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Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2017-11, Vol.61 (11)

2017

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Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2017-12, Vol.61 (12)

2017

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Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

The Lancet infectious diseases, 2015-02, Vol.15 (2), p.225-234

2015

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Use of Monte Carlo simulation and considerations for PK-PD targets to support antibacterial dose selection

Current opinion in pharmacology, 2017-10, Vol.36, p.107-113

2017

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In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2018-01, Vol.62 (1)

2018

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Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics against Isogenic Strains Expressing Single Beta-Lactamases

Antimicrobial agents and chemotherapy, 2020-05, Vol.64 (6)

2020

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Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7491-7507

2020

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Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2018-02, Vol.319 (8), p.788

2018

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Recycling of solar PV panels- product stewardship and regulatory approaches

Energy policy, 2021-02, Vol.149, p.112062, Article 112062

2021

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A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Nature communications, 2022-03, Vol.13 (1), p.1625-15, Article 1625

2022

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Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Infectious diseases and therapy, 2018-12, Vol.7 (4), p.439-455

2018

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Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3682-3692

2015

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Consequences of a Health System Not Knowing Which Patients Are Deceased

JAMA internal medicine, 2024-02, Vol.184 (2), p.213

2024

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Preventing suicide by young people requires integrative strategies

Medical journal of Australia, 2022-01, Vol.216 (1), p.55-55

2022

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Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Rat Pneumonia Model

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.6326-6332

2016

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Meropenem-RPX7009 Concentrations in Plasma, Epithelial Lining Fluid, and Alveolar Macrophages of Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2015-12, Vol.59 (12), p.7232-7239

2015

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Preventing suicide by young people requires integrative strategies

Medical journal of Australia, 2021-02, Vol.214 (3), p.125-126

2021

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Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the United States Committee on Antimicrobial Susceptibility Testing (USCAST)

Antimicrobial agents and chemotherapy, 2020-01, Vol.64 (2)

2020

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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Vaborbactam and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2018-04, Vol.62 (4)

2018

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Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

Journal of antimicrobial chemotherapy, 2005-05, Vol.55 (5), p.601-607

2005

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Activity of Meropenem-Vaborbactam in Mouse Models of Infection Due to KPC-Producing Carbapenem-Resistant Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2018-01, Vol.62 (1)

2018

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Background and Rationale for Revised Clinical and Laboratory Standards Institute Interpretive Criteria (Breakpoints) for Enterobacteriaceae and Pseudomonas aeruginosa: I. Cephalosporins and Aztreonam

Clinical infectious diseases, 2013-05, Vol.56 (9), p.1301-1309

2013

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Strain mapping of GaN substrates and epitaxial layers used for power electronic devices by synchrotron X-ray rocking curve topography

Journal of crystal growth, 2022-04, Vol.583 (C), p.126559, Article 126559

2022

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Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae

Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

Use of Monte Carlo simulation and considerations for PK-PD targets to support antibacterial dose selection

In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae

Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem

Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics against Isogenic Strains Expressing Single Beta-Lactamases

Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases

Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial

Recycling of solar PV panels- product stewardship and regulatory approaches

A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Consequences of a Health System Not Knowing Which Patients Are Deceased

Preventing suicide by young people requires integrative strategies

Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Rat Pneumonia Model

Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects

Meropenem-RPX7009 Concentrations in Plasma, Epithelial Lining Fluid, and Alveolar Macrophages of Healthy Adult Subjects

Preventing suicide by young people requires integrative strategies

Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the United States Committee on Antimicrobial Susceptibility Testing (USCAST)

Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Vaborbactam and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

Activity of Meropenem-Vaborbactam in Mouse Models of Infection Due to KPC-Producing Carbapenem-Resistant Enterobacteriaceae

Background and Rationale for Revised Clinical and Laboratory Standards Institute Interpretive Criteria (Breakpoints) for Enterobacteriaceae and Pseudomonas aeruginosa: I. Cephalosporins and Aztreonam

Strain mapping of GaN substrates and epitaxial layers used for power electronic devices by synchrotron X-ray rocking curve topography

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