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Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Journal of thrombosis and haemostasis, 2008-10, Vol.6 (10), p.1697-1706

2008

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Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Journal of thrombosis and haemostasis, 2008-10, Vol.6 (10), p.1697-1706

2008

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Experimental Proof for the Structure of a Thrombin-Inhibiting Heparin Molecule

Chemistry : a European journal, 2001-02, Vol.7 (4), p.858-873

2001

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The structure of synthetic oligosaccharides in relation to factor IXa inhibition

Thrombosis and haemostasis, 2002-09, Vol.88 (3), p.432

2002

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Synthesis of thrombin-inhibiting heparin mimetics without side effects

Nature (London), 1999-04, Vol.398 (6726), p.417-422

1999

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Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

Journal of thrombosis and haemostasis, 2003-09, Vol.1 (9), p.2008-2013

2003

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SR123781A, a synthetic heparin mimetic

Thrombosis and haemostasis, 2001-05, Vol.85 (5), p.852

2001

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The Synthetic Pentasaccharide Fondaparinux: First in the Class of Antithrombotic Agents that Selectively Inhibit Coagulation Factor Xa

Seminars in thrombosis and hemostasis, 2002-08, Vol.28 (4), p.393-402

2002

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A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity

Bioorganic & medicinal chemistry letters, 1997-08, Vol.7 (15), p.2067-2070

1997

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A new, highly potent, heparin-like pentasaccharide fragment containing a glucose residue instead of a glucosamine

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (2), p.95-98

1991

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A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers

Bioorganic & medicinal chemistry, 1999-08, Vol.7 (8), p.1567-1580

1999

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First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin

Angewandte Chemie (International ed.), 1998-11, Vol.37 (21), p.3009-3014

1998

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p-Anisyl ethers in carbohydrate chemistry: Selective protection of the primary alcohol function

Tetrahedron letters, 1988, Vol.29 (12), p.1389-1390

1988

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The first total synthesis of the antithrombin III binding site of porcine mucosa heparin

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (2), p.99-102

1991

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Synthesis and Pharmacological Properties of a Close Analogue of an Antithrombotic Pentasaccharide (SR 90107A/ORG 31540)

Journal of medicinal chemistry, 1997-05, Vol.40 (11), p.1600-1607

1997

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l-Iduronic acid derivatives as glycosyl donors

Carbohydrate research, 1996-02, Vol.281 (2), p.253-276

1996

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New synthetic heparin mimetics able to inhibit thrombin and factor Xa

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1155-1160

1999

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Synthetic oligosaccharides having various functional domains: Potent and potentially safe heparin mimetics

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1161-1166

1999

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Binding of heparan sulfate to fibroblast growth factor-2 total synthesis of a putative pentasaccharide binding site

Tetrahedron: asymmetry, 1996-11, Vol.7 (11), p.3119-3128

1996

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Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for ‘polymerisation’

Carbohydrate research, 1999-04, Vol.317 (1), p.63-84

1999

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Synthesis of a 3-deoxy- l-iduronic acid containing heparin pentasaccharide to probe the conformation of the antithrombin III binding sequence

Bioorganic & medicinal chemistry, 1998-08, Vol.6 (8), p.1337-1346

1998

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Synthesis of Conformationally Locked l-Iduronic Acid Derivatives: Direct Evidence for a Critical Role of the Skew-Boat 2S0 Conformer in the Activation of Antithrombin by Heparin

Chemistry : a European journal, 2001-11, Vol.7 (22), p.4821-4834

2001

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Assessment through chemical synthesis of the size of the heparin sequence involved in thrombin inhibition

Carbohydrate research, 1999-04, Vol.317 (1), p.85-99

1999

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Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III

Carbohydrate research, 1987-09, Vol.167, p.67-75

1987

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Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

Bioorganic & medicinal chemistry letters, 1997-11, Vol.7 (22), p.2843-2846

1997

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Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

Experimental Proof for the Structure of a Thrombin-Inhibiting Heparin Molecule

The structure of synthetic oligosaccharides in relation to factor IXa inhibition

Synthesis of thrombin-inhibiting heparin mimetics without side effects

Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

SR123781A, a synthetic heparin mimetic

The Synthetic Pentasaccharide Fondaparinux: First in the Class of Antithrombotic Agents that Selectively Inhibit Coagulation Factor Xa

A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity

A new, highly potent, heparin-like pentasaccharide fragment containing a glucose residue instead of a glucosamine

A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin

p-Anisyl ethers in carbohydrate chemistry: Selective protection of the primary alcohol function

The first total synthesis of the antithrombin III binding site of porcine mucosa heparin

Synthesis and Pharmacological Properties of a Close Analogue of an Antithrombotic Pentasaccharide (SR 90107A/ORG 31540)

l-Iduronic acid derivatives as glycosyl donors

New synthetic heparin mimetics able to inhibit thrombin and factor Xa

Synthetic oligosaccharides having various functional domains: Potent and potentially safe heparin mimetics

Binding of heparan sulfate to fibroblast growth factor-2 total synthesis of a putative pentasaccharide binding site

Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for ‘polymerisation’

Synthesis of a 3-deoxy- l-iduronic acid containing heparin pentasaccharide to probe the conformation of the antithrombin III binding sequence

Synthesis of Conformationally Locked l-Iduronic Acid Derivatives: Direct Evidence for a Critical Role of the Skew-Boat 2S0 Conformer in the Activation of Antithrombin by Heparin

Assessment through chemical synthesis of the size of the heparin sequence involved in thrombin inhibition

Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III

Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

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