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Peptidomimetic Inhibitors of the Human Cytomegalovirus Protease

Journal of medicinal chemistry, 1997-12, Vol.40 (25), p.4113-4135

1997

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Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S228-S229

2016

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PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S707-S707

2016

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P72 ORAL TREATMENT WITH PBI-4050, A NOVEL FIRST-IN-CLASS ANTI-FIBROTIC COMPOUND, REDUCES HEPATIC FIBROSIS AND HEPATOCELLULAR CARCINOMA

Journal of hepatology, 2014-04, Vol.60 (1), p.S90-S90

2014

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Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase with Improved in Vivo Antiviral Activity

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4173-4180

1996

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Inhibition of herpes simplex virus type 1 ribonucleotide reductase by substituted tetrapeptide derivatives

Journal of medicinal chemistry, 1993-10, Vol.36 (20), p.3005-3009

1993

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Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents

Journal of medicinal chemistry, 1995-09, Vol.38 (18), p.3617-3623

1995

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Ureido-Based Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase: An Investigation of Inhibitor Bioactive Conformation

Journal of medicinal chemistry, 1996-05, Vol.39 (11), p.2178-2187

1996

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FRI-104 - PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

Journal of hepatology, 2018-04, Vol.68, p.S408-S408

2018

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PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

Journal of hepatology, 2018-04, Vol.68, p.S408

2018

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Specific inhibition of ribonucleotide reductases by peptides corresponding to the C-terminal of their second subunit

Biochemistry and cell biology, 1991-01, Vol.69 (1), p.79-83

1991

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THU-281 - Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S228-S229

2016

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SAT-405 - PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S707-S707

2016

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B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Nintedanib

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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B110 NOVEL THERAPIES AND TARGETS IN FIBROSIS: Oral Treatment With Pbi-4050 Reduces Serum And Lung Anti-Inflammatory/fibrotic Biomarkers

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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C74 MODELS AND METHODS IN LUNG BIOLOGY: Oral Treatment With Pbi-4050 Reduces Plasminogen Activator Inhibitor-1 (pai-1), Alpha-Smooth Muscle Actin ([alpha]-Sma) and Collagen Expression In Human Fibroblasts And Mice Fibrotic Lungs

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A60 LUNG FIBROSIS: ANIMAL MODELS I: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Pirfenidone

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Oral Treatment With Pbi-4050 Reduces Lung Fibrosis

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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Synthesis of chiral vinylglycines

Journal of organic chemistry, 1991-06, Vol.56 (13), p.4196-4204

1991

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Renal fibrosis and progression

Nephrology, dialysis, transplantation, 2013-05, Vol.28 (suppl 1), p.i27-i27

2013

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Diabetes - basic research

Nephrology, dialysis, transplantation, 2013-05, Vol.28 (suppl 1), p.i50-i51

2013

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Potent Inhibitors of the Hepatitis C Virus NS3 Protease: Design and Synthesis of Macrocyclic Substrate-Based β-Strand Mimics

Journal of organic chemistry, 2004-09, Vol.69 (19), p.6185-6201

2004

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Synthesis of 5H-imidazo[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepine

Journal of heterocyclic chemistry, 1984-11, Vol.21 (6), p.1685-1687

1984

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ChemInform Abstract: Large Scale Preparation of (2S,3S)-N-Boc-3-Amino-1,2-epoxy-4- phenylbutane: A Key Building Block for HIV-Protease Inhibitors

ChemInform, 1995-08, Vol.26 (35), p.no-no

1995

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ChemInform Abstract: Preparation of Enantiopure 4-Oxygenated Pipecolic Acid Derivatives

ChemInform, 1998-03, Vol.29 (9), p.no-no

1998

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Peptidomimetic Inhibitors of the Human Cytomegalovirus Protease

Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

P72 ORAL TREATMENT WITH PBI-4050, A NOVEL FIRST-IN-CLASS ANTI-FIBROTIC COMPOUND, REDUCES HEPATIC FIBROSIS AND HEPATOCELLULAR CARCINOMA

Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase with Improved in Vivo Antiviral Activity

Inhibition of herpes simplex virus type 1 ribonucleotide reductase by substituted tetrapeptide derivatives

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents

Ureido-Based Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase: An Investigation of Inhibitor Bioactive Conformation

FRI-104 - PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

Specific inhibition of ribonucleotide reductases by peptides corresponding to the C-terminal of their second subunit

THU-281 - Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

SAT-405 - PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Nintedanib

B110 NOVEL THERAPIES AND TARGETS IN FIBROSIS: Oral Treatment With Pbi-4050 Reduces Serum And Lung Anti-Inflammatory/fibrotic Biomarkers

C74 MODELS AND METHODS IN LUNG BIOLOGY: Oral Treatment With Pbi-4050 Reduces Plasminogen Activator Inhibitor-1 (pai-1), Alpha-Smooth Muscle Actin ([alpha]-Sma) and Collagen Expression In Human Fibroblasts And Mice Fibrotic Lungs

A60 LUNG FIBROSIS: ANIMAL MODELS I: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Pirfenidone

B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Oral Treatment With Pbi-4050 Reduces Lung Fibrosis

Synthesis of chiral vinylglycines

Renal fibrosis and progression

Diabetes - basic research

Potent Inhibitors of the Hepatitis C Virus NS3 Protease: Design and Synthesis of Macrocyclic Substrate-Based β-Strand Mimics

Synthesis of 5H-imidazo[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepine

ChemInform Abstract: Large Scale Preparation of (2S,3S)-N-Boc-3-Amino-1,2-epoxy-4- phenylbutane: A Key Building Block for HIV-Protease Inhibitors

ChemInform Abstract: Preparation of Enantiopure 4-Oxygenated Pipecolic Acid Derivatives

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