metabolism of indomethacin in man

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