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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

Cancer cell, 2019-11, Vol.36 (5), p.545-558.e7

2019

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Design of a small molecule against an oncogenic noncoding RNA

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (21), p.5898-5903

2016

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Coordination games in cancer

PloS one, 2022-01, Vol.17 (1), p.e0261578

2022

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Autophagy is inhibited by ubiquitin ligase activity in the nervous system

Nature communications, 2019-11, Vol.10 (1), p.5017-17, Article 5017

2019

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An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level

PLoS computational biology, 2024-02, Vol.20 (2), p.e1011873-e1011873

2024

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Metabolism considerations for kinase inhibitors in cancer treatment

Expert opinion on drug metabolism & toxicology, 2010-10, Vol.6 (10), p.1175-1193

2010

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Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas

Haematologica (Roma), 2022-05, Vol.107 (5), p.1119-1130

2022

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Antiproliferation activity of a small molecule repressor of liver receptor homolog 1

Molecular pharmacology, 2015-02, Vol.87 (2), p.296-304

2015

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Quantification of healthy follicles in the neonatal and adult mouse ovary: evidence for maintenance of primordial follicle supply

Reproduction (Cambridge, England), 2006-07, Vol.132 (1), p.95-109

2006

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Perfectionism and motivation in sport : the mediating role of mental toughness

South African Journal of Science, 2019-01, Vol.115 (1-2), p.57-63

2019

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The promise and current status of CDK12/13 inhibition for the treatment of cancer

Future medicinal chemistry, 2021-01, Vol.13 (2), p.117-141

2021

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Modelling of the energy absorption by polymer composites upon ballistic impact

Composites science and technology, 2000-08, Vol.60 (14), p.2631-2642

2000

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Structure-independent machine-learning predictions of the CDK12 interactome

Biophysical journal, 2024-09, Vol.123 (17), p.2910-2920

2024

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Barriers to seeking treatment for women with persistent or recurrent symptoms in urogynaecology

BJOG : an international journal of obstetrics and gynaecology, 2009-04, Vol.116 (5), p.726-730

2009

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Uterus conserving prolapse surgery—what is the chance of missing a malignancy?

International Urogynecology Journal, 2010-07, Vol.21 (7), p.819-821

2010

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Polypropylene hybrid composites reinforced with long glass fibres and particulate filler

Composites science and technology, 2005-02, Vol.65 (2), p.257-267

2005

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In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1

Molecular cancer therapeutics, 2007-02, Vol.6 (2), p.450-459

2007

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The risk and severity of developing symptomatic palpitations when prescribed mirabegron for overactive bladder

European journal of obstetrics & gynecology and reproductive biology, 2015-04, Vol.187, p.60-63

2015

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Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction

Journal of medicinal chemistry, 2021-08, Vol.64 (16), p.12109-12131

2021

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A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1

Nature (London), 2011-08, Vol.477 (7364), p.349-353

2011

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The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105501-105501, Article 105501

2024

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Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ

Journal of medicinal chemistry, 2023-06, Vol.66 (11), p.7162-7178

2023

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Tolerability and efficacy of duloxetine in a nontrial situation

BJOG : an international journal of obstetrics and gynaecology, 2007-05, Vol.114 (5), p.543-547

2007

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The effect of hydrostatic pressure on the mechanical properties of glass fibre/epoxy unidirectional composites

Composites. Part A, Applied science and manufacturing, 2005, Vol.36 (2), p.279-289

2005

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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

Design of a small molecule against an oncogenic noncoding RNA

Coordination games in cancer

Autophagy is inhibited by ubiquitin ligase activity in the nervous system

An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level

Metabolism considerations for kinase inhibitors in cancer treatment

Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas

Antiproliferation activity of a small molecule repressor of liver receptor homolog 1

Quantification of healthy follicles in the neonatal and adult mouse ovary: evidence for maintenance of primordial follicle supply

Perfectionism and motivation in sport : the mediating role of mental toughness

The promise and current status of CDK12/13 inhibition for the treatment of cancer

Modelling of the energy absorption by polymer composites upon ballistic impact

Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase

Structure-independent machine-learning predictions of the CDK12 interactome

Barriers to seeking treatment for women with persistent or recurrent symptoms in urogynaecology

Uterus conserving prolapse surgery—what is the chance of missing a malignancy?

Polypropylene hybrid composites reinforced with long glass fibres and particulate filler

In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1

The risk and severity of developing symptomatic palpitations when prescribed mirabegron for overactive bladder

Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1

The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation

Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ

Tolerability and efficacy of duloxetine in a nontrial situation

The effect of hydrostatic pressure on the mechanical properties of glass fibre/epoxy unidirectional composites

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